Respiratory News and Research

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Amyotrophic lateral sclerosis in veterans: an interview with Milan Michael Karol, The Robert Packard Center for ALS Research at Johns Hopkins

ALS stands for Amyotrophic Lateral Sclerosis, better known as “Lou Gehrig’s Disease”. It is a progressive neurodegenerative disease characterized by the death of motor neurons in the brain and spinal cord.

30 Jun 2014

New research project aims to tackle antibiotic resistance with inhalable nanotherapeutics

A new research project (PneumoNP) is aimed at tackling antibiotic resistance in respiratory tract infections via the use of inhalable nanotherapeutic compounds. Funded under the FP7 programme by the European Commission, the 4-year long PneumoNP project brings together top research institutes, universities, clinicians and enterprises from 6 EU member states.

28 Jun 2014

Study explores metabolic activities of unique microbes for cleaning environmental contaminants

Chlorinated chemicals perform a host of societally useful functions, but they also have a dark side. Once their use life has ended, such agents often become environmental contaminants, sometimes resistant to bioremediation.

28 Jun 2014

Vertex receives positive opinion from European CHMP for approval of KALYDECO for cystic fibrosis

Vertex Pharmaceuticals Incorporated today announced that the European Committee for Medicinal Products for Human Use has issued a positive opinion recommending the approval of KALYDECO (ivacaftor) for people with cystic fibrosis (CF) ages 6 and older who have one of eight non-G551D gating mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

28 Jun 2014

ALS is aggravated by over-activity of HDAC6 enzyme, shows study

Scientists at VIB and KU Leuven have demonstrated in fruit-flies that over-activity of the enzyme HDAC6 in the nerve ends exacerbates the symptoms of the neurodegenerative condition Amyotrophic Lateral Sclerosis (ALS / Lou Gehrig's Disease). Inhibition of this enzyme could offer a protective effect against ALS.

27 Jun 2014

New article explores how specific types of interferons control RNA virus infection

Respiratory and intestinal infections caused by RNA viruses stimulate infected cells to produce interferons, which can act alone or in combination to block virus replication.

27 Jun 2014

Motivational interviewing reduces secondhand smoke exposure among children living in households

A Johns Hopkins-led research team has found that motivational interviewing, along with standard education and awareness programs, significantly reduced secondhand smoke exposure among children living in those households.

26 Jun 2014

Research: TB infection among people taking corticosteroid pills may be underestimated

Tuberculosis infection among people taking corticosteroid pills may be underestimated, new research suggests.

26 Jun 2014

Queen's doctor plays key role in major breakthrough to change lives of cystic fibrosis sufferers

A Queen's University doctor has played a key role in a major breakthrough to change the lives of cystic fibrosis sufferers.

26 Jun 2014

Henry Ford launches clinical trial for treatment of tinnitus caused by noise trauma

Henry Ford Health System has launched a clinical trial to investigate a new drug for the treatment of tinnitus, a chronic ringing of the head or ears that affects more than 600 million people worldwide.

25 Jun 2014

St. Mary's Medical Center honored with Healthgrades 2014 Women's Health Excellence Award

Dignity Health St. Mary's Medical Center has received the 2014 Women's Health Excellence Award from Healthgrades, the leading online resource for comprehensive information about physicians and hospitals.

25 Jun 2014

Trevena's Phase 1b data for TRV130 published in the journal Pain

Trevena, Inc., a clinical stage biopharmaceutical company and the leader in the discovery of G protein coupled receptor (GPCR) biased ligands, today announced the publication of its Phase 1b data for TRV130 in the journal Pain.

24 Jun 2014

Nearly 4% of U.S. babies are born before full-term without medical indication, study finds

A large new study, covering millions of U.S. births over 15 years, finds that substantial numbers of babies, nearly one in 25, are born earlier than medically justified, through elective cesarean sections and elective induced labor. The study reinforces long-standing recommendations by professional medical and public health organizations against early-term deliveries without appropriate medical reasons.

24 Jun 2014

Forest Laboratories reports positive results from three Phase III trials of vilazodone for GAD treatment

Forest Laboratories, Inc. today announced positive topline results from three Phase III trials evaluating the efficacy, safety and tolerability of vilazodone in adult patients with generalized anxiety disorder (GAD).

24 Jun 2014

Scientists turn to old class of antibiotics to fight superbugs resistant to modern medicine

Scientists at the University at Buffalo are turning to an old class of antibiotics to fight new superbugs resistant to modern medicine.

24 Jun 2014

Private insurers clamp down on drug prices

More health plans are refusing to cover certain brand-name drugs unless drugmakers offer discounts for them, reports The New York Times.

23 Jun 2014

Aradigm begins Pulmaquin Phase III study for treatment of non-CF BE

Aradigm Corporation ("Aradigm" or the "Company") today announced the dosing of the first patient in the ORBIT-4 (Once-daily Respiratory Bronchiectasis Inhalation Treatment) Phase III pivotal clinical trial of Aradigm's proprietary formulation of inhaled ciprofloxacin (Pulmaquin®) for the treatment of non-cystic fibrosis bronchiectasis (non-CF BE).

23 Jun 2014

Trevena reports positive results from TRV734 Phase 1 trial for treating acute/chronic pain

Trevena, Inc. (NASDAQ:TRVN) today announced positive results from its Phase 1 trial of TRV734, which Trevena is developing with the goal of providing improved analgesia while avoiding gastrointestinal and respiratory side effects typically associated with opioids.

23 Jun 2014

First Edition: June 23, 2014

Today's early morning highlights from the major news organizations, including news stories about healthcare.gov management changes.

23 Jun 2014

National, state air pollution controls decrease death rates in North Carolina

National and state air pollution controls that went into effect in the early 1990s coincide with decreasing death rates from emphysema, asthma and pneumonia among people in North Carolina, according to a study led by Duke University researchers.

23 Jun 2014

Respiratory News and Research

Amyotrophic lateral sclerosis in veterans: an interview with Milan Michael Karol, The Robert Packard Center for ALS Research at Johns Hopkins

New research project aims to tackle antibiotic resistance with inhalable nanotherapeutics

Study explores metabolic activities of unique microbes for cleaning environmental contaminants

Vertex receives positive opinion from European CHMP for approval of KALYDECO for cystic fibrosis

ALS is aggravated by over-activity of HDAC6 enzyme, shows study

New article explores how specific types of interferons control RNA virus infection

Motivational interviewing reduces secondhand smoke exposure among children living in households

Research: TB infection among people taking corticosteroid pills may be underestimated

Queen's doctor plays key role in major breakthrough to change lives of cystic fibrosis sufferers

Henry Ford launches clinical trial for treatment of tinnitus caused by noise trauma

St. Mary's Medical Center honored with Healthgrades 2014 Women's Health Excellence Award

Trevena's Phase 1b data for TRV130 published in the journal Pain

Nearly 4% of U.S. babies are born before full-term without medical indication, study finds

Forest Laboratories reports positive results from three Phase III trials of vilazodone for GAD treatment

Scientists turn to old class of antibiotics to fight superbugs resistant to modern medicine

Private insurers clamp down on drug prices

Aradigm begins Pulmaquin Phase III study for treatment of non-CF BE

Trevena reports positive results from TRV734 Phase 1 trial for treating acute/chronic pain

First Edition: June 23, 2014

National, state air pollution controls decrease death rates in North Carolina

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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