Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself.

26 May 2023

Tracking changes in blood vessels may hold clues to early detection of neurodegenerative diseases

While age-related brain disorders like Alzheimer's disease often develop slowly across an individual's lifetime, they usually aren't detected until symptoms have already started.

26 May 2023

$4.5 million grant to fund research exploring link between exercise and slowing Alzheimer's progression

A $4.5 million groundbreaking grant will fund research to explore a promising link between aerobic exercise and slowing the progression of Alzheimer's disease in a study led by an Arizona State University researcher.

26 May 2023

Insights into the direction and extent of gut microbiome dysbiosis in Alzheimer’s disease and mild cognitive impairment

Researchers performed a meta-analysis to determine the association between intestinal microbiota and Alzheimer’s disease (AD).

26 May 2023

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

In a noteworthy case study published in the Journal of Alzheimer's Disease investigators report autopsy findings in a 65-year-old woman with Alzheimer's disease (AD) who received three open label infusions of the experimental anti-amyloid beta (Aβ) antibody drug lecanemab.

25 May 2023

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

A possible explanation has been found in a study for why apoE4, the most significant genetic risk factor associated with Alzheimer's disease, fails to protect the brain from inflammation.

25 May 2023

Superior cognition in individuals who are 90+ associated with resilience to neurodegenerative pathologies

A University of California, Irvine-led team of researchers have discovered that the oldest-old, those who live to be 90+ and have superior cognitive skills, have similar levels of brain pathology as Alzheimer's patients, however, they also have less brain pathology of other neurodegenerative diseases that cause memory and thinking problems.

25 May 2023

People with Alzheimer's disease more likely to develop epilepsy and vice versa

People with a genetic predisposition for Alzheimer's disease may have an increased risk of epilepsy and people with a certain type of epilepsy may have an increased risk of developing Alzheimer's disease, according to a study published in the May 24, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

25 May 2023

Chocoholics rejoice: Regular chocolate consumption linked to slightly lower risk of mortality in women

Researchers examine the relationship between chocolate consumption and mortality in women.

23 May 2023

Metabolic sensors may play a role in the development of Alzheimer's disease, study suggests

It's well-known that people with Type 2 diabetes are at an increased risk of developing Alzheimer's disease, but the reason why isn't fully understood and is an area of current research.

22 May 2023

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

research paper presents a perspective on tackling the healthcare challenge of Alzheimer's disease (AD) by shifting focus to pre-dementia stages and advocating for personalized medicine through improved diagnosis, prediction, and prevention strategies, empowering patients to actively manage their health and delay the onset of dementia.

22 May 2023

Gout unveiled as surprising culprit in neurodegenerative diseases

Research highlights the association between gout and neurodegenerative diseases, revealing that gout patients exhibit smaller brain volumes, increased brain iron markers, and a higher incidence of conditions such as dementia, Parkinson's disease, and essential tremor, particularly within the first three years after diagnosis.

22 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

Blood vessel abnormalities in the eye could drive Alzheimer's disease

Blood vessel abnormalities in the eye are a major factor in the progression of Alzheimer's disease, according to research from Cedars-Sinai investigators published in the peer-reviewed journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

22 May 2023

Researchers discover sex-specific genes, molecular pathways that contribute to Alzheimer's disease progression

Alzheimer's Disease (AD) is a complex neurodegenerative illness with genetic and environmental origins.

19 May 2023

BCG vaccine associated with reduced risk of Alzheimer's disease and related dementias

The Bacillus Calmette-Guérin (BCG) vaccine - which prevents tuberculosis - offers multiple beneficial effects, and it's currently a recommended therapy for non–muscle-invasive bladder cancer.

19 May 2023

What are the genetic associations between modifiable risk factors and Alzheimer's disease?

Researchers assessed associations between genetic risk factors and Alzheimer's.

19 May 2023

Turn down the heat: Spicy foods linked to memory decline in inactive seniors

Research investigates the association between spicy food consumption and Alzheimer's disease (AD) or cognitive decline in older adults. The study found that a high level of spiciness in food is associated with decreased memory or global cognition, and this relationship is worsened by a physically inactive lifestyle.

18 May 2023

Gamma frequency tactile stimulation can reduce Alzheimer's disease pathology and symptoms

Evidence that non-invasive sensory stimulation of 40 Hz gamma frequency brain rhythms can reduce Alzheimer's disease pathology and symptoms, already shown with light and sound by multiple research groups in mice and humans, now extends to tactile stimulation.

18 May 2023

Regular exercise may decrease the risk of developing Parkinson's disease

Getting regular exercise such as cycling, walking, gardening, cleaning and participating in sports may decrease the risk of developing Parkinson's disease, according to new research published in the May 17, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

18 May 2023

Alzheimer's Disease News and Research

Further Reading

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

Tracking changes in blood vessels may hold clues to early detection of neurodegenerative diseases

$4.5 million grant to fund research exploring link between exercise and slowing Alzheimer's progression

Insights into the direction and extent of gut microbiome dysbiosis in Alzheimer’s disease and mild cognitive impairment

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

Superior cognition in individuals who are 90+ associated with resilience to neurodegenerative pathologies

People with Alzheimer's disease more likely to develop epilepsy and vice versa

Chocoholics rejoice: Regular chocolate consumption linked to slightly lower risk of mortality in women

Metabolic sensors may play a role in the development of Alzheimer's disease, study suggests

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

Gout unveiled as surprising culprit in neurodegenerative diseases

Newly discovered molecule effectively destroys senescent cells

Blood vessel abnormalities in the eye could drive Alzheimer's disease

Researchers discover sex-specific genes, molecular pathways that contribute to Alzheimer's disease progression

BCG vaccine associated with reduced risk of Alzheimer's disease and related dementias

What are the genetic associations between modifiable risk factors and Alzheimer's disease?

Turn down the heat: Spicy foods linked to memory decline in inactive seniors

Gamma frequency tactile stimulation can reduce Alzheimer's disease pathology and symptoms

Regular exercise may decrease the risk of developing Parkinson's disease

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