Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

Calpain-mediated mGluR1-alpha truncation

Tricking a key enzyme can soothe over-excited receptors in the brain, say neuroscientists, calling this a possible strategy against stroke, Alzheimer's and other neurodegenerative diseases.

31 Jan 2007

FDA approves Neuren's phase 3 Glypromate trial

Neuren Pharmaceuticals has announced that the US Food and Drug Administration (FDA) has accepted its investigational new drug application (IND) and authorised the Company to proceed with its Phase 3 trial to prevent cognitive impairment following major cardiac surgery using Glypromate.

30 Jan 2007

Stroke risk for sickle cell children with early complications

Children with sickle cell disease who experienced major complications such as pain and lung disease early in life are at no greater risk for stroke or death during later childhood, new research from UT Southwestern Medical Center shows.

30 Jan 2007

Magnetic resonance angiography of supraaortic arteries

A novel type of contrast-enhanced magnetic resonance (MR) angiography is highly accurate in identifying blockages in the arteries that carry blood to the brain, according to a study in the February issue of Radiology.

30 Jan 2007

Startling results from first study of HIV dementia on the Africa

An international study led by Johns Hopkins suggests that the rate of HIV-associated dementia is so high in sub-Saharan Africa that HIV dementia along with Alzheimer's disease and dementia from strokes may be among the most common forms of dementia in the world.

30 Jan 2007

Stroke treatment helps victims recover brain function

A small but significant study in the U.S. has found that a treatment which was designed to clear blocked carotid arteries and prevent stroke has also improved brain function.

29 Jan 2007

Multiple sclerosis far more common than previously thought

A new review of hundreds of research articles has shown that the prevalence of multiple sclerosis (MS) is far higher than previously thought amongst the U.S. population.

29 Jan 2007

Gene produces springy protein keeping nerve cells flexible

If you bend a knee or an elbow, the nerves in your limbs stretch but do not break. A University of Utah study suggests why: A gene produces a springy protein that keeps nerve cells flexible. When the gene was disabled in tiny nematode worms, their nerve cells literally broke.

29 Jan 2007

Number of Parkinson's sufferers will double in next 25 years

The study highlights the significant challenge facing countries with rapidly growing economies, particularly in Asia, many of which are ill prepared to meet this impending public health threat.

29 Jan 2007

North American Menopause Society releases guidelines saying HRT beneficial for younger women

The North American Menopause Society on Thursday released a revised position statement that said the benefits of short-term hormone replacement therapy for treatment of menopausal women likely outweigh the risks for younger women, the Wall Street Journal reports.

28 Jan 2007

Linemen more than twice as likely as other players to have metabolic syndrome

After retirement, National Football League (NFL) linemen - generally the heaviest players - are more than twice as likely as other players to have a syndrome that puts them at risk for heart disease, stroke and other cardiovascular diseases

28 Jan 2007

Magnetic resonance imaging better than computed tomography for the detection of acute stroke

Magnetic resonance imaging (MRI) is better than the more commonly used computed tomography (CT) for the detection of acute stroke, according to an Article in this week's issue of The Lancet.

28 Jan 2007

New prognostic instrument improves prediction of stroke risk after TIA

The existing prognostic scores for early-risk stroke prediction after transient ischaemic attack (TIA have been validated and refined to develop a unified score that is more predictive than previous methods, according to an Article published in this week's issue of The Lancet.

28 Jan 2007

Alteplase for appropriate stroke patients is safe and effective

The thrombolytic drug alteplase, despite recent concerns, is safe and effective in routine clinical use when used within 3 hours of stroke onset, according to an observational study published in this week's issue of The Lancet.

28 Jan 2007

Patients with acute stroke who receive stroke-unit care less likely to die

Patients with acute stroke who receive stroke-unit care are less likely to die or become disabled than patients treated in a conventional hospital ward, according to an observational follow-up study published in this week's issue of The Lancet.

28 Jan 2007

Manipulation of proliferation and differentiation of human bone marrow derived neural stem cells in vitro and in vivo

Stem cells taken from adult human bone marrow have been manipulated by scientists at the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai Medical Center to generate aggregates of cells called spheres that are similar to those derived from neural stem cells of the brain.

28 Jan 2007

Neuren reports successful NNZ-2566 safety trial results

Neuren Pharmaceuticals Ltd has successfully completed a Phase 1 safety and tolerability trial of its second lead candidate, NNZ-2566, which is being developed to treat traumatic brain injury (TBI).

16 Jan 2007

Fibrinogen molecule structure acts as a molecular spring

Researchers at the University of Pennsylvania School of Medicine and the School of Arts and Sciences have shown that a well-known protein structure acts as a molecular spring, explaining one way that clots may stretch and bend under such physical stresses as blood flow.

14 Jan 2007

Stem cell research discovery could mean 'big things' for cancer

A new discovery in stem cell research may mean big things for cancer patients in the future. Gary Van Zant, Ph.D., and a research team at the University of Kentucky published their findings in Nature Genetics.

14 Jan 2007

Hospital death rate study reveals wide variations and stresses importance of Registered Nurses

Hospital death rates can be reduced by employing more Registered Nurses and the routine use of care maps or protocols, according to a study in the latest UK-based Journal of Advanced Nursing.

14 Jan 2007