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Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

New analysis shows how convalescent plasma can be used as effective, low-cost COVID-19 treatment

Three years into the COVID-19 pandemic, new variant outbreaks continue to fuel economic disruptions and hospitalizations across the globe.

22 Feb 2023

Challenges associated with prescribing exercise to diabetic patients taking metformin

In a recent study published in the Sports Medicine and Health Science journal, researchers assessed the impact of exercise precision medicine on type 2 diabetes.

21 Feb 2023

Research identifies potential treatment target for infantile spasms syndrome

New research from Tufts University School of Medicine and the Graduate School of Biomedical Sciences suggests that the timing of the death of certain inhibitory neurons in the brain shortly after birth may be at least partly to blame for infantile spasms syndrome (ISS), a rare but devastating form of epilepsy that develops most frequently between four and eight months of age but can emerge within weeks of birth until ages 4 or 5.

21 Feb 2023

Alternative splicing plays a role in compensating for loss of gene function

Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.

21 Feb 2023

University of Ottawa physician becomes first Canadian winner of the AFMC Wellness Award

The University of Ottawa's Dr. Mamta Gautam is the first awardee of the AFMC Wellness Award, a new national honor that recognizes an individual in Canada who has shown dedication to the promotion and advancement of the wellness of physicians, medical students, and others.

21 Feb 2023

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

A long-acting antiretroviral treatment (LA-ART) given every four to eight weeks, and delivered with comprehensive support services, suppressed HIV in people who were previously not virologically suppressed.

21 Feb 2023

Medicaid expansion may improve outcomes for children with cancer

Medicaid expansion may improve outcomes for children with cancer, finds a new analysis from the Brown School and Washington University School of Medicine in St. Louis.

21 Feb 2023

Cleveland Clinic researchers receive $3.14 million NIH grant to use “digital twins” for reducing healthcare disparities

Supported by a new $3.14 million grant from the National Institutes of Health to Cleveland Clinic, researchers are using an emerging technology known as "digital twins" to better understand healthcare disparities based on where someone lives.

21 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

21 Feb 2023

Skin medication shows promise in treating alcohol use disorder

Researchers from Oregon Health & Science University and institutions across the country have identified a pill used to treat a common skin disease as an "incredibly promising" treatment for alcohol use disorder.

21 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

First molecular biomarker for acquired generalized lipodystrophy discovered

Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.

21 Feb 2023

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects' nerve cells that are able to fine-tune their ability to detect particularly "welcoming" odors in human skin.

21 Feb 2023

Review: Latest findings in the spina bifida-related care of many comorbidities

Open spina bifida (SB), a neural tube defect (NTD), also known as myelomeningocele, remains the most complex congenital abnormality of the central nervous system compatible with long term survival.

21 Feb 2023

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Researchers from Children's Hospital of Philadelphia (CHOP) developed two new zebrafish models for studying a specific genetic form of mitochondrial disease that represents the most common cause of Leigh syndrome.

21 Feb 2023

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

The Oxford-Harrington Rare Disease Centre, a partnership of the University of Oxford and Harrington Discovery Institute at University Hospitals, is hosting a virtual event on Monday, Feb. 27, 2023, in honor of the upcoming Rare Disease Day, which is celebrated across the globe on February 28 every year.

21 Feb 2023

Black patients more likely to experience premature arteriovenous graft failure after dialysis maintenance

Compared to other races, African American patients are more likely to experience premature arteriovenous (AV) graft failure in the treatment of advanced kidney failure, according to a study published today in Radiology, a journal of the Radiological Society of North America.

21 Feb 2023

Medicine News and Research

Dietary polyphenols may play a role in regulating inflammatory immune responses

New analysis shows how convalescent plasma can be used as effective, low-cost COVID-19 treatment

Challenges associated with prescribing exercise to diabetic patients taking metformin

Research identifies potential treatment target for infantile spasms syndrome

Alternative splicing plays a role in compensating for loss of gene function

University of Ottawa physician becomes first Canadian winner of the AFMC Wellness Award

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

Medicaid expansion may improve outcomes for children with cancer

Cleveland Clinic researchers receive $3.14 million NIH grant to use “digital twins” for reducing healthcare disparities

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Skin medication shows promise in treating alcohol use disorder

Step-by-step process of rewiring cells to generate germ cell precursors

First molecular biomarker for acquired generalized lipodystrophy discovered

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

Review: Latest findings in the spina bifida-related care of many comorbidities

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

Black patients more likely to experience premature arteriovenous graft failure after dialysis maintenance

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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