Cell Death News and Research

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Study reveals molecular causes of brain asymmetry

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are "right-brained" while others are "left-brained."

15 Apr 2020

Tumors commandeer cell death pathway to avoid immune system attack after radiation

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests.

13 Apr 2020

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Many cancers can be successfully treated, but treatment itself often comes with risks as well. Cancer therapy that uses anthracyclines--a class of commonly used chemotherapy drugs--has been associated with heart damage that can eventually result in heart failure. It is thought to be the reason why heart disease is a leading cause of death in cancer survivors, immediately following cancer recurrence.

9 Apr 2020

Improper cellular cleanup during neurodevelopment may cause lifelong behavioral issues

Improper removal of faulty brain cells during neurodevelopment may cause lifelong behavioral issues, new research from the University of Virginia School of Medicine suggests.

9 Apr 2020

World's largest protein connection map reveals cell workings

The human body is comprised of billions of cells. Yet it functions and grows as a single organism, because of trillions of interactions that help various cells recognize and respond to each other via different molecules on their surface or inside the cells. Now, a new study published in the journal Nature in April 2020 describes the first-ever interactome map, to help distinguish healthy interactions and disease-producing ones.

8 Apr 2020

World's largest map of protein connections holds clues to health and disease

Scientists have described the first reference map of interactions between gene-encoded proteins which make up cells.

8 Apr 2020

Researchers develop a unique radiochemical synthesis approach for treating cancer

Radiolabeled molecules, so-called radiotracers, help nuclear physicians to detect and precisely target tumors, which are often developing due to pathological changes in metabolic processes.

7 Apr 2020

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Human cells respond to stresses like DNA damage, metabolic imbalance and starvation by first trying to repair the problem.

5 Apr 2020

Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis

A new study from Columbia University Irving Medical Center and the Herbert Irving Comprehensive Cancer Center suggests a compound in development for a rare kidney stone disease may have potential against pancreatic cancer.

2 Apr 2020

Stem cells used to combat COVID-19 pneumonia

The novel coronavirus first emerged in December 2019, and since then, it rippled across 180 countries, affecting hundreds of thousands of people. Amid the coronavirus disease (COVID-19) pandemic, many people are looking for answers. Scientists are racing to find a treatment that can help save lives. Now, a team of scientists has suggested that stem cell therapy can help fight the deadly infection.

1 Apr 2020

Scientists unravel a new mechanism that triggers cell death and inflammation

Z-form nucleic acids are double-stranded DNA and RNA molecules with an unusual left-handed double helix structure, as opposed to the classical right-handed Watson-Crick double helix. Z-nucleic acids were discovered more than 40 years ago, but their biological function has remained poorly understood.

31 Mar 2020

Combination of exercise and cell-aging drug could help people with chronic inflammatory myopathy

Exercise can only improve strength in muscle-degenerating diseases when a specific type of muscle cell ages, report a Hokkaido University researcher and colleagues with Sapporo Medical University in Japan. Their findings utilizing mice models were published in the journal Nature Communications.

31 Mar 2020

Moffitt scientists identify potential therapeutic targets for cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cuSCC) is the second most common diagnosed malignancy in the United States, with approximately 700,000 new cases each year.

30 Mar 2020

Research could open up new therapeutic strategies for some lung and kidney cancers

New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).

30 Mar 2020

Weakness in lung and kidney cancer cells could serve as therapeutic target

An important discovery about how some cancers rely on glucose to survive could lead to development of tumor-specific treatments.

30 Mar 2020

New in vivo priming strategy can be an effective means to enhance cardiac repair

Human stem cells have been regarded as one of the promising cell sources for cardiac regeneration therapy.

27 Mar 2020

New approach shows promise as a treatment for chemo-resistant ovarian cancer

Researchers have made a discovery about the behavior of ovarian cancer cells that could lead to a new treatment approach.

27 Mar 2020

Scientists uncover key molecular mechanism underlying different aspects of sepsis

Sepsis is a life-threatening condition that kills millions annually; it is poorly understood and has no specific treatment.

27 Mar 2020

Experimental heart disease drug may treat chemo-resistant ovarian cancer

Most ovarian cancer starts in fallopian tubes. Then it sloughs from its site of origin and floats around in fluid until finding new sites of attachment. It's not easy for cancer cells to survive away from their moorings.

26 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Cell Death News and Research

Study reveals molecular causes of brain asymmetry

Tumors commandeer cell death pathway to avoid immune system attack after radiation

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Improper cellular cleanup during neurodevelopment may cause lifelong behavioral issues

World's largest protein connection map reveals cell workings

World's largest map of protein connections holds clues to health and disease

Researchers develop a unique radiochemical synthesis approach for treating cancer

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis

Stem cells used to combat COVID-19 pneumonia

Scientists unravel a new mechanism that triggers cell death and inflammation

Combination of exercise and cell-aging drug could help people with chronic inflammatory myopathy

Moffitt scientists identify potential therapeutic targets for cutaneous squamous cell carcinoma

Research could open up new therapeutic strategies for some lung and kidney cancers

Weakness in lung and kidney cancer cells could serve as therapeutic target

New in vivo priming strategy can be an effective means to enhance cardiac repair

New approach shows promise as a treatment for chemo-resistant ovarian cancer

Scientists uncover key molecular mechanism underlying different aspects of sepsis

Experimental heart disease drug may treat chemo-resistant ovarian cancer

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics