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Breast cancer deaths decline in young women across all racial and subtype groups

From 2010 to 2020, breast cancer deaths among women ages 20-49 declined significantly across all breast cancer subtypes and racial/ethnic groups, with marked declines starting after 2016, according to an analysis of data from the Surveillance, Epidemiology, and End Results (SEER) registry presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Study links pregnancy specific genes to poorer lung cancer outcomes in women

Lung cancer can co-opt genes that normally help a fetus develop and evade the mother's immune system. And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men and women, female patients had poorer outcomes, a Memorial Sloan Kettering Cancer Center (MSK) research team has found.

29 Apr 2025

Financial Toxicity Tumor Board approach provides relief from cancer treatment costs

Financial toxicity, the financial distress linked to cancer treatment, significantly impacts patient outcomes. To combat this, the Atrium Health Levine Cancer Institute established a Financial Toxicity Tumor Board in 2019.

29 Apr 2025

HonorHealth unveils first study from new Phoenix lab targeting pancreatic cancer

HonorHealth Research Institute's new downtown Phoenix laboratory has produced its first study, centered on a promising new treatment for pancreatic cancer, one of the most aggressive and difficult to treat of all malignancies.

29 Apr 2025

HonorHealth Research Institute treats first patient in global trial targeting aggressive melanoma

HonorHealth Research Institute recently treated the first patient in a 50-site international clinical trial that will test a new type of therapy aimed at difficult-to-treat melanoma, an aggressive type of skin cancer.

29 Apr 2025

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Announcing a new article publication for BIO Integration journal. Bladder cancer (BLCA) is one of the most common malignancies and the second most frequent urogenital tract tumor.

29 Apr 2025

Tailored treatment guided by dual biopsy approach may improve outcomes for patients with advanced cancers

Patients with advanced solid tumors experienced significantly improved survival outcomes when receiving a tailored therapy based on the detection of the same genomic alteration in both tissue and liquid biopsies compared with both standard-of-care treatment and tailored therapy that was based on either biopsy on its own, according to results from the phase II, multicenter ROME trial presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Genetic variation found to influence tumor microbiota and colorectal cancer progression

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an important role in both the onset and progression of CRC, emerging evidence points to the significance of intratumoral microbiota-microbiota inside tumors-in CRC progression.

29 Apr 2025

New CAR T cell therapy shows promise for treating advanced thyroid cancer

A new chimeric antigen receptor (CAR) T cell therapy called AIC100, which targets the ICAM-1 protein, demonstrated encouraging responses and an acceptable safety profile in patients with two types of advanced thyroid cancer, according to researchers from The University of Texas MD Anderson Cancer Center.

29 Apr 2025

‘Game-changer’ clinical trial launches for Australia’s second-deadliest cancer

A world-first clinical trial launched in Melbourne is being hailed a ‘game-changer’ for its potential to revolutionize the way people with bowel cancer are treated.

29 Apr 2025

Predictive model could improve treatment decisions for advanced pancreatic cancer patients

Researchers in Japan have developed a predictive model that could improve treatment decisions for advanced pancreatic cancer patients.

28 Apr 2025

Simple urine sample could revolutionize early prostate cancer diagnosis

A newly published study involving researchers from Karolinska Institutet indicates that prostate cancer can be diagnosed at an early stage through a simple urine sample.

28 Apr 2025

Influenza virus hijacks human gene regulator to evade immune system

The influenza virus manipulates the body's gene regulation system to accelerate its own spread, according to researchers at the University of Gothenburg.

28 Apr 2025

Study evaluates long-term outcomes of gamma knife radiosurgery in patients with grade 2 meningiomas

The role of radiosurgery in the treatment of grade 2 meningioma remains unclear. This study aimed to evaluate the long-term outcomes of gamma knife radiosurgery (GKRS) in patients with grade 2 meningiomas and to identify factors influencing tumor control and survival.

28 Apr 2025

New $224 million proton therapy center coming to Penn Presbyterian

Today, Penn Medicine celebrated the groundbreaking of the Roberts Proton Therapy Center at Penn Presbyterian Medical Center in University City, which is expected to open for patient care in late 2027.

28 Apr 2025

Immunotherapy replaces surgery for early-stage dMMR cancers in landmark study

Neoadjuvant PD-1 blockade with dostarlimab achieved high rates of organ preservation in patients with early-stage mismatch repair-deficient (dMMR) solid tumors across multiple types. Most patients avoided surgery with durable disease control, reshaping potential cancer treatment pathways.

28 Apr 2025

Humanized antibody dismantles metabolic barrier as a potential cancer immunotherapy

A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses.

28 Apr 2025

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial

The HER2-targeted therapy zongertinib demonstrated clinical benefits for previously treated patients with advanced HER2-mutant non-small cell lung cancer – particularly those with specific HER2 mutations – with manageable side effects, according to results from the Phase Ia/Ib Beamion LUNG-1 trial led by researchers from The University of Texas MD Anderson Cancer Center.

28 Apr 2025

New topical gel reduces painful rash from colorectal cancer treatment

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center and The University of Texas MD Anderson Cancer Center have demonstrated that a novel topical BRAF inhibitor gel called LUT014 significantly reduces the severity of an acne-like rash, a common and painful side effect experienced by patients undergoing anti-EGFR therapies for colorectal cancer.

28 Apr 2025

High cannabis use associated with increased colon cancer mortality

Researchers at the University of California San Diego School of Medicine have found that individuals with colon cancer and a documented history of high cannabis use were more than 20 times more likely to die within five years of diagnosis compared to those without such a history.

28 Apr 2025

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Tumor News and Research

Breast cancer deaths decline in young women across all racial and subtype groups

Study links pregnancy specific genes to poorer lung cancer outcomes in women

Financial Toxicity Tumor Board approach provides relief from cancer treatment costs

HonorHealth unveils first study from new Phoenix lab targeting pancreatic cancer

HonorHealth Research Institute treats first patient in global trial targeting aggressive melanoma

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Tailored treatment guided by dual biopsy approach may improve outcomes for patients with advanced cancers

Genetic variation found to influence tumor microbiota and colorectal cancer progression

New CAR T cell therapy shows promise for treating advanced thyroid cancer

‘Game-changer’ clinical trial launches for Australia’s second-deadliest cancer

Predictive model could improve treatment decisions for advanced pancreatic cancer patients

Simple urine sample could revolutionize early prostate cancer diagnosis

Influenza virus hijacks human gene regulator to evade immune system

Study evaluates long-term outcomes of gamma knife radiosurgery in patients with grade 2 meningiomas

New $224 million proton therapy center coming to Penn Presbyterian

Immunotherapy replaces surgery for early-stage dMMR cancers in landmark study

Humanized antibody dismantles metabolic barrier as a potential cancer immunotherapy

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial

New topical gel reduces painful rash from colorectal cancer treatment

High cannabis use associated with increased colon cancer mortality

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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