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New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects.

31 Jan 2020

Multimodal analysis of tumors could give new insights into treating cancer patients

Melding the genetic and cellular analysis of tumors with how they appear in medical images could give physicians and other cancer therapy specialists new insights into how to best treat patients, especially those with brain cancer, according to a new study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

31 Jan 2020

MSU researcher makes strides in discovering new cellular mechanism

A Montana State University biotechnology researcher was part of an international team that recently discovered an internal mechanism which may protect human cells from oxidative damage.

30 Jan 2020

UW creates new integrated center to accelerate development of biomedical discoveries

With $4 million in matching funds from the National Institutes of Health, the University of Washington has created a new integrated center to match biomedical discoveries with the resources needed to bring innovative products to the public and improve health.

30 Jan 2020

Potential new biomarker for vascular dementia identified

Vascular dementia is caused by a defect on blood flow arrival to the brain, which consequently generates neuronal damage.

30 Jan 2020

Turning stink into therapy for atherosclerosis

In an amusing but amazing turnaround, it seems the most foul-smelling compound on earth, called putrescine, could help relieve chronic inflammation, most importantly in the arterial thickening called atherosclerosis. This discovery is reported in the journal Cell Metabolism in January 2020.

30 Jan 2020

Gene-editing taken to advanced levels in human stem cells

A new study published in the journal Stem Cell Reports in January 2020 reports the use of an adaptation to a commonly used gene editing technology to achieve a more than 900% increase in efficiency.

30 Jan 2020

New genetic screen for Huntington’s disease

Huntington’s disease is a genetic disease that is debilitating and progressive leading to severe brain damage and eventual death. In patients with this autosomal dominant disease, there is presence of a protein called the Huntingtin protein that forms clumps within the brain leading to the symptoms of the disease.

30 Jan 2020

Scientists discover small molecule that may slow or stop Parkinson's disease progression

A collaboration between scientists at Rutgers University and Scripps Research led to the discovery of a small molecule that may slow down or stop the progression of Parkinson's disease.

30 Jan 2020

Death receptor pathway drives resistance to CAR T cell therapy

Some cancer cells refuse to die, even in the face of powerful cellular immunotherapies like CAR T cell therapy, and new research from the Abramson Cancer Center of the University of Pennsylvania is shedding light on why.

30 Jan 2020

Researchers discover new target for repairing heart after heart attack

Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar.

30 Jan 2020

New target protein linked to regulation, movement of tumor-associated macrophages

Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer owes its notorious identity to the fact that the cancer cells use the host's own immune system to grow and spread, ultimately becoming deadly.

30 Jan 2020

Novel inhibitor to fight metastatic prostate cancer shows promise

When prostate cancer spreads it is often a deadly disease, but now a Stony Brook University-led research team believes a new approach that inhibits a specific fatty acid binding protein (FABP) may be the key to halting disease progression.

30 Jan 2020

New treatment target could change the outlook of patients at risk of kidney injury

Kidney injury is a dreaded complication of commonly performed procedures such as coronary angiography or cardiac surgery, often stopping physicians and patients in their tracks.

30 Jan 2020

Researchers examine abnormal neuron activity in Rett syndrome

The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child matures and key developmental periods pass, the brain becomes less malleable--but certain experiences create opportunities for parts of the adult brain to rewire and learn again.

29 Jan 2020

Researchers identify potential target in the fight against MERS

First identified in 2012, the MERS-coronavirus is capable of causing severe and often fatal pneumonia. There are no effective treatments for MERS.

29 Jan 2020

Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Claudio Franceschi, a world-renowned scientist, professor at the University of Bologna (Italy) and head of the Research Laboratory for Systems Medicine of Healthy Aging at Lobachevsky University, together with other members of an international research team, has described the mechanisms underlying chronic inflammation and identified several risk factors leading to disease.

29 Jan 2020

Maternal consumption of low-calorie sweeteners alters metabolism, gut microbiota in offspring

Many people turn to artificial or so-called natural sweeteners to cut calories and lose weight. A new study led by Dr. Raylene Reimer, PhD, published in the high-impact journal Gut discovered that the consumption of low-calorie sweeteners while pregnant increased body fat in their offspring and disrupted their gut microbiota - the trillions of bacteria and other microorganisms that inhabit the intestinal tract and affect our health and risk of numerous diseases.

29 Jan 2020

Interleukin-1-beta-induced chronic inflammation promotes lung cancer metastasis

The study reveals a detailed epigenetic mechanism for how interleukin-1-beta, a common cytokine that helps fight infections during inflammation, plays a critical role in cancer metastasis.

29 Jan 2020

Link between autism and poor cognition

Autistic people are often brilliant, but they may also have poor cognitive skills. The relationship between autism and either condition, inside the brain, has been far from clear. However, now a new study shows that poor cognition in autism could be due to the influence of a small gene fragment.

29 Jan 2020

Protein C News and Research

New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

Multimodal analysis of tumors could give new insights into treating cancer patients

MSU researcher makes strides in discovering new cellular mechanism

UW creates new integrated center to accelerate development of biomedical discoveries

Potential new biomarker for vascular dementia identified

Turning stink into therapy for atherosclerosis

Gene-editing taken to advanced levels in human stem cells

New genetic screen for Huntington’s disease

Scientists discover small molecule that may slow or stop Parkinson's disease progression

Death receptor pathway drives resistance to CAR T cell therapy

Researchers discover new target for repairing heart after heart attack

New target protein linked to regulation, movement of tumor-associated macrophages

Novel inhibitor to fight metastatic prostate cancer shows promise

New treatment target could change the outlook of patients at risk of kidney injury

Researchers examine abnormal neuron activity in Rett syndrome

Researchers identify potential target in the fight against MERS

Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Maternal consumption of low-calorie sweeteners alters metabolism, gut microbiota in offspring

Interleukin-1-beta-induced chronic inflammation promotes lung cancer metastasis

Link between autism and poor cognition

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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