Acute Kidney Injury News and Research

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Acute kidney injury (AKI) involves sudden damage to the kidneys or decrease in renal function that occurs over a few hours or days. The severity of the condition can vary from a minor loss of kidney function to kidney failure.

Weekly cisplatin fails to reduce acute toxicity in advanced head and neck cancer

Physicians typically use either a higher dose of cisplatin given every three weeks or a lower dose given weekly in combination with radiation to treat locally advanced head and neck cancer.

29 Sep 2026

High-resolution dataset tracks health impacts of urban heat stress

Heat stress is a leading cause of weather-related deaths and can be especially dangerous in cities where phenomena like urban heat islands drive temperatures higher than surrounding rural areas.

18 Sep 2026

New clinical guidelines standardize kidney replacement therapy in ICU patients

Acute kidney injury (AKI) is a common and severe complication in the intensive care unit (ICU). Due to its high incidence, strong correlation with poor prognosis, and substantial consumption of medical resources, AKI has become one of the central challenges in modern critical care medicine.

17 Sep 2026

Functional angiography outperforms conventional imaging in AIR-STEMI trial

Functional coronary angiography significantly reduced cardiovascular events and improved safety compared with conventional angiography in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease.

29 Aug 2026

Survey reveals gaps in acute kidney injury prevention across intensive care

Acute kidney injury (AKI) remains one of the most frequent and clinically significant complications among critically ill patients, affecting nearly half of those admitted to intensive care units (ICUs).

3 Jul 2026

Severe gum disease linked to early kidney function decline

A growing body of research suggests that the effects of periodontitis extend far beyond the mouth.

2 Jul 2026

Targeting specific immune pathways could prevent severe reperfusion injury

IRI is a shared pathological process in myocardial infarction, ischaemic stroke, acute kidney injury, lung injury, and graft dysfunction after transplantation.

26 Jun 2026

Current chronic kidney disease diagnostic thresholds reflect true patient risk

The thresholds for kidney function currently used to diagnose chronic kidney disease (CKD) reflect a true increase in the risk of serious illness.

4 Jun 2026

Dog daycare outbreak exposes gaps in puppy leptospirosis vaccinations

A 2021 outbreak of leptospirosis that sickened more than 200 dogs in Los Angeles County reveals critical gaps in vaccination practices and raises broader concerns about the spread of the disease between animals and people, according to new research led by the University of California, Davis.

26 May 2026

Air pollution linked to rising kidney disease hospitalization risks

A study supported by FAPESP and published in the journal Scientific Reports showed a strong correlation between the concentration of particulate matter in the air of São Paulo, Brazil – primarily emitted by vehicle fuel combustion – and kidney disease.

13 May 2026

Birth weight predicts kidney function during endurance exercise

Researchers investigate how birth weight determines kidney function changes following prolonged physical activity in different environmental conditions.

7 May 2026

GLP-1 drugs promise wider health benefits, but experts urge caution on use

GLP-1 receptor agonists are reshaping care for type 2 diabetes, obesity, chronic kidney disease, and obstructive sleep apnea, with evidence for glycemic, weight-loss, cardiovascular, and renal benefits. The review urges nurse practitioners to balance expanding clinical promise with careful prescribing, patient education, monitoring, access advocacy, and vigilance for gastrointestinal, endocrine, pregnancy-related, and rare serious risks.

27 Apr 2026

Tirzepatide significantly reduces cardiovascular risk in high-risk patients

Two new studies show that tirzepatide, a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist (RA), significantly reduces cardiovascular risk in high-risk patients, including those undergoing percutaneous coronary intervention (PCI) and those with obesity undergoing transcatheter aortic valve replacement (TAVR).

23 Apr 2026

Transcatheter valve-in-valve procedure improves short-term outcomes in high-risk patients

In patients with a poorly functioning bioprosthetic mitral valve in the heart, a minimally invasive procedure to insert a new valve was associated with a lower rate of death or disabling stroke within one year, compared with patients who underwent standard repeat mitral valve replacement surgery, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026

Taking a GLP-1? Doctors say not to forget about movement and mental health

Severe ankle pain drove Jelon Smart to start taking a weight loss injection a year and a half ago.

26 Mar 2026

Prior COVID infection increases kidney disease risk

Approximately one in seven adults in the United States has kidney disease, where the organs responsible for filtering waste and excess water from the blood are damaged, according to the Centers for Disease Control and Prevention.

25 Feb 2026

Most statin side effects are not backed by trials

Research indicates that many statin therapy side effects are not supported by evidence, suggesting a need for revised labeling to improve treatment decisions.

9 Feb 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Immune checkpoint inhibitors can trigger rare immune thrombocytopenia in cancer patients

Researchers led by investigators at Mass General Brigham have published valuable information about a rare but serious complication of anti-cancer immunotherapy, providing the first large-scale description of its risk factors and clinical course, and underscoring the importance of early diagnosis and treatment.

12 Dec 2025

Retrospective analysis shows mortality rates and risk factors after prosthetic heart valve surgeries

Mechanical valve replacement is a primary treatment for rheumatic heart disease, yet prosthesis-related adverse outcomes remain underreported in India.

25 Nov 2025