Cancer Treatment News and Research

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Grouping tumors by 'immune archetypes' points the way to personalized immunotherapies

The UCSF researchers, led by first co-authors Alexis Combes, PhD, and Bushra Samad, MS, and senior author, Max Krummel, PhD, obtained tumor specimens from 78 UCSF clinicians, and surveyed 364 tumors biopsies from patients and categorized them into groups based on their immune microenvironment.

7 Jan 2022

Researchers study immune cell invasion process in living fruit fly embryos

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

6 Jan 2022

The war on cancer at 50: The origin story begins with a socialite citizen-lobbyist

The roots of the National Cancer Act can be traced to a small home in Watertown, Wisconsin. In the early 1900s, a girl named Mary tagged along when her mother went to visit their laundress, Mrs. Belter, who had breast cancer.

6 Jan 2022

New engineered nanomaterials help capture chemotherapy drugs to avoid tissue damage

Standard chemotherapies may efficiently kill cancer cells, but they also pose significant risks to healthy cells, resulting in secondary illness and a diminished quality of life for patients. To prevent the previously unavoidable damage, researchers, led by Penn State, have developed a new class of nanomaterials engineered to capture chemotherapy drugs before they interact with healthy tissue.

6 Jan 2022

Access to basic integrative healthcare services increases breast cancer patient's chance of survival

Breast cancer patients treated at hospitals and health systems that educate patients and provide integrative health services have a better chance of survival compared to those treated at institutions with few of these resources, according to a new study published in the Journal of Oncology.

29 Dec 2021

Researchers identify novel cancer markers in patients with aggressive prostate cancer

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome.

22 Dec 2021

Researchers identify new mechanism that impairs cancer cell proliferation and induces death

UAB and Vall d'Hebron researchers identified the mechanism by which inhibitors of the ERK5 protein kinase impair the proliferation of cancer cells and induce their death. The results, obtained using human cancer cell lines, demonstrate that ERK5 inhibition activates cytotoxic autophagy, a process that triggers cancer cell death, without affecting healthy cells. A combination of ERK5 inhibitors and chemotherapy could improve cancer treatment.

22 Dec 2021

Transcription factor Blimp1 identified as potential target for modulating T-reg activity to treat cancer

In cancer, a major obstacle to anti-tumor immunity and immunotherapy treatment is the infiltration of regulatory T cells, or T-reg cells, into a tumor. These immune cells generally turn down the immune response, and they can prevent the immune system from destroying cancer cells.

22 Dec 2021

Dreaded microbe can silence multiple types of pain, study suggests

Anthrax has a scary reputation. Widely known to cause serious lung infections in humans and unsightly, albeit painless, skin lesions in livestock and people, the anthrax bacterium has even been used as a weapon of terror.

20 Dec 2021

Succinate receptor can be a potential target for cancer treatment

Cancer cells show unchecked rapid growth beyond tissue boundaries that is no longer stopped by normal control mechanisms. Due to this rapid growth, the metabolism of cancer cells is altered compared to that of cells that grow normally.

18 Dec 2021

Combination treatment can effectively inhibit tumor growth

Researchers at the Paul Scherrer Institute PSI have tested various methods to check how effective they are in combatting certain types of cancer.

15 Dec 2021

Study provides new insights into molecular drivers of treatment resistance in prostate cancer

An international research team co-led by scientists at Roswell Park Comprehensive Cancer Center and The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified an important accelerator of treatment-resistant prostate cancer.

14 Dec 2021

Henry Ford surgeons use unique approach to perform first precision prostatectomy

Surgeons at Henry Ford Health System's Vattikuti Urology Institute performed what is believed to be the first precision prostatectomy through the bladder using a single port robotic surgical system.

13 Dec 2021

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

NCCN publishes new guidelines to help cervical cancer patients become more informed about care

The National Comprehensive Cancer Network has published new NCCN Guidelines for Patients: Cervical Cancer to help people with cervical cancer become more informed, suggest what conversations to have with their doctor, and be active decision makers in their treatment.

13 Dec 2021

Protein can protect the heart from damage following cancer treatment

Cancer treatment can be tough on the body, but for the patient to survive the cancer, it's often necessary to go through with the treatment anyway.

13 Dec 2021

WHO and St. Jude announce plans to improve children's access to cancer medicines

The World Health Organization and St. Jude Children's Research Hospital today announced plans to establish a platform that will dramatically increase access to childhood cancer medicines around the world.

13 Dec 2021

Former diabetes drug may help in the treatment of breast cancer, study shows

Findings from a new study led by Yale Cancer Center show the small molecule inhibitor drug, PF05175157, originally developed to treat diabetes by Pfizer, may help in the treatment of breast cancer.

12 Dec 2021

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Despite preliminary supporting evidence that the dopaminergic agent bupropion might improve sexual desire for female cancer survivors, the NRG Oncology CC004 clinical trial determined that bupropion did not improve outcomes when compared to a placebo.

10 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Cancer Treatment News and Research

Grouping tumors by 'immune archetypes' points the way to personalized immunotherapies

Researchers study immune cell invasion process in living fruit fly embryos

The war on cancer at 50: The origin story begins with a socialite citizen-lobbyist

New engineered nanomaterials help capture chemotherapy drugs to avoid tissue damage

Access to basic integrative healthcare services increases breast cancer patient's chance of survival

Researchers identify novel cancer markers in patients with aggressive prostate cancer

Researchers identify new mechanism that impairs cancer cell proliferation and induces death

Transcription factor Blimp1 identified as potential target for modulating T-reg activity to treat cancer

Dreaded microbe can silence multiple types of pain, study suggests

Succinate receptor can be a potential target for cancer treatment

Combination treatment can effectively inhibit tumor growth

Study provides new insights into molecular drivers of treatment resistance in prostate cancer

Henry Ford surgeons use unique approach to perform first precision prostatectomy

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

NCCN publishes new guidelines to help cervical cancer patients become more informed about care

Protein can protect the heart from damage following cancer treatment

WHO and St. Jude announce plans to improve children's access to cancer medicines

Former diabetes drug may help in the treatment of breast cancer, study shows

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

Your guide to microplate readers for cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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