Adenocarcinoma News and Research

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Adenocarcinoma is cancer that begins in cells that line certain internal organs and that have gland-like (secretory) properties.

Bile DNA sequencing helps identify hidden pancreatobiliary tumors

Distinguishing malignant from benign biliary strictures remains a major clinical challenge. Endoscopic retrograde cholangiopancreatography (ERCP)-guided cytology and biopsy may be inconclusive, particularly in early-stage disease or when tissue is scarce.

29 Sep 2026

Five-session SBRT preserves quality of life before pancreatic cancer surgery

Patients preparing for pancreatic cancer surgery maintained better physical function and experienced less fatigue with five treatments of stereotactic body radiation therapy (SBRT) than with 28 treatments of conventional radiation therapy given with chemotherapy, according to a randomized phase 2 clinical trial.

28 Sep 2026

Sugary drinks stood out in this stomach cancer study, but diet drinks did not

In two large US prospective cohorts, consuming more than one sugar-sweetened beverage a day was associated with higher gastric cancer incidence compared with consuming less than one serving a month. Artificially sweetened beverages were not associated with gastric cancer incidence, and the authors called for further studies to confirm the findings and clarify possible biological mechanisms.

21 Sep 2026

Novel blood test could detect pancreatic cancer at its earliest stages

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the country, led the development of a new, investigational blood test that could detect pancreatic cancer at its earliest stages, when the disease is more treatable and potentially curable.

16 Sep 2026

Like your tea or coffee very hot? A study of nearly 1 million adults found a striking cancer link

In pooled prospective data from 977,282 UK adults, preferring tea or coffee “very hot” was associated with more than threefold higher risk of esophageal squamous cell carcinoma compared with preferring drinks “warm,” while drink temperature showed no material association with adenocarcinoma risk. Consuming six or more hot drinks daily was independently associated with higher squamous cell carcinoma risk, and modeling estimated that about 440 UK cases each year could be prevented by switching from “very hot” to “hot” drinks if the association is causal.

14 Sep 2026

Laser therapy offers new hope for inoperable pancreatic tumors

UCI Health, the clinical enterprise of the University of California, Irvine, is conducting a first-in-human, phase 1 clinical trial using laser light to target localized but inoperable pancreatic tumors to help patients become cancer free.

10 Sep 2026

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

The U.S. Food and Drug Administration (FDA) has approved daraxonrasib, an oral multi-selective RAS(ON) inhibitor, for adults with metastatic pancreatic adenocarcinoma who have received at least one prior systemic therapy or are not candidates for multiagent systemic therapy.

From Dana-Farber Cancer Institute, Inc. 29 Aug 2026

Study identifies KRAS G12C as a precision-medicine target in genitourinary cancers

A new research paper was published in Volume 17 of Oncotarget on August 19, 2026, titled "Incidence of KRAS G12C mutations in genitourinary malignancies; emerging target in precision medicine."

28 Aug 2026

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

27 Aug 2026

New discovery helps identify colorectal cancer patients at risk for metastasis

Researchers from the University of Turku in Finland and Gustave Roussy Institute in France have discovered a molecular mechanism that regulates whether the cells of an aggressive colorectal cancer are conventional or inverted when they spread in the body.

25 Aug 2026

A decades-long study raises questions about sugary drinks and stomach cancer

A large prospective U.S. study followed more than 111,000 adults to examine whether sugar-sweetened and artificially sweetened beverage intake was associated with gastric cancer incidence. Researchers identified 278 gastric cancer cases over 3.2 million person-years and found that associations differed according to beverage type and level of consumption.

19 Aug 2026

Computational pipeline uncovers subtype specific targets for cervical cancer

A new study presents a multi-layered strategy for identifying cell-surface targets that could help guide more precise antibody-drug conjugate (ADC) development for cervical cancer, with different targets showing distinct potential across tumor subtypes.

17 Aug 2026

AI model predicts cancer subtype, genetic mutations, and survival outcomes across 32 solid tumors

Researchers have developed a novel AI model that can analyze a routine whole histopathology image and simultaneously predict cancer subtype, specific genetic mutations, and survival outcomes across 32 different solid cancers rather than focusing on a single cancer type.

13 Aug 2026

Circular eccDNA shows potential to predict early-stage LUAD recurrence

LUAD is the most common histological subtype of lung cancer. Although surgery can be curative for patients diagnosed at an early stage, approximately 30%-50% develop recurrence or aggressive metastasis within five years.

10 Aug 2026

New drug delivers promising survival gains in pancreatic cancer

About 90% of people with pancreatic cancer have pancreatic ductal adenocarcinoma (PDAC), which is driven by an activating mutation in the KRAS gene.

9 Aug 2026

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

A growing body of evidence suggests that a rare epithelial cell type known as the tuft cell may play a far more significant role in cancer than previously recognized.

6 Aug 2026

New study explores cholesterol-driven survival mechanisms in pancreatic cancer

A University of Oklahoma researcher has received a five-year, $2 million grant from the National Cancer Institute to investigate how pancreatic cancer uses cholesterol to survive chemotherapy.

6 Aug 2026

Experimental drug CS18 shows promise for overcoming cancer treatment resistance

Researchers at Baylor College of Medicine have developed a drug called CS18 that disrupts the ability of cancer cells to survive therapy. The findings, published in Science Advances, support exploring the possibility of using CS18 to treat human cancer in the future.

5 Aug 2026

Study reveals sex-based protein differences across lung cancer types

Biological sex factors into cancer in ways you might not expect. In lung cancer, a form called squamous cell carcinoma disproportionately affects males while adenocarcinoma occurs more frequently in females.

21 Jul 2026

Exercise oncology could unlock new therapeutic pathways against cancer

Regular exercise is associated with improved outcomes for many patients with cancer, yet those with advanced disease may be unable to participate in exercise-based interventions.

20 Jul 2026