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Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

A recent study assessed neutrophil extracellular trap formation and antiviral host response in high-risk COVID-19 patients.

8 Mar 2022

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A recent study predicted the efficacy of the SOBERANA 02 and SOBERANA Plus COVID-19 vaccines in children.

8 Mar 2022

Current and future perspectives of mRNA technology

New research reports on the current and future perspectives on messenger ribonucleic acid technology, the platform on which the first successful COVID-19 vaccine was based.

8 Mar 2022

Study finds Omicron BA.2 responsible for more but less infectious breakthrough infections

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) infections between December 23, 2021, and February 20, 2022, in Qatar to understand how Omicron subvariants, vaccination, and prior infection status impacted these cases.

8 Mar 2022

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

In a recent study posted to the medRxiv* preprint server, researchers investigated the efficacy of diagnostic tests for identifying severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants of concern (VOCs).

8 Mar 2022

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

In a recent study posted to the medRxiv*preprint server, a team of researchers from Israel developed and validated novel reverse transcriptase - quantitative polymerase chain reaction (RT-qPCR) assays. The new assays enable the rapid and high throughput identification and differentiation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 variants.

8 Mar 2022

Higher SARS-CoV-2 load in morning-collected samples

In a recent study posted to the medRxiv* preprint server, researchers identified that morning-collected nasal and saliva samples yielded better detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially in tests with low to moderate analytical sensitivity.

8 Mar 2022

Bacterial coinfection pervasiveness and antibiotic use in COVID-19 patients

In a recent study posted to the medRxiv* pre-print server, researchers conducted a meta-analysis to determine the bacterial coinfection and antibiotic usage prevalence in coronavirus disease 2019 (COVID-19) patients.

7 Mar 2022

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Researchers from Columbia Engineering, Fiocruz's Center for Technological Development in Health and the Oswaldo Cruz Institute in Brazil, Memorial Sloan Kettering Cancer Center, and Rockefeller University recently reported that, by combining inhibitors of polymerases and exonucleases--enzymes that allow SARS-CoV-2 to reproduce--they were able to reduce SARS-CoV-2 replication 10 times more than when using just the polymerase inhibitors.

7 Mar 2022

Delta and Omicron coinfections identified in France

A new study shows both the Omicron and Delta variants were able to infect patients with healthy immune function.

7 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

Study explores differentially expressed immune genes for COVID-19 patient stratification

In a new study, researchers determined the transcriptional signatures associated with the severity of COVID-19.

7 Mar 2022

Exploring biomedical literature and clinical trial records to identify new drug combinations for COVID-19 treatment

Researchers extensively searched publicly available SARS-CoV-2 biomedical literature to identify drug combinations that could effectively treat COVID-19.

7 Mar 2022

Common rapid antigen tests detect Delta and Omicron SARS-CoV-2 strains effectively

A recent study by US researchers shows how the performance of rapid antigen tests to diagnose severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not inferior among individuals infected with the Omicron variant compared to the Delta variant. The study is currently available on the medRxiv* preprint server while it undergoes peer review.

7 Mar 2022

Polymerase News and Research

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

Current and future perspectives of mRNA technology

Study finds Omicron BA.2 responsible for more but less infectious breakthrough infections

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

Higher SARS-CoV-2 load in morning-collected samples

Bacterial coinfection pervasiveness and antibiotic use in COVID-19 patients

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Delta and Omicron coinfections identified in France

NETosis in COVID-19 and MIS-C

Study explores differentially expressed immune genes for COVID-19 patient stratification

Exploring biomedical literature and clinical trial records to identify new drug combinations for COVID-19 treatment

Common rapid antigen tests detect Delta and Omicron SARS-CoV-2 strains effectively

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Dynamics of SARS-CoV-2 transmission at Purdue University

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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