Protein C News and Research

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'Methylation clock' gene found to have functional role in aging of the eye

A lengthy-named gene called Elongation of Very Long Chain Fatty Acids Protein 2 or ELOVL2 is an established biomarker of age.

16 Jan 2020

Essential tremor caused by overactive brain waves

The source of essential tremor--a movement disorder that causes involuntary trembling of the hands, arms, and head--has been enigmatic, impeding the development of effective treatments for a condition that affects 4% of people over 40.

16 Jan 2020

Study reveals overactive brain wave activity as an underlying cause of essential tremor

Researchers at Columbia University Irving Medical Center say that overactive brainwave activity is the underlying cause of essential tremor – a common movement disorder that causes involuntary rhythmic shaking in around 4% of people aged over 40.

16 Jan 2020

BPA activates immune response in mice that persists for at least three generations

Some plastic food and beverage containers still contain bisphenol A, which can mimic the hormone estrogen. Although experts say that small amounts of BPA detected in foods are unlikely to cause problems, some people worry that constant low-level exposures could have health effects, especially for developing fetuses, infants and children.

16 Jan 2020

Study shows superior functionality of Duodenum Intestine-Chip populated with organoids

Emulate, Inc. announced today a published study in collaboration with Johns Hopkins University School of Medicine, that demonstrated superior functionality of the Duodenum Intestine-Chip populated with organoids, compared to organoids alone.

14 Jan 2020

Princeton researchers uncover vital role played by a protein elevated in many cancers

Researchers at Princeton University have successfully recreated a key process involved in cell division in a test tube, uncovering the vital role played by a protein that is elevated in over 25% of all cancers.

14 Jan 2020

Parkinson’s disease could be prevented by gut microbes

One common gut organism that helps us digest food better could also be a powerful instrument in preventing or reversing the symptoms of Parkinson’s disease (PD), according to a recent study. The changes are due to the ability of this bacterium to delay the build-up of a toxic protein involved in this in the disease condition, or even to eliminate the toxin altogether.

14 Jan 2020

Protein SV2A levels could explain poor neuronal connections in schizophrenia

A team of researchers have found that persons with schizophrenia may have lower levels of certain specific proteins that show up on their brain scans. This could help as diagnostic tools, say experts. The new study titled, “Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats”, is published in the latest issue of the journal Nature Communications.

14 Jan 2020

Study reveals how clotting protein and blood platelets promote immune evasion, tumor progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer.

14 Jan 2020

Biomaterial-based vaccine has potential to completely eliminate AML cells

Acute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherapy has been the standard AML treatment for over 40 years, and while it often causes the cancer to go into remission, it rarely completely eliminates the cancerous cells, which then lead to disease recurrence in nearly half of treated patients.

14 Jan 2020

Bath scientists identify promising route to develop new treatments for skin cancer

A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumor growth.

14 Jan 2020

Research suggests a new role for neurogenesis

The ability to create new neurons may exist as built-in protection for sensitive brain areas, according to research in mice recently published in JNeurosci.

From Society for Neuroscience 14 Jan 2020

Gut bacteria could protect against Parkinson’s, research suggests

A common bacteria that boosts digestive health can slow – and even reverse – build-up of a protein associated with Parkinson’s, new research suggests.

14 Jan 2020

Study uncovers how rice blast fungus uses its own cell wall to launch an attack

In response to environmental changes and nutrient starvation, cells are known to undergo extreme alterations. This includes switching from one type to another (“differentiation”) and changes in metabolic pathways (“metabolic switching”).

14 Jan 2020

Boehringer Ingelheim and Enleofen partner to develop anti-IL-11 therapies for multiple fibrotic disorders

Boehringer Ingelheim and Enleofen Bio Pte. Ltd. announced today the acquisition of worldwide exclusive rights to Enleofen’s preclinical interleukin-11 (IL-11) platform by Boehringer Ingelheim to develop first-in-class therapies across a broad range of fibro-inflammatory diseases.

From Boehringer Ingelheim International GmbH 14 Jan 2020

Researchers find key to preventing muscular dystrophy-related heart disease

A Rutgers-led team may have found the key to preventing Duchenne muscular dystrophy (DMD)-related heart disease, the leading cause of death in patients living with the disease.

14 Jan 2020

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Daltonics 14 Jan 2020

NAU scientists in search of a powerful combination of melanoma-fighting drugs

Melanoma is the most lethal type of skin cancer and unusually common in Arizona, where residents are exposed to higher-than-average amounts of ultraviolet radiation.

13 Jan 2020

The circadian clock is key to reducing radiation‐induced cardiotoxicity

Treatment for breast cancer commonly includes radiation therapy, which offers good chances of success but comes with a serious long-term side effect: toxicity due to radiation that reaches the heart, causing DNA damage in healthy heart cells. Over time, this can lead to heart disease and eventually heart failure.

13 Jan 2020

New study sheds light on storage and retrieval of hardwired long-term memory

Storing and retrieving memories is among the most important tasks our intricate brains must perform, yet how that happens at a molecular level remains incompletely understood.

13 Jan 2020