Protein C News and Research

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Researchers develop new way to fight late-stage sepsis

Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body's extreme reaction to infection.

6 Jan 2020

Whole exome sequencing routinely fails to adequately analyze large segments of DNA

Children who undergo expansive genetic sequencing may not be getting the thorough DNA analysis their parents were expecting, say experts at UT Southwestern Medical Center.

6 Jan 2020

Researchers show new potential path to improve bone-repair procedures

Researchers are moving closer to a new approach for improving spinal fusion procedures and repairing broken or defective bones that avoids an over-production of bone that commonly occurs in current treatments.

3 Jan 2020

Study shows the feasibility of using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy.

3 Jan 2020

New radiotracer can provide insights into how the heart recovers after myocardial infarction

Insights into how the heart recovers after myocardial infarction (heart attack) can be obtained with a new radiotracer that targets fibroblast activity prior to it causing permanent damage.

2 Jan 2020

Measuring glycans in samples of antibodies

When Lorna De Leoz invited laboratories to participate in her glycomics study, she hoped for 20 responses. Instead, she was deluged by emails from around the world.

2 Jan 2020

Researchers discover how c-Cbl protein modulates tumor growth

Immune checkpoints are surface proteins that cancer cells use to evade immune response. These surface proteins are critical for cancer cell growth and drugs targeting these proteins have revolutionized the management of patients with a wide array of cancers.

2 Jan 2020

Researchers move closer to identifying leukemic stem cells

Acute myeloid leukemia is the most common type of leukemia in adults. It is characterized by the pathological expansion of immature cells (myeloblasts) that invade the bone marrow and expand into the blood, affecting the production of the rest of the healthy cells.

2 Jan 2020

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Promega announce license agreement with MilliporeSigma, a leader in genome editing, to access MilliporeSigma’s foundational CRISPR genome-editing technology.

From Promega Corporation 2 Jan 2020

Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

Ariel Louwrier discusses the development of pre-formed tau and alpha-synuclein fibrils for research into Alzheimer's and Parkinson's disease.

From StressMarq Biosciences Inc. 2 Jan 2020

Protein therapy could improve outcomes following heart attack, study shows

Heart disease remains the largest killer in Australia and around the world. A new study has shown that a protein therapy- recombinant human platelet-derived growth factor-AB (rhPDGF-AB) - could improve outcomes following heart attack.

2 Jan 2020

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid "plaques," which have been the focus of Alzheimer's research and drug development for decades, was found to be of little utility in predicting how damage would unfold as the disease progressed.

2 Jan 2020

Obj-SCD predicts future amyloid accumulation and neurodegeneration

Writing in the December 30, 2019 online issue of Neurology, researchers at University of California San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report that accumulating amyloid -- an abnormal protein linked to neurodegenerative conditions such as Alzheimer's disease -- occurred faster among persons deemed to have "objectively-defined subtle cognitive difficulties" (Obj-SCD) than among persons considered to be "cognitively normal."

31 Dec 2019

New dementia vaccine may proceed to clinical trials after successful testing

A preventive treatment for dementia may proceed to clinical trials after successful animal testing.

31 Dec 2019

Amyloid plaques may not necessarily come first in Alzheimer's disease, suggests new study

The scientific community has long believed that beta-amyloid, a protein that can clump together and form sticky plaques in the brain, is the first sign of Alzheimer's disease. Beta-amyloid then leads to other brain changes including neurodegeneration and eventually to thinking and memory problems. But a new study challenges that theory.

30 Dec 2019

Pulmonary fibrosis associated with short and long sleep duration

Scientists have discovered that people who regularly sleep for more than 11 hours or less than 4 hours are 2-3 times more likely to have the incurable disease, pulmonary fibrosis, compared to those that sleep for 7 hours in a day. They attribute this association to the body clock.

30 Dec 2019

Study provides better understanding of mechanisms that limit cilia number in cells

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes.

30 Dec 2019

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

A new deep learning approach to predict disease-associated mutations

During the past years, artificial intelligence (AI) -- the capability of a machine to mimic human behavior -- has become a key player in high-techs like drug development projects.

28 Dec 2019

Study uncovers key protein that supports the growth of many colorectal cancers

Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers.

28 Dec 2019

Protein C News and Research

Researchers develop new way to fight late-stage sepsis

Whole exome sequencing routinely fails to adequately analyze large segments of DNA

Researchers show new potential path to improve bone-repair procedures

Study shows the feasibility of using gene therapy to treat chronic traumatic encephalopathy

New radiotracer can provide insights into how the heart recovers after myocardial infarction

Measuring glycans in samples of antibodies

Researchers discover how c-Cbl protein modulates tumor growth

Researchers move closer to identifying leukemic stem cells

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

Protein therapy could improve outcomes following heart attack, study shows

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Obj-SCD predicts future amyloid accumulation and neurodegeneration

New dementia vaccine may proceed to clinical trials after successful testing

Amyloid plaques may not necessarily come first in Alzheimer's disease, suggests new study

Pulmonary fibrosis associated with short and long sleep duration

Study provides better understanding of mechanisms that limit cilia number in cells

Scientists discover potential drug compounds that target common type of liver cancer

A new deep learning approach to predict disease-associated mutations

Study uncovers key protein that supports the growth of many colorectal cancers

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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