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Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

If your DNA is a cookbook, a single gene is a recipe. But it's a flexible recipe that if edited one way can make a pie; edited another way can make a cake. And that difference can mean cancer, as a team of researchers who looked at those gene editors writes in the 26 November issue of Cell Reports.

26 Nov 2019

Validation of new method for studying how different drugs interact in the body

Scientists at Oregon State University may have proven how much people love coffee, tea, chocolate, soda and energy drinks as they validated their new method for studying how different drugs interact in the body.

26 Nov 2019

Study shows how fiber spacing could control cell sticking

Researchers from the Mechanobiology Institute at the National University of Singapore have shown that cells can attach to the fibrous protein meshwork that surrounds them only if the fibers are spaced close enough.

26 Nov 2019

New way to thwart HIV infection at early stages

1.7 million. That's how many people are infected with the human immunodeficiency virus (HIV) each year worldwide. 1.7 million people who are condemned to lifelong antiretroviral therapy (ART) or risk developing fatal AIDS . Out of the 37.9 million people living with HIV (PLWH), 22.3 million have access to ART, allowing them to have an almost normal lifespan.

26 Nov 2019

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows.

26 Nov 2019

New method to separate two variants of common herpes virus linked to multiple sclerosis

Researchers at Karolinska Institutet have developed a new method to separate between two different types of a common herpes virus that has been linked to multiple sclerosis.

26 Nov 2019

Study reports discovery of tendon stem cells

Being made up of flesh and bone, the human body often suffers injuries due to tendon damage caused by various acute or chronic events. As these damaged tissues recover, scar tissue builds up, causing a slow and often painful recovery.

25 Nov 2019

Exploring the link between macular degeneration and retinitis pigmentosa

Four words you never want to hear from the eye doctor are retinitis pigmentosa and macular degeneration.

25 Nov 2019

FDA-approved drug to prevent organ rejection may slow skin aging

The search for youthfulness typically turns to lotions, supplements, serums and diets, but there may soon be a new option joining the fray.

25 Nov 2019

Tips for staying healthy during the holiday season

The holiday season is a time with family, friends and fun, but it is also a time that is filled with lots of food and sweets.

25 Nov 2019

New antiviral drug drives treatment resistance in influenza viruses

On January 31, 2019, an 11-year old boy in Japan went to a medical clinic with a fever. The providers there diagnosed him with influenza, a strain called H3N2, and sent him home with a new medication called baloxavir.

25 Nov 2019

Scientists discover new approach to treating incurable leukemia in children

Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people.

25 Nov 2019

New electrochemical CRISPR biosensor can help improve diagnosis of diseases

The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors - which scientists can use to edit genetic material - in order to better diagnose diseases such as cancer.

25 Nov 2019

Research shows how cilia and exocyst contribute to extracellular vesicle production

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology.

25 Nov 2019

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

25 Nov 2019

Research yields potent antimicrobial that works against staph infection

Research led by scientists from McMaster University has yielded a potent antimicrobial that works against the toughest infectious disease strains. The find could be the beginning of developing new therapeutics to combat drug-resistant infections.

25 Nov 2019

New partnership aims to explore, cultivate innovations in cell and gene therapy

Some patients who have not responded to traditional medicines are now experiencing remarkable recoveries thanks to next-generation immunotherapies. These therapies equip a patient's own immune cells to recognize, target, and destroy cancer cells.

25 Nov 2019

New flu drug makes influenza viruses develop resistance

Researchers have discovered a mutation in strains of influenza treated with a drug that makes the virus resistant to treatment.

25 Nov 2019

Potent antimicrobial could combat antibiotic-resistant MRSA infections

Scientists have discovered a strong antimicrobial that is effective against some of the strongest infectious diseases.

25 Nov 2019

New targeted treatment to fight against deadly pancreatic cancer

Every day, more than 1200 people worldwide are told they have pancreatic cancer. Within 12 months, 80 per cent of them will have succumbed to the disease.

25 Nov 2019