Immune System News and Research

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Interim results from Bristol-Myers Squibb’s BMS-936558 Phase 1 study on NSCLC, MM and RCC

Bristol-Myers Squibb Company today announced interim results from the expanded Phase 1 dose-ranging study 003 (n=296) of its investigational anti-PD-1 immunotherapy (BMS-936558), which showed clinical activity in patients with previously-treated non small-cell lung cancer (NSCLC), metastatic melanoma and renal cell carcinoma (RCC).

4 Jun 2012

Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Two clinical trials led by Johns Hopkins Kimmel Cancer Center researchers in collaboration with other medical centers, testing experimental drugs aimed at restoring the immune system's ability to spot and attack cancer, have shown promising early results in patients with advanced non-small cell lung cancer, melanoma, and kidney cancer.

2 Jun 2012

Reumofan Plus may have harmful pharmaceutical ingredients, warns FDA

The U.S. Food and Drug Administration is warning consumers that Reumofan Plus, marketed as a "natural" dietary supplement for pain relief and other serious conditions, contains several active pharmaceutical ingredients not listed on the label that could be harmful.

2 Jun 2012

Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer

Investigators at The Cancer Institute of New Jersey (CINJ) have partnered with the National Cancer Institute (NCI) and launched a clinical trial examining the effectiveness of a combined vaccine and hormone treatment for prostate cancer that is resistant to hormone therapy and not visible on imaging tests such as a CT scan and a bone scan.

2 Jun 2012

Electronic nose and optoacoustics improve diagnosis of prostate cancer

Chances of survival of prostate cancer depend strongly on the stage at which the disease is diagnosed. Now scientists have developed new methods relying on an electronic nose and optoacoustics to improve the diagnosis techniques and avoid fatal treatment delays

2 Jun 2012

First study to correlate dietary fiber intake with inflammatory markers in adolescents

Adolescents who don't eat enough fiber tend to have bigger bellies and higher levels of inflammatory factors in their blood, both major risk factors for cardiovascular disease and diabetes, researchers report.

2 Jun 2012

Breakthrough in nanotechnology could make laboratory tests more sensitive

A laboratory test used to detect disease and perform biological research could be made more than 3 million times more sensitive, according to researchers who combined standard biological tools with a breakthrough in nanotechnology.

2 Jun 2012

Smoke from cooking fires associated with cognitive deficits in children

Children exposed to open-fire cooking in developing countries experience difficulty with memory, problem-solving and social skills, according to researchers at the University of California, Riverside and Pitzer College in Claremont, Calif.

2 Jun 2012

Skin transplants benefit vitiligo patients

Patients with the skin disease vitiligo may benefit from surgery in which skin cells from unaffected areas of the body are transplanted into damaged areas to restore color, say researchers.

1 Jun 2012

Glucocorticoid steroids in intelligent medicine specifically hits relevant cells

Scientists at Aarhus University, Denmark in collaboration with the biotech company Cytoguide now publish a key to use glucocorticoid steroids in a kind of intelligent medicine that specifically hits the relevant cells. Data are based on rodent studies but if this principle is translated to humans it may greatly improve todays hazardous treatment with this type of potent steroids.

1 Jun 2012

Inexpensive paper-based device warns about unhealthy levels of airborne metals

Scientists are reporting development of a new paper-based device that can warn workers that they are being exposed to potentially unhealthy levels of airborne metals almost immediately, instead of the weeks required with current technology. The report on the device, which costs about one cent to make and could prevent illness in the millions of people who work with metal, appears in ACS' journal Analytical Chemistry.

1 Jun 2012

NYUCD receives NIH grant for ‘Biomarkers of Periodontal Disease Progression’ project

New York University College of Dentistry has been selected as one of five institutions that are sharing a $20.7 million grant from the National Institute of Dental and Craniofacial Research (NIH) to the Forsyth Institute to find new ways to diagnose and fight periodontal disease.

1 Jun 2012

Seriously ill children administered zinc in addition to antibiotics respond better, more quickly to treatment, study shows

"In a newly released clinical study, conducted in India" and published in the Lancet on Thursday, "hundreds of seriously ill infants who received zinc -- an essential micronutrient for the immune system and human growth -- as well as antibiotics, responded better and more quickly to treatment than those who did not," IRIN reports.

1 Jun 2012

Foreign-born populations in the U.S. are at increased risk for chronic HBV

The prevalence of chronic hepatitis B virus (HBV) infection in the U.S. may be as high as 2.2 million cases according to a new study now available in Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

1 Jun 2012

LILRB2 receptor plays an important role in keeping stem cells from differentiating

An immune-system receptor plays an unexpected but crucially important role in keeping stem cells from differentiating and in helping blood cancer cells grow, researchers at UT Southwestern Medical Center report today in the journal Nature.

1 Jun 2012

Scientists discover SL9266 'switch' in the Hepatitis C virus

Scientists have discovered a 'switch' in the Hepatitis C virus which could be used as a target for new kinds of drug treatment.

1 Jun 2012

Researchers uncover potential new way to regulate the body's natural immune response

Australian researchers have uncovered a potential new way to regulate the body's natural immune response, offering hope of a simple and effective new treatment for auto-immune diseases.

1 Jun 2012

Clove oil could cause an allergic skin reaction

McCord Research the parent company of Pinnaclife warns consumers that fruit that is protected from infestation or bacteria by an ingredient as common as clove oil could cause an allergic skin reaction.

1 Jun 2012

Einstein receives NIH grant to create new vaccine against TB

The National Institutes of Health (NIH) has awarded researchers at Albert Einstein College of Medicine at Yeshiva University a five-year, $5.9 million grant to develop a new vaccine against tuberculosis (TB), including the toughest-to-treat forms of the disease known as multi drug-resistant and extensively drug-resistant. The grant will build on a new approach to TB vaccine design that is based on genetically altered Mycobacterium smegmatis, which is closely related to the bacterial species (Mycobacterium tuberculosis) that causes TB in humans.

1 Jun 2012

suPAR protein can serve as marker for blood poisoning

Blood poisoning is a serious problem in medical care. Research from Malmö University in Sweden now shows that the protein suPAR, which can be used for early detection of critical cases of sepsis, is found in saliva, which opens new potential for tracking diseases.

1 Jun 2012

Immune System News and Research

Interim results from Bristol-Myers Squibb’s BMS-936558 Phase 1 study on NSCLC, MM and RCC

Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Reumofan Plus may have harmful pharmaceutical ingredients, warns FDA

Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer

Electronic nose and optoacoustics improve diagnosis of prostate cancer

First study to correlate dietary fiber intake with inflammatory markers in adolescents

Breakthrough in nanotechnology could make laboratory tests more sensitive

Smoke from cooking fires associated with cognitive deficits in children

Skin transplants benefit vitiligo patients

Glucocorticoid steroids in intelligent medicine specifically hits relevant cells

Inexpensive paper-based device warns about unhealthy levels of airborne metals

NYUCD receives NIH grant for ‘Biomarkers of Periodontal Disease Progression’ project

Seriously ill children administered zinc in addition to antibiotics respond better, more quickly to treatment, study shows

Foreign-born populations in the U.S. are at increased risk for chronic HBV

LILRB2 receptor plays an important role in keeping stem cells from differentiating

Scientists discover SL9266 'switch' in the Hepatitis C virus

Researchers uncover potential new way to regulate the body's natural immune response

Clove oil could cause an allergic skin reaction

Einstein receives NIH grant to create new vaccine against TB

suPAR protein can serve as marker for blood poisoning

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