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Five recent Science and Nature papers shed light on elusive 'GPCRs'

Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with deep importance for biology and medicine.

14 Jul 2012

Sandia researchers develop SpinDx medical diagnostic tool

Researchers at Sandia National Laboratories have developed a lab-on-a-disk platform that they believe will be faster, less expensive and more versatile than similar medical diagnostic tools.

14 Jul 2012

Researchers define interaction between two essential proteins that control inflammation

Researchers at the IRCM, led by geneticist Dr. Jacques Drouin, recently defined the interaction between two essential proteins that control inflammation.

14 Jul 2012

Identification of IL-9 antitumor activity in melanoma

High expression of interleukin -9 in immune cells inhibits growth of melanoma, show study findings suggesting a role for this T-cell cytokine in tumor suppression.

13 Jul 2012

PEPFAR strengthens AIDS programs, broader health care systems, Goosby says

Describing PEPFAR as "a targeted approach on a large-scale and with accountability for results," U.S. Global AIDS Coordinator Ambassador Eric Goosby on Tuesday said the program has done more than fight HIV/AIDS, having had a "broader transformational impact ... on the health sector" in many countries, VOA News reports.

13 Jul 2012

Officials identify causes of 'mystery illness' responsible for more than 60 child deaths in Cambodia, CNN reports

According to physicians familiar with the investigation, the causes of the "mystery illness" that has killed more than 60 children in Cambodia have been identified, CNN reports. "A combination of pathogens ... is to blame for the illness, the World Health Organization, in conjunction with the Cambodian Ministry of Health, has concluded, the doctors said," according to the news service.

13 Jul 2012

Discovery sheds light on why human body is unable to fight off HIV infection

University of Washington researchers have made a discovery that sheds light on why the human body is unable to adequately fight off HIV infection.

13 Jul 2012

Altered immune function in relatives of schizophrenia patients

Schizophrenia patients and their unaffected first-degree relatives exhibit immune system alterations compared with mentally healthy individuals, researchers report.

12 Jul 2012

Potassium channel KIR4.1 clue to multiple sclerosis

The potassium channel KIR4.1 is a potential immune target in certain patients with multiple sclerosis, report researchers in TheNew England Journal of Medicine.

12 Jul 2012

Smokers at risk for recurrent hepatitis post-liver transplantation

Transplant recipients who smoke or have smoked increase their risk of viral hepatitis reinfection following liver transplantation according to new research available in the July issue of Liver Transplantation, a journal published by Wiley on behalf of American Association for the Study of Liver Diseases.

12 Jul 2012

Superorganism view of the human body

Amid the growing recognition that only a small fraction of the cells and genes in a typical human being are human, scientists are suggesting a revolutionary approach to developing new medicines and treatments to target both the human and non-human components of people. That's the topic of an article, which reviews work relating to this topic from almost 100 studies, in ACS' Journal of Proteome Research.

12 Jul 2012

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman School of Medicine at the University of Pennsylvania that will be published today in the New England Journal of Medicine.

12 Jul 2012

Scientists capture high-quality images of immune cell trafficking in a beating heart

Blood flow to the heart often is interrupted during a heart attack or cardiac surgery. But when blood flow resumes, the heart may still falter. That's because collateral damage can occur as blood re-enters the heart, potentially slowing recovery and causing future cardiac troubles.

12 Jul 2012

Physiologists, neuropathologists identify origin of cancer metastasis formation

It is not primary tumors that are responsible for the majority of cancer deaths, but rather their metastases. Physiologists and neuropathologists from the University of Zurich have now identified the origin of metastasis formation, thereby becoming the first to reveal the pathway of metastasizing intestinal cancer cells out of the blood stream. The results allow new approaches in the development of cancer therapies.

12 Jul 2012

SRI receives NIAID grant to develop HIV vaccine

The Scripps Research Institute has been awarded a grant expected to total more than $77 million from the National Institutes of Health's (NIH) National Institute of Allergy and Infectious Diseases (NIAID).

12 Jul 2012

Genes responsible for immune function are almost different in middle age than in early adulthood

Important insights that explain why our ability to ward off infection declines with age are published in a new research report in the July 2012 issue of the Genetics Society of America's journal, GENETICS.

12 Jul 2012

OncoSec establishes UCSF as second enrolling site for OMS-I110 Phase II Merkel cell carcinoma trial

OncoSec Medical Inc., a company developing the advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumors, announces it has established the University of California San Francisco (UCSF) as the second enrolling site for its Phase II Merkel cell carcinoma clinical trial (OMS-I110).

11 Jul 2012

Rheumatoid arthritis risk reduced by moderate alcohol consumption

Moderate consumption of alcohol is associated with a reduced risk of developing rheumatoid arthritis, suggests a study published on bmj.com today.

11 Jul 2012

Fatal outcome from HFMD is rare, says LUHS pediatric infectious disease specialist

A mysterious disease that has killed nearly 60 children in Cambodia has been identified by the World Health Organization as enterovirus 71. This virus is one among a family of viruses that cause a variety of illnesses, including a common childhood illness called hand, foot and mouth disease, but Andrew Bonwit, MD, pediatric infectious disease specialist at Loyola University Health System, says a fatal outcome from such illness is rare.

11 Jul 2012

TLR1 plays a critical role in protecting the body from food-borne illnesses

A naturally occurring protein called TLR1 plays a critical role in protecting the body from illnesses caused by eating undercooked pork or drinking contaminated water, according to new research from the University of Southern California (USC).

11 Jul 2012

Immune System News and Research

Five recent Science and Nature papers shed light on elusive 'GPCRs'

Sandia researchers develop SpinDx medical diagnostic tool

Researchers define interaction between two essential proteins that control inflammation

Identification of IL-9 antitumor activity in melanoma

PEPFAR strengthens AIDS programs, broader health care systems, Goosby says

Officials identify causes of 'mystery illness' responsible for more than 60 child deaths in Cambodia, CNN reports

Discovery sheds light on why human body is unable to fight off HIV infection

Altered immune function in relatives of schizophrenia patients

Potassium channel KIR4.1 clue to multiple sclerosis

Smokers at risk for recurrent hepatitis post-liver transplantation

Superorganism view of the human body

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

Scientists capture high-quality images of immune cell trafficking in a beating heart

Physiologists, neuropathologists identify origin of cancer metastasis formation

SRI receives NIAID grant to develop HIV vaccine

Genes responsible for immune function are almost different in middle age than in early adulthood

OncoSec establishes UCSF as second enrolling site for OMS-I110 Phase II Merkel cell carcinoma trial

Rheumatoid arthritis risk reduced by moderate alcohol consumption

Fatal outcome from HFMD is rare, says LUHS pediatric infectious disease specialist

TLR1 plays a critical role in protecting the body from food-borne illnesses

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