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New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

A new class of glioma drugs exploits tumors that lack the DNA repair enzyme MGMT; the drugs lead to the generation of cytotoxic DNA and selectively kill tumor cells without the risk of resistance, researchers report.

29 Jul 2022

Newly developed bioadhesive ultrasound helps in long-term continuous imaging of diverse organs

A wearable ultrasound device attached using a durable, adhesive, stretchy material enables continuous medical imaging of internal organs and tissues for patients on the go, researchers report. They tested their patch in real people doing activities like jogging and drinking fluids.

29 Jul 2022

The bat-virus relationship examined

A new study examines the role of bats as reservoirs of several viruses and the factors that contribute to the emergence of these viruses.

28 Jul 2022

TMPRSS2 protein, a novel target for SARS-CoV-2 drugs

A new study reports the activity of a compound which inhibited TMPRSS2, ultimately preventing severe COVID-19.

28 Jul 2022

The identification and characterization of an anti-SARS-CoV-2 monoclonal antibody with superior breadth and potency

A recent study published in Nature Microbiology identified a monoclonal antibody neutralizing SARS-CoV-2 Omicron variants.

28 Jul 2022

The effects of CBD in the treatment of COVID-19–related inflammatory symptoms

Researchers reviewed the effectiveness of cannabidiol in treating COVID-19 inflammatory-related symptoms.

28 Jul 2022

Mesoporous silica nanoparticles: Possibilities in therapeutic development

In this interview, News-Medical talks to Philippe Riviere, Senior Scientist at NanoComposix (now a Fortis Life Sciences company) about mesoporous silica nanoparticles and the possibilities and opportunities they provide to drug delivery, vaccine development and more.

From nanoComposix 28 Jul 2022

Study finds molnupiravir well-tolerated, and effective in vaccinated and unvaccinated

Researchers report the phase II efficacy and safety of molnupiravir in both unvaccinated and vaccinated individuals.

27 Jul 2022

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

In a new study, investigators studied a linear deoxyribonucleic acid (linDNA) SARS-CoV-2 vaccine option in felines.

27 Jul 2022

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Researchers compared the potency of 17 human interferons (IFNs) against multiple SARS-CoV-2 variants.

27 Jul 2022

Temporal changes in CD4 T-lymphocyte dynamics upon immunization against SARS-CoV-2 spike protein

Researchers assessed changes in CD4 T-lymphocyte temporal dynamics by evaluating T-lymphocyte responses to SARS-CoV-2 S using Foxp3-Tocky mice and Nr4a3-Tocky mice.

27 Jul 2022

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

Researchers report the efficacy and safety of molnupiravir in treating COVID-19.

26 Jul 2022

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

A new study discusses the development of recombinant vesicular stomatitis virus COVID-19 vaccines.

25 Jul 2022

IU researchers evaluate the efficacy of a failed clinical trial drug for Alzheimer's using rigorous pipeline

Most drugs developed to treat Alzheimer's disease have for years been ineffective in clinical trials. Researchers from Indiana University School of Medicine recently evaluated the efficacy of a failed clinical trial drug using their rigorous pipeline.

25 Jul 2022

Study suggests a possible treatment approach for cancer and cardiovascular disease

A key molecule for cancer metastasis has been identified as a molecule already known for its involvement in cardiovascular disease, suggesting a possible treatment approach for both diseases simultaneously.

25 Jul 2022

Research reveals molecular clues associated with traumatic brain injury

New research led by scientists at Arizona State University has revealed some of the first detailed molecular clues associated with one of the leading causes of death and disability, a condition known as traumatic brain injury (TBI).

23 Jul 2022

Cancer cells produce small amount of collagen that impacts tumor microbiome and immunity

Cancer cells produce small amounts of their own form of collagen, creating a unique extracellular matrix that affects the tumor microbiome and protects against immune responses, according to a new study by researchers at The University of Texas MD Anderson Cancer Center.

21 Jul 2022

in vivo News and Research

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

Newly developed bioadhesive ultrasound helps in long-term continuous imaging of diverse organs

The bat-virus relationship examined

TMPRSS2 protein, a novel target for SARS-CoV-2 drugs

The identification and characterization of an anti-SARS-CoV-2 monoclonal antibody with superior breadth and potency

The effects of CBD in the treatment of COVID-19–related inflammatory symptoms

Mesoporous silica nanoparticles: Possibilities in therapeutic development

Study finds molnupiravir well-tolerated, and effective in vaccinated and unvaccinated

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Temporal changes in CD4 T-lymphocyte dynamics upon immunization against SARS-CoV-2 spike protein

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

IU researchers evaluate the efficacy of a failed clinical trial drug for Alzheimer's using rigorous pipeline

Study suggests a possible treatment approach for cancer and cardiovascular disease

Research reveals molecular clues associated with traumatic brain injury

Cancer cells produce small amount of collagen that impacts tumor microbiome and immunity

Unlocking the power of proteins to better understand human health

Should siRNA-based antivirals be added to the COVID toolbox?

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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