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New computer software capable of sifting through hundreds of cancer causing genetic mutations

Johns Hopkins engineers have devised innovative computer software that can sift through hundreds of genetic mutations and highlight the DNA changes that are most likely to promote cancer.

1 Sep 2009

Altered gene network interaction plays an important role in brain tumors

The interaction between a network of altered genes appears to play an important role in the development and progression of brain tumors, according to a study in the July 15 issue of JAMA.

1 Sep 2009

GS-101 effective in inhibiting and regressing corneal neovascularisation

Gene Signal, a company focused on developing innovative drugs to manage angiogenesis based conditions, today announced the publication of interim results from a phase II study suggesting that the antisense oligonucleotide GS-101 (eye drops) is safe and effective at inhibiting and regressing corneal neovascularisation (abnormal new blood vessel growth).

1 Sep 2009

Intrexon purchases assets and operations of Avalon Pharmaceutical

Intrexon Corporation, a privately held life sciences company focused on modular DNA control systems for biotherapeutics and other industry sectors, today announced the purchase of assets and operations of Avalon Pharmaceutical, Inc., a wholly-owned subsidiary of Clinical Data, Inc.

1 Sep 2009

Phase II result reveals effectiveness of GS-101 eye drops at inhibiting corneal neovascularisation

1 Sep 2009

Traditional lipid risk factors to be strong predictors of cardiovascular events according to a study

For patients with established heart disease who were treated with a statin, 18 novel biomarkers including C-reactive protein (CRP) did not predict future cardiovascular events such as heart attack and stroke, according to results of an analysis presented today at the 2009 European Society of Cardiology Congress in Barcelona, Spain.

1 Sep 2009

Research reveals that large non-coding RNA in mammals play an important role in telomere maintenance

A team of researchers from The Wistar Institute have shown that a large non-coding RNA in mammals and yeast plays a central role in helping maintain telomeres, the tips of chromosomes that contain important genetic information and help regulate cell division. Since this RNA also facilitates the formation of DNA at telomeres-a process that can protect aging cells and destabilize tumor cells-manipulating its expression may be useful in treating cancer and other diseases.

1 Sep 2009

New gene therapy vector developed for transferring therapeutic DNA to a cell's nucleus

A research report featured on the cover of the September 2009 print issue of The FASEB Journal describes how Australian scientists developed a new gene therapy vector that uses the same machinery that viruses use to transport their cargo into our cells. As a result of this achievement, therapeutic DNA can be transferred to a cell's nucleus far more efficiently than in the past, raising hopes for more effective treatment of genetic disorders and some types of cancers.

1 Sep 2009

High-fiber cereals make progress in taste

Consumer Reports evaluated 18 high-fiber cereals and found seven especially flavorful choices. The report notes that most Americans can stand to double their intake of fiber which can help control appetite and weight, and might help lower the risk of heart disease and type 2 diabetes.

1 Sep 2009

Study provides insights into genes that help maintain youthfulness of the skin

In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome."

1 Sep 2009

Elsevier publishes second edition of Signal Transduction

Elsevier, the world-leading publisher of scientific, technical and medical information products and services, announces the publication of the new second edition of Signal Transduction edited by Bastien D. Gomperts, Ijsbrand M. Kramer and Peter E.R. Tatham.

1 Sep 2009

Chlorella green food sourced from algae contains a wide range of essential nutrients

"While we can still take advantage of summer's fresh produce, ensuring a consistent supply of whole foods throughout the year can reap benefits for those focused on aging as healthfully as possible," says Michael E. Rosenbaum, M.D. "Chlorella, a super green food sourced from a fresh water algae, contains the widest range of essential nutrients available in any single food source, including potassium, all B vitamins, magnesium, zinc, iron and 18 vital amino acids." Though beneficial for all life stages, Sun Chlorella can especially help aging adults thanks to these health rewards.

1 Sep 2009

Mitoxantrone is highly efficient in suppressing multiple sclerosis

According to data supplied by the German Multiple Sclerosis Society's national MS register (DMSG - Deutsche Multiple Sklerose Gesellschaft), up to 10% of German MS patients have been treated with mitoxantrone in the past few years.

1 Sep 2009

New Vice President for Bioanalytical Development lab appointed by Cytovance Biologics

Cytovance Biologics LLC, a biopharmaceutical contract manufacturing company specializing in the production of therapeutic proteins and antibodies from mammalian cell culture, today announced the addition of Dr. Jeffrey Su as Vice President of Bioanalytical Development to its diverse and growing scientific staff. Dr. Su will head up the state of the art Bioanalytical Development laboratory supporting existing and new client needs.

1 Sep 2009

Celladon announces completion of patient enrollment for Phase 2 CUPID clinical trial

Celladon Corporation and Momentum Research, Inc. today announced completion of enrollment of the phase 2 double-blind portion of the Calcium Up-regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) trial. Momentum Research is Celladon’s consulting and management organization with clinical expertise in the development of cardiovascular products and trials.

31 Aug 2009

BrainStorm Cell Therapeutics partners with Protein Production to start production of clinical-grade stem cell therapeutic product

BrainStorm Cell Therapeutics Inc. (OTCBB:BCLI), a leading developer of adult stem cell technologies and therapeutics, announced today that it has entered into an agreement with Protein Production Services Ltd. (PPS), a leading manufacturing contractor, in order to start Good Manufacturing Practice (cGMP) production of its stem cell therapeutic product.

31 Aug 2009

Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing's sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. The research is published online today in the journal Oncogene.

31 Aug 2009

Spinal implant developed by Sanfor Clinic neurosurgeon receives FDA market clearance

Sanford Health, a comprehensive health care provider in the Upper Midwest, announced today a spinal implant developed by Sanford Clinic Neurosurgeon, Wilson Asfora, MD, Sanford Clinic Neurosurgery & Spine, has received United States Food and Drug Administration (FDA) 510(k) market clearance as a lumbar intervertebral body fusion device.

31 Aug 2009

Study reveals that downregulation of IRF-8 gene causes gum diseases, arthritis and osteoporosis

Investigators at Hospital for Special Surgery, collaborating with researchers from other institutions, have contributed to the discovery that a gene called interferon regulator factor-8 (IRF-8) is involved in the development of diseases such as periodontitis (gum disease), rheumatoid arthritis and osteoporosis. The study, which will be published online August 30, ahead of print, in the journal Nature Medicine, could lead to new treatments in the future.

31 Aug 2009

New molecular sensor could identify zinc-related diseases

Scientists have developed a new molecular sensor that can reveal the amount of zinc in cells, which could tell us more about a number of diseases, including type 2 diabetes. The research, published today in Nature Methods, opens the door to the hidden world of zinc biology by giving scientists an accurate way of measuring the concentration of zinc and its location in cells for the first time.

30 Aug 2009

G Protein News and Research

New computer software capable of sifting through hundreds of cancer causing genetic mutations

Altered gene network interaction plays an important role in brain tumors

GS-101 effective in inhibiting and regressing corneal neovascularisation

Intrexon purchases assets and operations of Avalon Pharmaceutical

Phase II result reveals effectiveness of GS-101 eye drops at inhibiting corneal neovascularisation

Traditional lipid risk factors to be strong predictors of cardiovascular events according to a study

Research reveals that large non-coding RNA in mammals play an important role in telomere maintenance

New gene therapy vector developed for transferring therapeutic DNA to a cell's nucleus

High-fiber cereals make progress in taste

Study provides insights into genes that help maintain youthfulness of the skin

Elsevier publishes second edition of Signal Transduction

Chlorella green food sourced from algae contains a wide range of essential nutrients

Mitoxantrone is highly efficient in suppressing multiple sclerosis

New Vice President for Bioanalytical Development lab appointed by Cytovance Biologics

Celladon announces completion of patient enrollment for Phase 2 CUPID clinical trial

BrainStorm Cell Therapeutics partners with Protein Production to start production of clinical-grade stem cell therapeutic product

Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Spinal implant developed by Sanfor Clinic neurosurgeon receives FDA market clearance

Study reveals that downregulation of IRF-8 gene causes gum diseases, arthritis and osteoporosis

New molecular sensor could identify zinc-related diseases

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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