Central Nervous System News and Research

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Breakthrough in the treatment of Restless Legs Syndrome

New research published in The Journal of Physiology presents a breakthrough in the treatment of Restless Legs Syndrome.

13 Nov 2018

Study provides new clues to origin and development of multiple sclerosis

Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis, shows that they might have a significant role in the development of the disease.

12 Nov 2018

Gladstone scientists gain new insights into the aging brain

The protein klotho has been shown to promote longevity and counteract aging-related impairments. Having more klotho seems to allow for longer and healthier lives, whereas a depletion of this molecule accelerates aging and may contribute to age-related diseases.

12 Nov 2018

B cell accumulation triggers nervous system damage in MS

B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease Multiple Sclerosis (MS) they can damage nerve tissue.

8 Nov 2018

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease, the accumulation of fat in the liver of people who drink little or no alcohol, affects 1 in 3 Americans. NAFLD is a significant risk factor for Type 2 diabetes, insulin resistance, and hepatic carcinoma, and incidence of the disease is increasing with the growing obesity epidemic in the United States.

8 Nov 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

Scientists create tiny, biodegradable scaffold to transplant stem cells and deliver drugs

Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer's and Parkinson's diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries.

5 Nov 2018

Ischemia-induced stem cells can be promising candidates for CNS injury therapeutics

Researchers have performed a careful comparison between locally generated, ischemia-induced, multipotent stem cells and bone marrow-derived mesenchymal stem cells in an effort to determine which cell type has greater central nervous system repair capacity.

26 Oct 2018

New discovery may unlock development of next-generation sleeping pill

Insomnia is one of the major sleep problems with an estimated prevalence of 10% to 15% in the general population and 30% to 60% in the older population. Moreover, insomnia frequently co-occurs with a wide range of psychiatric disorders, including depression and anorexia.

26 Oct 2018

Kent State professor receives NIH grant to study neurological roots of fear memories

People who suffer trauma will, with few exceptions, never forget what happened to them, but a Kent State University researcher may be able to offer them the hope of living without constant fear and anxiety.

25 Oct 2018

Identifying ways to improve existing guidelines for ethical human-animal chimera research

In Greek mythology, a chimera is a figure with the head of a lion, the body of a goat, and the tail of a serpent. But the concept is not entirely imaginary.

25 Oct 2018

Scientists engineer antiviral peptide that exploits Achilles' heel of Zika virus

Scientists at Nanyang Technological University, Singapore have engineered an antiviral peptide that exploits the Zika virus at its Achilles' heel - the viral membrane - hence stopping the virus from causing severe infections.

24 Oct 2018

Tall people more likely to get cancers, finds study

A new study suggests that tall people are more likely to get cancers because they have more number of cells that can undergo dangerous mutations.

24 Oct 2018

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

With a pair of RO1 grants from the National Institutes of Health, pain researcher Daniela Salvemini, Ph.D., will embark on two new research projects, studying chemotherapy-induced cognitive impairment, or "chemo brain," symptoms and unwanted side effects of opioids.

23 Oct 2018

Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC

Takeda Pharmaceutical Company Limited today announced that intracranial efficacy data from the Phase 3 ALTA-1L (ALK in Lung Cancer Trial of BrigAtinib in 1st Line) trial showed improved intracranial progression-free survival (PFS) and intracranial objective response rate (ORR) with ALUNBRIG (brigatinib) compared to crizotinib among anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC) patients.

22 Oct 2018

Green filters increase reading speed for children with dyslexia

Reading, one of the most difficult activities for children with dyslexia, can be improved by the use of green filters.

19 Oct 2018

URMC researchers discover new approach to deliver therapeutics to the brain

Researchers at the University of Rochester Medical Center have discovered a potentially new approach to deliver therapeutics more effectively to the brain. The research could have implications for the treatment of a wide range of diseases, including Alzheimer's, Parkinson's, ALS, and brain cancer.