Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Study explores links between genetic susceptibility and heterogeneous phenotypes of lymphedema

Each year, about 1.38 million women worldwide are diagnosed with breast cancer. Advances in diagnosis and treatment have facilitated a 90-percent, five-year survival rate, among those treated.

9 Feb 2017

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

One of the most promising areas of cancer research is personalized therapy using precision medicine. The National Cancer Institute's NCI-MATCH is a large, ongoing clinical trial that matches tumors to therapies based on the tumor's genetic characteristics.

7 Feb 2017

Single Molecule Detection of Proteins in Single Cells

We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my laboratory at the time.

From Pittcon 3 Feb 2017

Precision-medicine approach could improve accuracy of PSA-based prostate cancer screening tests

A new study led by researchers at UC San Francisco and Kaiser Permanente has identified genetic predictors of normal prostate-specific antigen (PSA) levels in healthy men, which could be used to improve the accuracy of PSA-based prostate cancer screening tests.

3 Feb 2017

New PET radiotracer effectively detects early and advanced stages of prostate cancer

In the featured article from the February 2017 issue of the Journal of Nuclear Medicine, researchers document the first-in-human application of a new imaging agent to help find prostate cancer in both early and advanced stages and plan treatment.

1 Feb 2017

Sanford clinical study exploring immunotherapy drug to treat patients with advanced esophageal cancer

A clinical trial at Sanford Health is studying if an immunotherapy drug developed by Merck might be able to treat certain patients with advanced esophageal cancer. The Merck Keynote 181 trial is now open at Sanford.

31 Jan 2017

Tiny transport vesicles and shifts in metabolism can signal big changes in cancer tissues

Microscopic shifts in metabolism and increases in tiny transport vesicles out of tumor cells preface larger changes to the tumor environment and could prepare the way for cancerous cells to spread and metastasize, University of Illinois researchers report.

28 Jan 2017

GUMC researchers describe lab technique to fill gaps in clinical care and research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

28 Jan 2017

Pulmospheres could serve as personalized, predictive model for assessing effect of IPF drugs

Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from University of Alabama at Birmingham scientists presented today in JCI Insight, a journal of the American Society for Clinical Investigation.

27 Jan 2017

Lancet study: Advanced MRI doubles detection of aggressive tumours

A study published in The Lancet on 19th January 2017 entitled ‘Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study’ shows that using advanced MRI almost doubles the number of aggressive tumours detected.

27 Jan 2017

HCI scientists uncover new way that bones get destroyed through breast cancer

Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute at the University of Utah have identified a new way that bones get destroyed through cancer.

25 Jan 2017

Researchers develop new high-tech medical device to make brain surgery safer

A new high-tech medical device to make brain surgery safer has been developed by researchers at the University of Adelaide.

20 Jan 2017

A quarter of men could safely avoid prostate biopsy if MRI is used

Performing an MRI scan of men with suspected prostate cancer could spare a quarter of men from having to undergo prostate biopsy, according to a study published in The Lancet.

20 Jan 2017

Overall survival of advanced NSCLC patients receiving treatment better than untreated patients

Non-small cell lung cancer patients with advanced disease receiving standard of care treatment have a higher overall survival than similar patients not receiving treatment.

19 Jan 2017

UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages

Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer antibodies.

11 Jan 2017

Columbia University Medical Center to evaluate Biocept's Target Selector platform to diagnose LM in breast cancer patients

Biocept, Inc., a leading commercial provider of clinically actionable liquid biopsy tests designed to improve the outcomes of cancer patients, announces that Columbia University Medical Center will conduct a study to evaluate the clinical utility of the Company's Target Selector™ platform to diagnose leptomeningeal metastases (LM) in patients with breast cancer.

30 Dec 2016

New molecular imaging technologies can make it easier to treat cancers, minimize side effects

New molecular imaging technologies can make it easier to diagnose, monitor, and treat cancers while potentially saving patients from undergoing therapies that are likely to be ineffective and playing a role in minimizing side effects, according to experts from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania.

30 Dec 2016

Study reveals impact of histology on SBRT treatment in early-stage NSCLC patients

Early-stage non-small cell lung cancer (NSCLC) patients with squamous cell carcinoma (SqCC) have a significantly higher rate of local failure after stereotactic body radiation therapy (SBRT) than other NSCLC histological subtypes.

23 Dec 2016

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

New data presented at the 2016 San Antonio Breast Cancer Symposium (SABCS) demonstrate that analyzing tumor biology with the Oncotype DX test can identify patients unlikely to benefit from chemotherapy prior to breast cancer surgery (neoadjuvant setting) and guide treatment decisions without compromising outcomes.

22 Dec 2016

U-M researchers identify gene expression linked to gender differences in autoimmune diseases

Women represent nearly 8 out of every 10 people with autoimmune diseases. Although the statistics are well-known, the scientific community is still trying to figure out why women's immune systems are more likely to become overactive and attack their own healthy cells.

20 Dec 2016