Immune System News and Research

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Simple means of improving binding affinity of synbodies

Antibodies are watchdogs of human health, continuously prowling the body and registering minute changes associated with infection or disease with astonishing acuity. They also serve as biochemical memory banks, faithfully recording information about pathogens they encounter and efficiently storing this data for later use.

25 Jan 2011

Research finds faster developmental rate incurs lethal physiological costs for individuals

Fast development is often perceived as an advantage, as it enables better harmony with one's environment and readiness to cope with the challenges that it poses. However, research conducted at the University of Haifa, Israel, and University of California, Santa Cruz, and published in the scientific journal PLoS ONE, found that the acceleration of developmental rate incurs potentially lethal physiological costs for the developing individual.

25 Jan 2011

Also in Global Health News: Cholera death in DR; TB vaccine study; Rising food prices

"Dominican Republic on Sunday confirmed that a 53-year-old Haitian man has become the country's first death from cholera and announced the immediate start of a broad disease control and monitoring operation" around the eastern town of Higuey where he was being treated and later died, Latin American Herald Tribune reports (1/24).

24 Jan 2011

Agenus enters research agreement with Memorial Sloan-Kettering Cancer Center

Agenus Inc. today announced it has entered into a research agreement with Memorial Sloan-Kettering Cancer Center (MSKCC) using Agenus' proprietary cancer vaccine technology.

24 Jan 2011

Northwest Biotherapeutics resumes enrollment in DCVax Phase II clinical trial for GBM brain cancer

Northwest Biotherapeutics announced today that the Company is resuming enrollment of additional new patients into its ongoing 240-patient, double blind, randomized, placebo controlled Phase II clinical trial of DCVax for Glioblastoma multiforme brain cancer.

24 Jan 2011

Positive interim data from ongoing V5 Phase IIb imm01 trial against tuberculosis

Immune Network, a company in the business of development and commercialization of immune therapies, announced today that its newly acquired business, Immunitor, has published interim data from the ongoing Phase IIb imm01 clinical trial of V5 in tuberculosis conducted at its second site in Ukraine.

24 Jan 2011

Research findings reveal HIV's hiding spot, new way to stop the virus

HIV adapts in a surprising way to survive and thrive in its hiding spot within the human immune system, scientists have learned. While the finding helps explain why HIV remains such a formidable foe after three decades of research - more than 30 million people worldwide are infected with HIV - it also offers scientists a new, unexpected way to try to stop the virus.

24 Jan 2011

SuppreMol completes successful pre-IND meeting with U.S. FDA

SuppreMol GmbH, a privately held biopharmaceutical company developing innovative therapeutics for the treatment of autoimmune diseases, today announced that it has successfully completed a pre-Investigational New Drug Application (pre-IND) meeting with the U.S. Food and Drug Administration (FDA) for its lead compound SM101, which is being developed for the treatment of Primary Immune Thrombocytopenia (ITP) and Systemic Lupus Erythematosus (SLE).

24 Jan 2011

CRI, Oncovir sign new investment agreement to produce immunological stimulant

Cancer Research Institute, a U.S. nonprofit organization founded in 1953 to advance the science of tumor immunology and foster the discovery and development of new cancer immunotherapies, announced today that its Cancer Vaccine Acceleration Fund, a joint initiative with the Ludwig Institute for Cancer Research, has completed a new investment agreement with Oncovir, a biotechnology company based in Washington, D.C., to enable the production of the immunological stimulant Hiltonol- (Poly-ICLC).

24 Jan 2011

Odontoblast cells are part of immune system, protect teeth from decay: New research

It is known that teeth can protect themselves, to some extent, from attack by bacteria but that inflammation within a tooth can be damaging and, in extreme cases, lead to abscess or death of the tooth. New research published in BioMed Central's open access journal BMC Immunology shows that odontoblast cells are part of the immune system and fight to protect teeth from decay.

23 Jan 2011

CVAF completes new investment agreement with Oncovir for production of Hiltonol

Cancer Research Institute, Inc. (CRI), a U.S. nonprofit organization founded in 1953 to advance the science of tumor immunology and foster the discovery and development of new cancer immunotherapies, announced today that its Cancer Vaccine Acceleration Fund (CVAF), a joint initiative with the Ludwig Institute for Cancer Research (LICR), has completed a new investment agreement with Oncovir, Inc., a biotechnology company based in Washington, D.C., to enable the production of the immunological stimulant Hiltonol® (Poly-ICLC).

21 Jan 2011

AHF proposes funding solutions to current ADAP crisis

In anticipation of an additional round of cuts to the AIDS Drug Assistance Program (ADAP) to be implemented in the next few months, AIDS Healthcare Foundation (AHF) today proposed three possible funding solutions to the current ADAP crisis—which has left more than 5,000 people on waiting lists to receive lifesaving medications and thousands more scheduled to be disenrolled from the program altogether. Currently,

21 Jan 2011

Researchers map complex choreography used by immune system's T cells to recognize pathogens

Researchers have for the first time mapped the complex choreography used by the immune system's T cells to recognize pathogens while avoiding attacks on the body's own cells.

21 Jan 2011

Vibrio cholerae kills E. coli bacteria

Just over a year after the earthquake in Haiti killed 222,000 people there's a new problem that is killing Haitians. A cholera outbreak has doctors in the area scrambling and the water-borne illness has already claimed 3600 lives according to officials with M-dicin Sans Fronti-res (Doctors without Borders).

21 Jan 2011

Fat linked with DNA chemical changes may help identify risk of cardiovascular disease, diabetes

Fat appears to associate with some distinctive chemical changes in the DNA - a finding that may help explain why obesity can increase the risk for chronic problems such as cardiovascular disease and diabetes, researchers report.

21 Jan 2011

New research says EPO hormone can modulate immune response

New research reveals that a hormone best known for stimulating the production of red blood cells can modulate the immune response. The study, published by Cell Press in the January 27th issue of the journal Immunity, finds that erythropoietin has contrasting influences on infectious and inflammatory diseases and may be useful in the design of new therapeutic strategies.

21 Jan 2011

Scientists find ADAR1 enzyme protect against measles virus

Scientists at The Scripps Research Institute have found that a known enzyme in cells protects against measles virus, likely by altering the virus's genetic material, RNA. Cells lacking the enzyme become highly vulnerable to the virus's destructive effects. The enzyme also protects against several other respiratory viruses, including influenza A.

21 Jan 2011

BUSM receives NIH grant to explore how chronic inflammation can lead to systemic diseases

A team of researchers at Boston University School of Medicine have been awarded a five-year, $7.7 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Diseases to explore how chronic inflammation can lead to systemic diseases.

20 Jan 2011

FDA grants Soligenix Orphan Drug Designation to RiVax for prevention of ricin intoxication

Soligenix, Inc., a late-stage biopharmaceutical company, announced today that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation to RiVax™ for the prevention of ricin intoxication. RiVax™ is a proprietary vaccine that contains a recombinant subunit of the A chain of ricin toxin which induces ricin neutralizing antibodies in humans and animals.

20 Jan 2011

Clinical Immunology Research Laboratory at The Mount Sinai Medical Center receives Octapharma grant

Octapharma USA today announced the second grant recipient of the Octapharma 25th Anniversary Grants Program is the Clinical Immunology Research Laboratory at The Mount Sinai Medical Center. The Octapharma Grants program supports clinical or pre-clinical research focused on human protein therapies in hematology, immune therapy, intensive care and emergency medicine.

20 Jan 2011

Immune System News and Research

Simple means of improving binding affinity of synbodies

Research finds faster developmental rate incurs lethal physiological costs for individuals

Also in Global Health News: Cholera death in DR; TB vaccine study; Rising food prices

Agenus enters research agreement with Memorial Sloan-Kettering Cancer Center

Northwest Biotherapeutics resumes enrollment in DCVax Phase II clinical trial for GBM brain cancer

Positive interim data from ongoing V5 Phase IIb imm01 trial against tuberculosis

Research findings reveal HIV's hiding spot, new way to stop the virus

SuppreMol completes successful pre-IND meeting with U.S. FDA

CRI, Oncovir sign new investment agreement to produce immunological stimulant

Odontoblast cells are part of immune system, protect teeth from decay: New research

CVAF completes new investment agreement with Oncovir for production of Hiltonol

AHF proposes funding solutions to current ADAP crisis

Researchers map complex choreography used by immune system's T cells to recognize pathogens

Vibrio cholerae kills E. coli bacteria

Fat linked with DNA chemical changes may help identify risk of cardiovascular disease, diabetes

New research says EPO hormone can modulate immune response

Scientists find ADAR1 enzyme protect against measles virus

BUSM receives NIH grant to explore how chronic inflammation can lead to systemic diseases

FDA grants Soligenix Orphan Drug Designation to RiVax for prevention of ricin intoxication

Clinical Immunology Research Laboratory at The Mount Sinai Medical Center receives Octapharma grant

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