Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Breakthrough in cancer research can help reduce heart failure, increase survival rates

A breakthrough by scientists at Queen's University Belfast could help reduce heart failure in cancer patients around the world, and ultimately increase survival rates.

10 Feb 2011

PBNC technology may help detect cardiac disease, reduce diagnostic costs

Heart disease is a silent killer, but new microchip technology from Rice University is expected to advance the art of diagnosis.

9 Feb 2011

New facilities for developing imaging tests in PESA CNIC-Santander study inaugurated

Felipe P-triz, Secretary of State for Research and Emilio Bot-n, president of Banco Santander have inaugurated today in Banco Santander Finantial City (located in Boadilla del Monte) the new facilities for developing the first imaging tests included in PESA (Progression of Early Subclinical Atherosclerosis) CNIC-Santander study.

8 Feb 2011

Cholesterol efflux capacity may protect against heart disease: Study

The discovery that high levels of high-density lipoprotein cholesterol are associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

4 Feb 2011

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

People who follow a vegan lifestyle - strict vegetarians who try to eat no meat or animal products of any kind - may increase their risk of developing blood clots and atherosclerosis or "hardening of the arteries," which are conditions that can lead to heart attacks and stroke. That's the conclusion of a review of dozens of articles published on the biochemistry of vegetarianism during the past 30 years.

3 Feb 2011

Positive results from Factor IX-CTP comparative study in hemophilic mice

PROLOR Biotech, today reported positive results from a comparative study of its biobetter longer-acting version of the hemophilia drug Factor IX in Factor IX-depleted hemophilic mice.

3 Feb 2011

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

Widespread screening or routine ultrasound for blocked neck arteries to determine stroke risk isn't necessary, according to new guidelines from the American Heart Association/American Stroke Association, American College of Cardiology and other groups.

1 Feb 2011

Single DNA variation linked to decreased risk of coronary disease in African-Americans

A team of scientists at Johns Hopkins and elsewhere has discovered that a single alteration in the genetic code of about a fourth of African-Americans helps protect them from coronary artery disease, the leading cause of death in Americans of all races.

28 Jan 2011

Study aims to determine risk of dementia, cognitive decline in middle-aged people

University of North Carolina at Chapel Hill researchers are co-leading a national study to examine whether middle-aged people's physical health influences their risk of dementia later in life.

28 Jan 2011

Cardiac stem cell therapy can rebuild damaged heart in children

Visionaries in the field of cardiac therapeutics have long looked to the future when a damaged heart could be rebuilt or repaired by using one's own heart cells. A study published in the February issue of Circulation, a scientific journal of the American Heart Association, shows that heart stem cells from children with congenital heart disease were able to rebuild the damaged heart in the laboratory.

27 Jan 2011

Interferon-alpha associated with increased risk of atherosclerosis in patients with SLE

Researchers in China have demonstrated interferon-alpha (IFN-α) is associated with increased risk of atherosclerosis in patients with systemic lupus erythematosus (SLE). For the first time, IFN-α priming was shown to promote lipid uptake and foam cell formation—a crucial step in plaque build-up. This activation of the IFN signaling pathway may be linked to the premature atherosclerosis risk in SLE.

27 Jan 2011

Scientists to develop enzyme that protects against nerve agents

Protection against nerve gas attack is a significant component of the defense system of many countries around the world. Nerve gases are used by armies and terrorist organizations, and constitute a threat to both the military and civilian populations, but existing drug solutions against them have limited efficiency.

25 Jan 2011

Human model of rare genetic disease reveals new clues to aging process

Scientists from A*STAR's Institute of Medical Biology (IMB) in Singapore and the University of Hong Kong's Department of Medicine have produced the world's first human cell model of progeria, a disease resulting in severe premature ageing in one in four to eight million children worldwide. This model has allowed them to make new discoveries concerning the mechanism by which progeria works.

25 Jan 2011

KineMed's fibrosis research program featured in Nature Medicine

KineMed Inc.'s fibrosis research program, which aims to advance the discovery and development of drugs to treat this major disease, is featured in the January edition of Nature Medicine.

24 Jan 2011

Positive interim data from ongoing V5 Phase IIb imm01 trial against tuberculosis

Immune Network, a company in the business of development and commercialization of immune therapies, announced today that its newly acquired business, Immunitor, has published interim data from the ongoing Phase IIb imm01 clinical trial of V5 in tuberculosis conducted at its second site in Ukraine.

24 Jan 2011

Functional tests are necessary to understand human disease despite genetic sequencing

Despite what you might have heard, genetic sequencing alone is not enough to understand human disease. Researchers at Duke University Medical Center have shown that functional tests are absolutely necessary to understand the biological relevance of the results of sequencing studies as they relate to disease, using a suite of diseases known as the ciliopathies which can cause patients to have many different traits.

24 Jan 2011

Stusy: HEPA filters may help reduce pollution-related cardiovascular health risks

Using inexpensive air filters may help reduce cardiovascular disease risk that results from exposure to air pollution, according to researchers from Canada, who studied healthy adultsliving in a small community in British Columbia where wood burning stoves are the main sources of pollution.

24 Jan 2011

Routine mammograms can show arterial calcium deposits in women with ESRD, CKD

Routine mammograms performed for breast cancer screening could serve another purpose as well: detecting calcifications in the blood vessels of patients with advanced kidney disease, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

21 Jan 2011

PROSPECT trial results shed new light on plaque types that cause unexpected heart attacks

Results from the PROSPECT clinical trial shed new light on the types of vulnerable plaque that are most likely to cause sudden, unexpected adverse cardiac events, and on the ability to identify them through imaging techniques before they occur.

21 Jan 2011

BUSM receives NIH grant to explore how chronic inflammation can lead to systemic diseases

A team of researchers at Boston University School of Medicine have been awarded a five-year, $7.7 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Diseases to explore how chronic inflammation can lead to systemic diseases.

20 Jan 2011

Atherosclerosis News and Research

Further Reading

Breakthrough in cancer research can help reduce heart failure, increase survival rates

PBNC technology may help detect cardiac disease, reduce diagnostic costs

New facilities for developing imaging tests in PESA CNIC-Santander study inaugurated

Cholesterol efflux capacity may protect against heart disease: Study

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

Positive results from Factor IX-CTP comparative study in hemophilic mice

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

Single DNA variation linked to decreased risk of coronary disease in African-Americans

Study aims to determine risk of dementia, cognitive decline in middle-aged people

Cardiac stem cell therapy can rebuild damaged heart in children

Interferon-alpha associated with increased risk of atherosclerosis in patients with SLE

Scientists to develop enzyme that protects against nerve agents

Human model of rare genetic disease reveals new clues to aging process

KineMed's fibrosis research program featured in Nature Medicine

Positive interim data from ongoing V5 Phase IIb imm01 trial against tuberculosis

Functional tests are necessary to understand human disease despite genetic sequencing

Stusy: HEPA filters may help reduce pollution-related cardiovascular health risks

Routine mammograms can show arterial calcium deposits in women with ESRD, CKD

PROSPECT trial results shed new light on plaque types that cause unexpected heart attacks

BUSM receives NIH grant to explore how chronic inflammation can lead to systemic diseases

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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