Adenocarcinoma News and Research

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Adenocarcinoma is cancer that begins in cells that line certain internal organs and that have gland-like (secretory) properties.

DNA methylation profiling stratifies recurrence risk in low-grade endometrial cancer

Molecular diagnostic approaches are expanding what information is available for clinicians and laboratory professionals, including uncovering antimicrobial resistance, identifying pathogens missed by conventional methods, revealing cancer recurrence risks and characterizing complex tumor biology.

13 Nov 2026

Scientists identify metabolic pathway driving lung cancer lymph node metastasis

Metabolic reprogramming plays a critical role in shaping the adaptive capabilities of malignant cells during dissemination.

12 Nov 2026

Clinical trial of triple combination therapy reveals clues to lung cancer treatment resistance

In a new clinical trial, researchers have interrogated how patients with an aggressive form of lung cancer respond to treatment with a triple combination therapy.

12 Nov 2026

Blocking complement factor B halts pancreatic cancer growth

Researchers have identified a promising new target in the treatment of pancreatic cancer. A new study in The American Journal of Pathology, published by Elsevier, demonstrates that blocking complement factor B (CFB), a pivotal enzyme in the alternative complement pathway, halts cancer growth and alters the tumor microenvironment.

9 Nov 2026

Study uncovers translation control mechanisms driving tumor growth and therapy resistance

Decoding of messenger RNA (mRNA) occurs during translation, the vital cellular process that builds proteins. Errors in this process are known to lead to cancer growth.

3 Nov 2026

Targeting ANO6 protein weakens pancreatic cancer and boosts immunity

Fox Chase Cancer Center researchers identified a potential therapeutic target for pancreatic cancer after showing that tumor growth can be slowed and immune suppression can be reduced in preclinical trials by blocking a particular protein, called anoctamin 6 (ANO6).

30 Oct 2026

New study identifies potential targets for KRAS-related treatment resistance

Decoding of messenger RNA (mRNA) occurs during translation, the vital cellular process that builds proteins. Errors in this process are known to lead to cancer growth.

29 Oct 2026

Targeted drug extends survival across diverse pancreatic cancer patient groups

A new analysis of a phase 3 clinical trial found that the targeted drug daraxonrasib improved survival compared with standard chemotherapy across multiple groups of patients with advanced pancreatic cancer, including those with different RAS mutations and those without an identified RAS mutation.

23 Oct 2026

CT scans reveal body composition changes preceding pancreatic cancer diagnosis

People who develop pancreatic cancer experience measurable changes in body composition years before diagnosis that differ from those seen in similar individuals without cancer, according to a Mayo Clinic study led by former Mayo Clinic research fellow, Aleksander Bogdanski and published in Pancreatology.

20 Oct 2026

Scientists studied diet and lung cancer in 95,612 adults. One eating pattern stood out

A prospective study of 95,612 U.S. adults found that those with the highest sulfur microbial diet scores had a 23% higher adjusted lung cancer incidence hazard and a 19% higher lung cancer-related mortality hazard than those with the lowest scores. However, the associations weakened after accounting for overall dietary quality and competing causes of death, and the findings do not establish a causal relationship.

13 Oct 2026

Pancreatic cancer cells continuously reshape DNA to evade treatment

A new analysis of nearly half a million cells from dozens of pancreatic tumors, led by researchers at UC San Diego Moores Cancer Center and New York University (NYU), reveals how pancreatic cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment.

13 Oct 2026

Single-cell analysis reveals how pancreatic cancer evades treatment

An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment for one of the deadliest forms of cancer.

13 Oct 2026

New research unveils role of innate immune system in pancreatic cancer

Researchers from Adelaide University have demonstrated that blocking a specific immune system gene can reduce pancreatic cancer tumor formation.

9 Oct 2026

High expression of CTDNEP1 gene linked to poorer kidney cancer survival

Renal cell carcinoma (RCC) is the most common form of kidney cancer, accounting for about 90% of kidney cancers.

7 Oct 2026

Cigarette smoke alters lung stem cells to drive specific cancers

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene alterations and ultimately helps determine the type of lung cancer that develops.

6 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Bile DNA sequencing helps identify hidden pancreatobiliary tumors

Distinguishing malignant from benign biliary strictures remains a major clinical challenge. Endoscopic retrograde cholangiopancreatography (ERCP)-guided cytology and biopsy may be inconclusive, particularly in early-stage disease or when tissue is scarce.

29 Sep 2026

Five-session SBRT preserves quality of life before pancreatic cancer surgery

Patients preparing for pancreatic cancer surgery maintained better physical function and experienced less fatigue with five treatments of stereotactic body radiation therapy (SBRT) than with 28 treatments of conventional radiation therapy given with chemotherapy, according to a randomized phase 2 clinical trial.

28 Sep 2026

Sugary drinks stood out in this stomach cancer study, but diet drinks did not

In two large US prospective cohorts, consuming more than one sugar-sweetened beverage a day was associated with higher gastric cancer incidence compared with consuming less than one serving a month. Artificially sweetened beverages were not associated with gastric cancer incidence, and the authors called for further studies to confirm the findings and clarify possible biological mechanisms.

21 Sep 2026

Novel blood test could detect pancreatic cancer at its earliest stages

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the country, led the development of a new, investigational blood test that could detect pancreatic cancer at its earliest stages, when the disease is more treatable and potentially curable.

16 Sep 2026