Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Brain development in autistic Individuals differs from people with typical neurodevelopment, study confirms

A new study led by UC Davis MIND Institute researchers confirms that brain development in people with autism differs from those with typical neurodevelopment.

3 Mar 2023

Maternal obesity associated with adverse metabolic health outcomes in childhood

Research by the University of the Basque Country indicates that changes caused by maternal obesity could lead to adverse health outcomes in childhood.

3 Mar 2023

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

Epigenetic changes in the regulation of key stress gene detected in kids with abusive injuries

Epigenetic changes in the regulation of a key gene in the body's stress response system were detected in babies and young children with abusive injuries, as opposed to accidental, according to a pilot study published in the journal Pediatric Research.

2 Mar 2023

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

The study findings demonstrate the power of spatial single-cell transcriptomics in studying COVID-19 lung pathology and other health and disease conditions.

1 Mar 2023

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

In a recent study posted to the bioRxiv* pre-print server, researchers tested three next-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) inhibitors, namely, nirmatrelvir, ensitrelvir, and FB2001, using a novel cell-based assay.

1 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

Key 'traffic light' mechanism controlling genetic activity within cells revealed

A major new study in the journal Nature reveals a 'traffic light' mechanism controlling genetic activity within cells – a system which could potentially be targeted by cancer drugs already in development.

1 Mar 2023

An overview of the anti-inflammatory effects of nuts

Researchers summarize existing literature on the effects of consuming nuts on biomarkers of inflammation and oxidative stress.

28 Feb 2023

Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Researchers assessed T-cell tolerance checkpoints observed in atherosclerosis.

27 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

Study links obesity with 21 Alzheimer's disease-related genes

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Gene Expression News and Research

Further Reading

Brain development in autistic Individuals differs from people with typical neurodevelopment, study confirms

Maternal obesity associated with adverse metabolic health outcomes in childhood

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Epigenetic changes in the regulation of key stress gene detected in kids with abusive injuries

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

Key 'traffic light' mechanism controlling genetic activity within cells revealed

An overview of the anti-inflammatory effects of nuts

Researchers explore potential new target for cancer immunotherapy

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

Apolipoprotein E4 promotes the development of Alzheimer’s disease

NQO2 gene as a novel potential target in Parkinson’s disease

Study links obesity with 21 Alzheimer's disease-related genes

Dietary polyphenols may play a role in regulating inflammatory immune responses

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

Step-by-step process of rewiring cells to generate germ cell precursors

First fully human ovarian organoids provide insights about female reproductive health and disease

HKU research advances understanding of the fundamental biological processes of gene regulation

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