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Researchers solve 3D structure of supramolecular protein nanoparticle using cryo-electron microscopy

Nanoparticles and nanocages are attractive materials that may be applied in color agents, catalysts, and drug delivery. For real-world use, it is necessary to produce a large number of nanoparticles of uniform size and shape, but thus far, nanoparticle formation methods using metals have been widely researched, and the formation of nanoparticles with a certain shape and size have been realized.

6 Oct 2021

Cysteamine inhibits SARS-CoV-2 variants of concern in vitro

Researchers in the United States have shown that a compound currently used to treat cystinosis exhibits broad antiviral activity against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

5 Oct 2021

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests.

5 Oct 2021

Housing environment influenced mental health during COVID-19 pandemic

The last year and a half have been a struggle for all of us, and that's putting it lightly. But in terms of mental health, apartment-dwelling Americans - especially those living alone - may have suffered more mental health problems during the COVID-19 pandemic than those living with their families in the suburbs, suggests new research from the University of Georgia.

4 Oct 2021

Researchers publish new datasets to better train machine learning models for drug discovery

Polymorphs are molecules that have different molecular packing arrangements despite identical chemical compositions.

2 Oct 2021

Researchers use unnatural amino acids to create fluorescent proteins for studying biological systems

Proteins are the molecular machines that make all living things hum. They stop deadly infections, heal cells, capture energy from the sun and so much more.

2 Oct 2021

Scientists use new technique to study the effects of reactive electrophilic drugs

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple sclerosis, inflammation damages the protective myelin insulation around nerves, and the nerves themselves.

30 Sep 2021

Research examines the effectiveness of various oral hygiene tools

Do probiotics prevent gum disease? Is flossing necessary? Many patients are unable to confidently answer these questions and more due to the abundance of conflicting medical information

30 Sep 2021

The applications of nanomaterials against viral disease

The application of nanomaterials in the diagnosis, prevention, and treatment of viral diseases is reviewed in detail, highlighting areas of significant progress or stagnation from the past few decades.

30 Sep 2021

New SBIR award helps Temple scientists to explore the therapeutic potential of novel cannabis analog

More than 20 percent of adults in the United States live with chronic pain. For many affected individuals, long-term physical discomfort negatively impacts overall well-being, leading to reduced work output and increased anxiety and depression.

29 Sep 2021

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

Mark Bear, Picower Professor of Neuroscience at MIT, recalls the "eureka moment" 20 years ago when he realized that a severe developmental brain disorder - fragile X syndrome - might be treated with drugs that inhibit a neurotransmitter receptor called mGluR5.

29 Sep 2021

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

A new type of targeting chaperon protein HSP70 inhibitor QL47 was recently discovered by a team led by Prof. LIU Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences to treat FLT3-ITD-positive acute myeloid leukemia (AML).

27 Sep 2021

SARS-CoV-2 entry inhibitors show antiviral activity

A new study used a combination of a computer-aided drug design approach and cell-based in vitro assays to identify five potential SARS-CoV-2 inhibitors.

27 Sep 2021

Discovery points toward a new strategy for treating Parkinson's disease

University of Utah Health scientists have identified a molecule that slows cells' production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson's disease.

23 Sep 2021

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant's intestinal lining and causes death in up to a third of the cases.

23 Sep 2021

Unregulated polycyclic aromatic hydrocarbons contribute to global cancer risk

Whenever an organic matter is burned, such as in a wildfire, a power plant, a car's exhaust, or in daily cooking, the combustion releases polycyclic aromatic hydrocarbons (PAHs) - a class of pollutants that is known to cause lung cancer.

23 Sep 2021

In-mouth production of volatile sulfur compounds causes children to dislike Brassica vegetables

Many children, as well as adults, dislike Brassica vegetables, such as broccoli, cauliflower, cabbage and Brussels sprouts.

22 Sep 2021

Addressing Honey Fraud in Global Food Chains

In this interview, Peter Awram is an expert from the Worker Bee Honey Company, the largest apiary in British Columbia, Canada, and Gillian Wade, an expert in consumer class action litigation, discuss the issues facing honey producers.

From Bruker BioSpin Division 22 Sep 2021

Preventing Wine Adulteration

Gordon Burns is the technical director and co-founder of ETS Laboratories, which runs specialist wine analysis labs based in the Napa Valley in California. The North American wine industry has quite a different story to tell than honey that was discussed in another interview when it comes to authenticity issues.

From Bruker BioSpin Division 22 Sep 2021

Compound extracted from orchid could be a potential treatment option for prostate cancer

Research led by the Centenary Institute has found that a compound extracted from a commonly cultivated orchid could be a potential new treatment option for prostate cancer.

22 Sep 2021

Compound News and Research

Researchers solve 3D structure of supramolecular protein nanoparticle using cryo-electron microscopy

Cysteamine inhibits SARS-CoV-2 variants of concern in vitro

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Housing environment influenced mental health during COVID-19 pandemic

Researchers publish new datasets to better train machine learning models for drug discovery

Researchers use unnatural amino acids to create fluorescent proteins for studying biological systems

Scientists use new technique to study the effects of reactive electrophilic drugs

Research examines the effectiveness of various oral hygiene tools

The applications of nanomaterials against viral disease

New SBIR award helps Temple scientists to explore the therapeutic potential of novel cannabis analog

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

SARS-CoV-2 entry inhibitors show antiviral activity

Discovery points toward a new strategy for treating Parkinson's disease

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

Unregulated polycyclic aromatic hydrocarbons contribute to global cancer risk

In-mouth production of volatile sulfur compounds causes children to dislike Brassica vegetables

Addressing Honey Fraud in Global Food Chains

Preventing Wine Adulteration

Compound extracted from orchid could be a potential treatment option for prostate cancer

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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