Clinical Trial News and Research

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Exercise training safe in heart failure patients - offer clinical benefit

Exercise training is safe in heart failure patients, does not significantly reduce hospitalization or death, but is associated with several improved clinical outcomes, even in those already receiving optimal medical care, researchers reported at the American Heart Association's Scientific Sessions 2008. The Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) was presented as a late-breaking clinical trial.

11 Nov 2008

Interferon eliminates specific causes of some viruses in heart failure patients, improving clinical outcomes

Giving interferon to heart failure patients with evidence of a chronic viral infection safely eliminated two viruses from their systems and reduced levels of a third virus.

11 Nov 2008

Simple blood test for high-sensitivity C-reactive protein is a useful marker for cardiovascular disease

This year, about 450,000 Americans will die of coronary heart disease – the leading cause of death for both men and women.

11 Nov 2008

National call for cancer trial system to be more responsive to community needs

Addressing the nation's continuing poor performance in cancer clinical trial participation, particularly among racial and ethnic minorities and low income groups, will require meaningful public involvement in the design and implementation of clinical trials, according to a landmark report released today.

11 Nov 2008

Trial of investigational drug for treatment of advanced heart failure

UC San Diego Medical Center is currently enrolling patients in a Phase 2 clinical trial of an investigational drug for the treatment of advanced heart failure.

10 Nov 2008

Researchers test whether cocktail of vitamins and magnesium help prevent hearing loss

About 10 million people in the United States alone—from troops returning from war to students with music blasting through headphones—are suffering from impairing noise-induced hearing loss.

10 Nov 2008

Ewing sarcoma treatment ineffective, despite promising laboratory data

Ewing sarcoma is the second most common type of primary bone cancer seen in children and young adults.

10 Nov 2008

Food allergies are on the rise but effective treatment in the pipeline

Experts in the U.S. say food allergies are on the rise and although strict avoidance is currently the only treatment, new effective therapies are currently being developed.

10 Nov 2008

Gene therapy for advanced heart failure shows promising results

Phase I results of the first clinical trial of gene therapy for patients with advanced heart failure show the approach to be promising, with improvements in several measures of the condition's severity.

10 Nov 2008

Can vitamins and minerals prevent hearing loss?

About 10 million people in the United States alone--from troops returning from war to students with music blasting through headphones--are suffering from impairing noise-induced hearing loss.

10 Nov 2008

Resverlogix Corp shows RVX-208 demonstrates increase in functional HDL particles

Resverlogix Corp. has announced key scientific data was presented in an oral presentation highlighting the novel features of RVX-208 at the American Heart Association Scientific Meeting. The presentation titled "Compound RVX-208 Modulates HDL-C Levels and Function in Non-human Primates and in Early Human Trials" was presented by Dr. Jacques Genest.

10 Nov 2008

NEI releases complete data from age-related eye disease study

The National Eye Institute (NEI), part of the National Institutes of Health (NIH), announces the release of more than 10 years of data collected during the Age-Related Eye Disease Study (AREDS), which looked at the progression of age-related macular degeneration and age-related cataract in 4,757 adults aged 55 to 80.

10 Nov 2008

Medtronic announces U.S. trial data on transcatheter valve for congenital heart disease

Today at the annual scientific sessions of the American Heart Association, the first U.S. clinical trial data on the Melody transcatheter pulmonary valve were presented. These findings also represent the first U.S. data on transcatheter valves in a population with congenital heart disease and the first reported U.S. data on the use of a transcatheter valve in the pulmonary position. The Melody valve is currently investigational in the U.S.

10 Nov 2008

New risk factor for heart disease suggests more should be on statins

Canadian scientists have discovered a new risk factor for cardiovascular disease and the significance of their discovery was so conclusive that the clinical trial was stopped before its scheduled completion date.New risk factor for heart disease suggests more should be on statins

10 Nov 2008

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

VIA Pharmaceuticals, Inc. has announced the results of two Phase 2 studies of its lead drug, VIA-2291.

10 Nov 2008

High levels of high-sensitivity C-reactive protein found to be new risk factor for cardiovascular disease

A team of international researchers - including scientists from the McGill University Health Centre (MUHC) and McGill University - have discovered that having high levels of particular protein puts patients at increased risk of developing cardiovascular disease.

10 Nov 2008

Stents no help for patients with narrow kidney arteries

Using stents to open up kidney arteries is commonly done in patients with atherosclerotic renovascular disease, but the procedure provides no benefit, according to a paper being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

10 Nov 2008

Spherix starts patient recruitment in India for phase 3 diabetes trial

Spherix Incorporated reported that patient recruitment for its Phase 3 clinical trial of its potential type 2 diabetes drug, Naturlose, has begun in India. Expectations for India are to provide more than 300 patients spread across 35 sites for the pivotal Phase 3 trial.

8 Nov 2008

Behavioral therapy helps overcome depression in kidney disease patients on dialysis

Depression is common among individuals on dialysis for kidney disease, but behavioral therapy can significantly improve their quality of life, according to a paper being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

8 Nov 2008

Sunesis Pharmaceuticals presents data of Voreloxin in patients with acute myeloid leukemia and ovarian cancer

Sunesis Pharmaceuticals, Inc. presented data from three clinical trials of the company's lead drug candidate, voreloxin (formerly SNS-595), at the Chemotherapy Foundation Symposium held in New York on November 4-8.

7 Nov 2008

Clinical Trial News and Research

Exercise training safe in heart failure patients - offer clinical benefit

Interferon eliminates specific causes of some viruses in heart failure patients, improving clinical outcomes

Simple blood test for high-sensitivity C-reactive protein is a useful marker for cardiovascular disease

National call for cancer trial system to be more responsive to community needs

Trial of investigational drug for treatment of advanced heart failure

Researchers test whether cocktail of vitamins and magnesium help prevent hearing loss

Ewing sarcoma treatment ineffective, despite promising laboratory data

Food allergies are on the rise but effective treatment in the pipeline

Gene therapy for advanced heart failure shows promising results

Can vitamins and minerals prevent hearing loss?

Resverlogix Corp shows RVX-208 demonstrates increase in functional HDL particles

NEI releases complete data from age-related eye disease study

Medtronic announces U.S. trial data on transcatheter valve for congenital heart disease

New risk factor for heart disease suggests more should be on statins

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

High levels of high-sensitivity C-reactive protein found to be new risk factor for cardiovascular disease

Stents no help for patients with narrow kidney arteries

Spherix starts patient recruitment in India for phase 3 diabetes trial

Behavioral therapy helps overcome depression in kidney disease patients on dialysis

Sunesis Pharmaceuticals presents data of Voreloxin in patients with acute myeloid leukemia and ovarian cancer

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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