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Nearly one in three opioid prescriptions in the US not justified, finds analysis

According to a nationwide analysis of physician visit records conducted by a team of researchers at Harvard Medical School and the RAND Corporation, nearly 30 percent of the outpatient opioid prescriptions made out in the United States do not have documented justification for their use.

12 Sep 2018

Scientists develop first DNA-based test for predicting risk of leukemia relapse

A group of Canadian and Korean scientists and physicians have developed the first DNA-based test that allows them to tell which patients will relapse after receiving chemotherapy and a bone marrow transplant, for their acute myeloid leukemia, or AML.

11 Sep 2018

How 'bad' bacteria gain an upper hand in the human gut

A study has revealed that the bacterium C. difficile gains a competitive advantage over protective bacteria in the human gut by producing para-cresol.

11 Sep 2018

Improve reliability, accuracy of drug discovery process with new 3D cell analysis technology

Olympus Corporation today announced the U.S.-only launch of a new 3D cell analysis technology with ability to accurately analyze 3D cell cultures down to the nuclei, improving the reliability and accuracy of the entire drug discovery process, from compound selection to animal experimentation and clinical trials in humans.

From Evident Corporation - Life Sciences 11 Sep 2018

ImmusanT receives JDRF T1D Fund to develop novel vaccine candidate for type 1 diabetes

ImmusanT, Inc., a clinical stage company that is leveraging its Epitope-Specific Immuno-Therapy™ platform to translate and deliver first-in-class peptide-based immune therapies to people living with autoimmune diseases, today announced that it has received an investment from the JDRF T1D Fund, a venture philanthropy fund exclusively devoted to finding and funding the best type 1 diabetes commercial opportunities.

11 Sep 2018

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body's circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma.

11 Sep 2018

Mental imagery techniques regulate pain through opioid-independent mechanisms

Mentally reframing pain as a pleasant experience is an effective regulation strategy that acts independently of the opioid system, finds new human research published in JNeurosci.

11 Sep 2018

Unwitting patients, copycat comments play hidden role in federal rule-making

A proposal to sharply cut a drug discount program that many hospitals rely on drew some 1,400 comments when the Trump administration announced its plan last year. Hundreds appeared to come from patients across the country — pleas from average Americans whose treatments for diseases such as cancer depend on costly medicines.

11 Sep 2018

Cedars-Sinai receives $12 million from NIH to investigate deadly lung conditions

A scientific team led by Cedars-Sinai has been awarded $12 million from the National Institutes of Health to investigate two deadly lung conditions: idiopathic pulmonary fibrosis and chronic lung allograft dysfunction.

11 Sep 2018

FDA and USDA announce joint public meeting on cell cultured food products derived from livestock, poultry

U.S. Secretary of Agriculture Sonny Perdue, DVM and U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D. today announced a joint public meeting to be held on Oct. 23-24, 2018 to discuss the use of cell culture technology to develop products derived from livestock and poultry.

11 Sep 2018

Barrow Institute initiates $50 million effort to seek cure for glioblastoma

Barrow Neurological Institute has initiated a $50 million effort, supported by the single largest research grant in the history of brain tumor research, to seek a cure for the deadliest form of brain cancer.

11 Sep 2018

Vomiting - why so common in kids?

Most kids vomit easily and often copiously and frequently. This is a global phenomenon most parents have resigned themselves to. Researchers have now tried to understand why kids vomit so commonly and if there is actually any reason for parents to panic. An article by Erin Blakemore for NPR looks to answer the question.

11 Sep 2018

Study raises concerns about inappropriate opioid prescribing, lax documentation practices

Nearly 30 percent of outpatient opioid prescriptions in the United States lack documented clinical reasons that justify the use of these potent drugs, according to a national analysis of physician visit records conducted by researchers at Harvard Medical School and the RAND Corporation.

11 Sep 2018

Researchers identify new cancerous cells responsible for acute myeloid leukemia relapse

McMaster University researchers have provided evidence of new cancerous cells they have termed cancer regenerating cells, which are responsible for the return of acute myeloid leukemia after remission.

10 Sep 2018

New framework combines three existing methods to find cancer cell mutations

Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results.

10 Sep 2018

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERT promoter -- the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma -- confers "immortality" on tumor cells, enabling the unchecked cell division that powers their aggressive growth.

10 Sep 2018

Drugs News and Research

Nearly one in three opioid prescriptions in the US not justified, finds analysis

Scientists develop first DNA-based test for predicting risk of leukemia relapse

How 'bad' bacteria gain an upper hand in the human gut

Improve reliability, accuracy of drug discovery process with new 3D cell analysis technology

ImmusanT receives JDRF T1D Fund to develop novel vaccine candidate for type 1 diabetes

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Mental imagery techniques regulate pain through opioid-independent mechanisms

Unwitting patients, copycat comments play hidden role in federal rule-making

Cedars-Sinai receives $12 million from NIH to investigate deadly lung conditions

FDA and USDA announce joint public meeting on cell cultured food products derived from livestock, poultry

Barrow Institute initiates $50 million effort to seek cure for glioblastoma

Vomiting - why so common in kids?

Study raises concerns about inappropriate opioid prescribing, lax documentation practices

Researchers identify new cancerous cells responsible for acute myeloid leukemia relapse

New framework combines three existing methods to find cancer cell mutations

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

Individualized therapies targeting specific features show promise in transforming cancer treatment

Novel finding that links ALS/ataxia to cellular stress opens door to new treatment approaches

FDA approves Cassipa sublingual film for maintenance treatment of opioid dependence

Researchers develop new generation of pain medications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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