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Agreement to explore Optimer vehicles for targeted delivery of siRNA

New collaboration will evaluate Aptamer’s fibrotic liver delivery vehicles with siRNA.

From Aptamer Group 9 Jul 2024

GLP-1 drugs found to lower cancer risk in diabetes patients

Research finds that GLP-1 receptor agonists significantly reduce the risk of 10 out of 13 obesity-associated cancers in type 2 diabetes patients compared to insulins, but show varied results against metformin.

8 Jul 2024

UQ researchers unlock crucial molecular secrets of aging in cells

University of Queensland researchers have unlocked crucial molecular secrets of aging in cells, potentially paving the way to improve quality of life as people age.

8 Jul 2024

England sees shifting mortality trends with obesity: Cardiovascular deaths decline, neurological and respiratory deaths rise

Obesity-related mortality rates in England show complex trends between 2004 and 2019. While overall mortality rates among obese individuals declined, the study highlights shifting causes of death, including an increase in neurological and respiratory deaths.

7 Jul 2024

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, has successfully delivered the second preclinical candidate compound (PCC) in its collaboration with Fosun Pharma in June 2024, a potential innovative therapeutic using synthetic lethal strategy for the treatment of solid tumors.

5 Jul 2024

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

3 Jul 2024

Inflammation in early adulthood may be linked to memory and thinking problems at middle age

Having higher levels of inflammation in your 20s and 30s may be linked to having memory and thinking problems at middle age, according to a study published in the July 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

3 Jul 2024

Tampons can be potential source of toxic metals, study finds

Tampons from several brands that potentially millions of people use each month can contain toxic metals like lead, arsenic, and cadmium, a new study led by a UC Berkeley researcher has found.

3 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

Decoding the significance of subnormal liver enzyme activity

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

3 Jul 2024

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading.

2 Jul 2024

Advancements in immunotherapy for hepatocellular carcinoma offer hope to patients

Hepatocellular carcinoma (HCC) is a primary liver cancer predominantly arising from chronic liver diseases such as hepatitis B and C infections, alcohol abuse, and metabolic disorders.

2 Jul 2024

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

Regular booster doses of bivalent mRNA COVID-19 vaccines help neutralize multiple strains

People who have received solid organ transplants and take immunosuppressant medications to prevent rejection are among those most susceptible to the damaging effects of COVID-19, including breakthrough infections, severe illness, hospitalization and death.

2 Jul 2024

Bird flu virus detected in Alaskan polar bear

Researchers reported a natural infection of a highly pathogenic avian influenza A(H5N1) virus in a free-ranging juvenile polar bear in Alaska, highlighting the importance of wildlife health surveillance in detecting emerging pathogens.

2 Jul 2024

No organ is an island: Genetic study shows unique but interconnected aging markers

Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.

2 Jul 2024

Liver News and Research

Agreement to explore Optimer vehicles for targeted delivery of siRNA

GLP-1 drugs found to lower cancer risk in diabetes patients

UQ researchers unlock crucial molecular secrets of aging in cells

England sees shifting mortality trends with obesity: Cardiovascular deaths decline, neurological and respiratory deaths rise

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

Inflammation in early adulthood may be linked to memory and thinking problems at middle age

Tampons can be potential source of toxic metals, study finds

White blood cell type identified as important contributor to inflammation in obesity

Decoding the significance of subnormal liver enzyme activity

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

Advancements in immunotherapy for hepatocellular carcinoma offer hope to patients

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Regular booster doses of bivalent mRNA COVID-19 vaccines help neutralize multiple strains

Bird flu virus detected in Alaskan polar bear

No organ is an island: Genetic study shows unique but interconnected aging markers

Study shows the potential of heat treatments to promote healthier aging

KRISS develops world's first reference material for accurate body fat measurement in medical imaging

Asia Pacific faces hepatitis crisis: Urgent action needed to meet WHO targets

Regulatory T cells exist as large, mobile population that travels through body to repair damaged tissue

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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