Protein C News and Research

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Robotic search for drugs that block sperm motility

The hunt for the first male contraceptive pill is on, and scientists at Dundee University may have the needed tool to find it – a robotic screening system.

29 Jan 2020

Pre-existing anticancer drug could help treat common form of heart failure

When it comes to finding new treatments for disease, reinventing the wheel is not always necessary - drugs already in use for other conditions may do the job.

29 Jan 2020

Researchers identify determinant protein for metastasis in alveolar rhabdomyosarcoma

Rhabdomyosarcoma is the most common childhood cancer in the soft tissues, and it is mainly originated in the muscles.

29 Jan 2020

Research uncovers disease-aggravating mutation in mouse model of GRACILE syndrome

The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. This discovery provides a new tool for studies of mitochondrial diseases.

29 Jan 2020

Study uncovers molecular mechanism that triggers a rare type of muscular dystrophy

A study led by the IBB-UAB has identified the molecular mechanism through which a protein, when carrying genetic mutations associated with a rare disease known as limb-girdle muscular dystrophy, type 1G, accelerates its tendency to form amyloid fibrils and finally triggers the appearance of the disease.

29 Jan 2020

New way to treat stroke using an already FDA-approved drug shows promise

Stroke is the third leading cause of death and disability in the United States. More than 87 percent are ischemic strokes, caused by obstruction of one or more cerebral arteries. With limited progress in developing treatments, there is a critical need for neuroprotective agents to effectively treat stroke.

29 Jan 2020

Porvair Sciences offers next generation microplate for phospholipid removal

Porvair Sciences announce Microluteä PLR - a new benchmark product for phospholipid removal. The 96-well microplate provides effective removal (>99%) of phospholipids and proteins with higher levels of reproducibility from plasma and serum samples while maintaining maximum recovery of target analytes.

From Chromatrap® - Porvair Sciences Ltd 29 Jan 2020

New therapeutic strategy to fight against advanced melanoma

Scientists from the Centenary Institute have developed a new therapeutic strategy that could potentially help the fight against advanced-stage melanoma.

29 Jan 2020

New research project aims to slow down the progression of heart failure

A new research project funded by the British Heart Foundation at the University of Manchester aims to find a way to slow down the progression of heart failure.

28 Jan 2020

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

An international research team which includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying the genes and proteins involved in the response to certain harmful bacteria.

28 Jan 2020

Urine protein levels can help identify patients at higher risk for future loss of kidney function

High levels of protein in a patient's urine shortly after an episode of acute kidney injury is associated with increased risk of kidney disease progression, providing a valuable tool in predicting those at highest risk for future loss of kidney function.

28 Jan 2020

Coronavirus death toll in China now 131 with 4,630 cases

Chinese meat markets sell the usual poultry, beef and pork and other forms of meat including rodents, yaks, snakes, tortoises, porcupines etc. With the rising number of people being infected with the novel Corona virus, fingers are pointing towards these small time sellers of unregulated meat that could be carrying the virus.

28 Jan 2020

Novel palladium compound acts against ovarian tumor cells

A group led by a researcher affiliated with the University of São Paulo's São Carlos Chemistry Institute (IQSC-USP) in Brazil has developed a novel palladium compound that acts against ovarian tumor cells without affecting healthy tissues. Palladium is a silvery white metal belonging to the same group as platinum.

28 Jan 2020

Low-protein diet throughout pregnancy and lactation may increase risk of liver damage

A study in rats examines a pathway through which protein deficiency during pregnancy leads to fat accumulation in the liver and increased risk of liver damage.

28 Jan 2020

Scientists may soon be able to prevent disease-spreading mosquitoes from maturing

New research from UC Riverside shows scientists may soon be able to prevent disease-spreading mosquitoes from maturing. Using the same gene-altering techniques, they may also be able help boost reproduction in beneficial bumblebees.

28 Jan 2020

Study finds unexpected response to estrogen at the single cell level

A team led by researchers at Baylor College of Medicine found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as alleles.

28 Jan 2020

An old plant virus inspires the design of novel second-generation malaria vaccine

Scientists from the Walter Reed Army Institute of Research have demonstrated that a novel, second-generation malaria vaccine candidate based on the tobacco mosaic virus may offer protection against Plasmodium falciparum malaria in the upcoming issue of the journal Proceedings of the National Academy of Sciences.

27 Jan 2020

New experimental model developed for 'lipid rafts' in living cells

It is a rather trivial statement: if you want to enter the house through a door, it is best to take a key in your hand, open and go inside. But if you have no idea what the key looks like or where it is hidden - under the doormat, on the basement stairs? - it becomes much more difficult.

27 Jan 2020

New micro-scale technology holds promise for improved tumor diagnosis

Using a single-needle biopsy and new technology for tumor diagnosis developed by Baylor College of Medicine and the Broad Institute of MIT and Harvard, researchers have been able to provide a more detailed and wider window into cancer biology, tumor type and the mechanisms of response and resistance to therapy than with conventional approaches.

27 Jan 2020

Study suggests prenatal origin for ‘young’ Parkinson’s disease

A new study published in the journal Nature Medicine on January 2020 suggests that Parkinson’s disease developing before the age of 50 years could be due to an abnormality in certain brain cells that remains dormant until the age of onset of the disease. It also indicates the potential usefulness of a specific drug to prevent this by correcting the brain cell disorder.

27 Jan 2020