Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Thomson Reuters names Sanford-Burnham cancer researcher among 2012 Citation Laureates

Thomson Reuters has selected Erkki Ruoslahti, M.D., Ph.D., cancer researcher and distinguished professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham), as one of its 2012 Citation Laureates. Citation Laureates are scientists that Thomson Reuters has predicted to win the Nobel Prize.

24 Sep 2012

Children with mild to moderate kidney disease have carotid atherosclerosis

A federally funded study led by researchers at Johns Hopkins Children's Center has found that children with mild to moderate kidney disease have abnormally thick neck arteries, a condition known as carotid atherosclerosis, usually seen in older adults with a long history of elevated cholesterol and untreated hypertension.

21 Sep 2012

Early menopause increases cardiovascular risk

Women who reach the menopause early have a doubled risk for coronary heart disease and stroke, study findings show.

20 Sep 2012

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Obese adults with excess visceral fat (fat located inside the abdominal cavity, around the body's internal organs) and biomarkers of insulin resistance had an associated increased risk for the development of type 2 diabetes mellitus, while obese individuals with higher amounts of total body fat and subcutaneous fat (underneath the skin) did not have this increased risk, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

20 Sep 2012

Women with early menopause more likely to develop coronary heart disease and stroke

Women who go into early menopause are twice as likely to suffer from coronary heart disease and stroke, new Johns Hopkins-led research suggests. The association holds true in patients from a variety of different ethnic backgrounds, the study found, and is independent of traditional cardiovascular disease risk factors, the scientists say.

19 Sep 2012

Wake Forest Baptist to identify genetic variants associated with premature cardiovascular disease

Researchers at Wake Forest Baptist Medical Center are leading a four-year, $8.9 million national project to identify variations in the human genome and corresponding changes in the arterial proteins associated with premature development of atherosclerosis.

15 Sep 2012

Resuscitation after cardiac arrest: an interview with Zach Goldberger

Cardiac arrest is an important clinical challenge. The event is unexpected and surprising; the patients are challenging, and the outcomes are poor.

13 Sep 2012

MicroRNA-145 gene therapy can drastically reduce severity and progression of atherosclerosis

Researchers at St. Michael's Hospital are one step closer to understanding why plaque bursts in coronary arteries and causes heart attacks.

11 Sep 2012

Increased risk of heart failure and cardiovascular death linked to thickening of heart's right ventricle

Researchers at the Perelman School of Medicine at the University of Pennsylvania report in a new study that thickening of the heart's right ventricle is associated with an increased risk of heart failure and cardiovascular death in patients without clinical cardiovascular disease at baseline. The study is published online ahead of print in the journal Circulation.

7 Sep 2012

Unrecognized heart attack prevalent in older diabetes patients

The prevalence of unrecognized myocardial infarction by cardiac magnetic resonance in elderly patients is higher than that of recognized MI and is associated with increased mortality, say researchers.

7 Sep 2012

Hebrew University researcher develops anti-inflammatory and anti-allergic family of drugs

A synthetic, anti-inflammatory and anti-allergic family of drugs to combat a variety of illnesses while avoiding detrimental side effects has been developed by a Hebrew University of Jerusalem researcher.

7 Sep 2012

UC Davis plans to open West Coast Metabolomics Center

With a $9.3 million startup grant from the National Institutes of Health, the University of California, Davis, has announced plans to open the West Coast Metabolomics Center, a high-tech consortium of research and service laboratories that will help scientists better understand and develop more effective treatments for complex diseases like diabetes, cancer and atherosclerosis.

6 Sep 2012

Exposure to perfluorooctanoic acid appears to increase risk of CVD and peripheral arterial disease

Exposure to perfluorooctanoic acid (PFOA), a manmade chemical used in the manufacture of some common household products, appears to be associated with cardiovascular disease and peripheral arterial disease in a study of 1,216 individuals, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.

4 Sep 2012

Researchers identify several genetic factors linked to C-reactive protein

African Americans have higher blood levels of a protein associated with increased heart-disease risk than European Americans, despite higher "good" HDL cholesterol and lower "bad" triglyceride levels. This contradictory observation now may be explained, in part, by a genetic variant identified in the first large-scale, genome-wide association study of this protein involving 12,000 African American and Hispanic American women.

31 Aug 2012

Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

Patients with uncontrolled renovascular hypertension saw a significant improvement in their blood pressure with renal artery stent deployment. The multicenter HERCULES trial, evaluating the safety and effectiveness of the RX Herculink Elite Stent, found that patients with higher blood pressure levels at baseline had the most dramatic reduction in blood pressure following intervention.

31 Aug 2012

Scientists decode signals that boost the burning of fat

The numbers of obese people are climbing steeply all over the world - with obvious major consequences for their health. Due to excess food intake and a lack of physical activity, but also due to genetic factors, the risk for overweight people dying from diseases like coronary heart disease, diabetes und atherosclerosis increases.

29 Aug 2012

Resverlogix enters $25 million Loan Agreement with Citibank

Resverlogix Corp. today announced that it has entered into a $25 million Loan Agreement with Citibank, N.A.. Resverlogix received the $25 million upon closing of the loan.

28 Aug 2012

Insulin glargine retards progression of atherosclerosis in high-risk people

A sub-study of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial, designed to investigate the effect of insulin glargine and omega-3 fatty acids on atherosclerosis progression, has found that, compared to standard care, only insulin glargine (a long-acting insulin) had a "modest" statistically non-significant reducing effect on the primary outcome of rate of change in maximum carotid intima media thickness (CIMT) at 12 carotid sites.

27 Aug 2012

Patients with psoriasis are at high risk of new-onset diabetes mellitus

Patients with psoriasis are at high risk of new-onset diabetes mellitus, according to research presented at ESC Congress 2012.

27 Aug 2012

Mexican-Americans with ancestral links have higher insulin resistance levels

Mexican-Americans with an ancestral link to Amerindian tribes were found to have higher insulin resistance levels, which is an indication of several chronic conditions such as type 2 diabetes, according to research by The University of Texas Health Science Center at Houston (UTHealth).

26 Aug 2012

Atherosclerosis News and Research

Further Reading

Thomson Reuters names Sanford-Burnham cancer researcher among 2012 Citation Laureates

Children with mild to moderate kidney disease have carotid atherosclerosis

Early menopause increases cardiovascular risk

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Women with early menopause more likely to develop coronary heart disease and stroke

Wake Forest Baptist to identify genetic variants associated with premature cardiovascular disease

Resuscitation after cardiac arrest: an interview with Zach Goldberger

MicroRNA-145 gene therapy can drastically reduce severity and progression of atherosclerosis

Increased risk of heart failure and cardiovascular death linked to thickening of heart's right ventricle

Unrecognized heart attack prevalent in older diabetes patients

Hebrew University researcher develops anti-inflammatory and anti-allergic family of drugs

UC Davis plans to open West Coast Metabolomics Center

Exposure to perfluorooctanoic acid appears to increase risk of CVD and peripheral arterial disease

Researchers identify several genetic factors linked to C-reactive protein

Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

Scientists decode signals that boost the burning of fat

Resverlogix enters $25 million Loan Agreement with Citibank

Insulin glargine retards progression of atherosclerosis in high-risk people

Patients with psoriasis are at high risk of new-onset diabetes mellitus

Mexican-Americans with ancestral links have higher insulin resistance levels

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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