Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Study addresses important early risk factors of cardiovascular health in adolescents

Early exposure to tobacco smoke is associated with various adverse health outcomes in children and adolescents, including low birth weight and impaired lung growth and function.

26 Aug 2012

Coronary artery calcium tool proves effective in detecting risk of cardiovascular disease

Heart calcium scans are far superior to other assessment tools in predicting the development of cardiovascular disease in individuals currently classified at intermediate risk by their doctors, according to researchers at Wake Forest Baptist Medical Center.

22 Aug 2012

HDL cholesterol benefits reduced with high C-reactive protein

The cardioprotective effects of high-density lipoprotein cholesterol are compromised in the presence of elevated high-sensitivity C-reactive protein, report researchers.

21 Aug 2012

Total cholesterol test can identify patients at increased risk of heart disease

Researchers in India have developed a total cholesterol test that uses a digital camera to take a snapshot of the back of the patient's hand rather than a blood sample. The image obtained is cropped and compared with images in a database for known cholesterol levels.

18 Aug 2012

Implanted cells' therapeutic properties depend on their shape

Tissue implants made of cells grown on a sponge-like scaffold have been shown in clinical trials to help heal arteries scarred by atherosclerosis and other vascular diseases. However, it has been unclear why some implants work better than others.

16 Aug 2012

U of U researchers receive NIH grant to study cellular and molecular causes of blood clots

University of Utah Department of Medicine researchers have received $16 million from the National Institutes of Health (NIH) to set up a translational research center to study the cellular and molecular causes of blood clots, a serious threat to millions of people who have diabetes, are obese or have other metabolic disorders.

15 Aug 2012

CD4 T cells orchestrate inflammatory attack on the artery wall

Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system.

15 Aug 2012

Cathepsins may attack one another instead of the bodily proteins

Researchers for the first time have shown that members of a family of enzymes known as cathepsins - which are implicated in many disease processes - may attack one another instead of the bodily proteins they normally degrade. Dubbed "cathepsin cannibalism," the phenomenon may help explain problems with drugs that have been developed to inhibit the effects of these powerful proteases.

15 Aug 2012

Insurance status affects survival after cardiac event

Patients admitted to hospital with an acute cardiac event have higher rates of mortality if they are underinsured compared with those who have private insurance, show US study results.

14 Aug 2012

New class of drugs may prove useful in treating cancer and aging-associated disorders

In a study published in the Proceedings of the National Academy of Sciences (PNAS) on Aug. 6, an international team led by Igor Roninson, of the University of South Carolina and the Medical University of South Carolina, reported the development of a new class of drugs that may prove useful in the treatment of cancer and aging-associated disorders.

14 Aug 2012

Eating egg yolks accelerates atherosclerosis in a manner similar to smoking

Newly published research led by Dr. David Spence of Western University, Canada, shows that eating egg yolks accelerates atherosclerosis in a manner similar to smoking cigarettes.

14 Aug 2012

Study examines trends in serum lipid concentrations among U.S. children and adolescents

In a study involving more than 16,000 U.S. children and adolescents, there has been a decrease in average total cholesterol levels over the past 2 decades, although almost 1 in 10 had elevated total cholesterol in 2007-2010, according to a study in the August 8 issue of JAMA.

8 Aug 2012

Underinsured CVD patients die sooner, irrespective of race

Insurance status is a better predictor of survival after a serious cardiac event than race, and may help explain racial disparities in health outcomes for cardiovascular disease. A new study by Derek Ng, from the Johns Hopkins Bloomberg School of Public Health in the US, and his team shows that race is not linked to an increased risk of death but being underinsured is a strong predictor of death among those admitted into hospital with a serious cardiac event.

7 Aug 2012

Exercise benefits influenced by sRAGE levels in diabetes

Increased levels of the soluble form of the receptor for advanced glycation end products may underly the beneficial effects of exercise in patients with Type 2 diabetes, research shows.

3 Aug 2012

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

'What defines obesity in children' is a very important question, primarily because we need to use one definition in order to be able to compare the prevalence of obesity in different countries. It is also important to have a single definition in order to evaluate whether interventions are successful or not.

31 Jul 2012

Working outside 9-5 shifts vascular risk

People who undertake shift work may be at a higher risk for vascular events than those who do not, researchers say in the BMJ.

31 Jul 2012

Anakinra can dramatically limit amount of brain damage in stroke patients

Scientists led by the President of The University of Manchester have demonstrated a drug which can dramatically limit the amount of brain damage in stroke patients.

From The University of Manchester 27 Jul 2012

Regeneron reports total revenues of $304 million for second quarter 2012

Regeneron Pharmaceuticals, Inc. announced financial and operating results for the second quarter of 2012 and provided an update on development programs.

25 Jul 2012

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

The elevated risk of cardiovascular disease seen in patients infected with HIV appears to be associated with increased inflammation within the arteries, according to a study that will appear in a special issue of JAMA published in conjunction with the International AIDS Conference.

23 Jul 2012

Only 63% of New Yorkers on Medicaid with chronic conditions are adherent to drug regimens

A new study published online this month in the Journal of Urban Health conducted by researchers in the Department of Population Health at NYU Langone Medical Center, the New York City Department of Health and Mental Hygiene, and the New York State Department of Health found only 63 percent of New Yorkers on Medicaid with chronic conditions including hypertension, diabetes and high cholesterol are adherent to medication regimens.

19 Jul 2012

Atherosclerosis News and Research

Further Reading

Study addresses important early risk factors of cardiovascular health in adolescents

Coronary artery calcium tool proves effective in detecting risk of cardiovascular disease

HDL cholesterol benefits reduced with high C-reactive protein

Total cholesterol test can identify patients at increased risk of heart disease

Implanted cells' therapeutic properties depend on their shape

U of U researchers receive NIH grant to study cellular and molecular causes of blood clots

CD4 T cells orchestrate inflammatory attack on the artery wall

Cathepsins may attack one another instead of the bodily proteins

Insurance status affects survival after cardiac event

New class of drugs may prove useful in treating cancer and aging-associated disorders

Eating egg yolks accelerates atherosclerosis in a manner similar to smoking

Study examines trends in serum lipid concentrations among U.S. children and adolescents

Underinsured CVD patients die sooner, irrespective of race

Exercise benefits influenced by sRAGE levels in diabetes

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

Working outside 9-5 shifts vascular risk

Anakinra can dramatically limit amount of brain damage in stroke patients

Regeneron reports total revenues of $304 million for second quarter 2012

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

Only 63% of New Yorkers on Medicaid with chronic conditions are adherent to drug regimens

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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