Antihistamines News and Research

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Common allergy medications offer no real relief for eczema patients

It's typical for someone looking for relief from dry, itchy, red and irritated skin – also known as eczema or atopic dermatitis – to turn to common allergy medications called antihistamines.

30 Jul 2026

Study questions antihistamine use for managing eczema symptoms

Adding oral antihistamines to existing eczema treatments is unlikely to lead to clinically important reductions in eczema and itch severity, and may not reduce sleep disturbance or flare-ups, finds a review of the latest trial evidence published by The BMJ today.

29 Jul 2026

Antihistamines show modest benefits for long Covid fatigue treatment

Over-the-counter antihistamines and a prescription anti-inflammatory drug both have a small benefit in reducing long Covid fatigue among people receiving care from specialist long Covid clinics, according to new findings from a large clinical trial led by UCL and UCLH.

8 Jul 2026

Study reveals how glial cells regulate brain injury and recovery

Traumatic brain injury (TBI) affects millions of people worldwide every year and remains a major cause of long-term disability, cognitive decline, and neurological complications.

8 Jul 2026

Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment

Nasal commensal viruses may worsen allergic rhinitis by activating type I IFN-linked neutrophils and NET formation. Ribavirin reduced nasal viral abundance and improved symptoms in mice and in a small phase 2 trial.

28 Jun 2026

Review explores diagnosis and management of perioperative anaphylaxis during anesthesia

Perioperative anaphylaxis is a rare, life‑threatening condition during anesthesia. The unique setting – multiple drugs, patient draping, and altered physiology – causes higher mortality than anaphylaxis elsewhere.

29 May 2026

What medicine-exposed rats reveal about the next urban zoonotic threat

Researchers found that more than half of urban rats sampled from low-income communities in Salvador, Brazil, carried active pharmaceutical ingredients in their brain tissue. These pollutants were associated with altered zoonotic infection patterns, including lower Leptospira infection probability in rats carrying azithromycin and higher Capillaria infection probability in rats carrying citalopram.

22 May 2026

Experts establish standardized protocols for pediatric recurrent wheezing diagnosis

Recurrent wheezing, a respiratory disorder, is caused by the narrowing of the airways, mainly affecting children aged less than 5 years.

26 Mar 2026

High use of anticholinergic drugs linked to increased cardiovascular disease risk

People who use drugs with anticholinergic effects, including certain antidepressants, drugs for urinary incontinence and common antihistamines, are at higher risk of developing cardiovascular disease.

5 Mar 2026

Thermodynamic insights into histamine H1 receptor ligand binding

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs.

13 Feb 2026

Gut bacteria produce immune-boosting compounds in response to tetracyclines

The microbes inside our bodies not only help break down food but also impact our health. Yet their precise influence is not always understood, especially in the presence of prescription drugs.

3 Dec 2025

Black cumin: A promising natural agent with potential against chronic diseases

Black cumin seeds contain diverse secondary metabolites, including thymoquinone, flavonoids, triterpenoids and alkaloids, that demonstrate broad antimicrobial, antioxidant, anti-inflammatory and anticancer activity. Early preclinical and limited clinical evidence shows therapeutic potential across chronic diseases, supported by mechanistic and structure activity relationship findings.

24 Nov 2025

Kennedy sharpens vaccine attacks, without scientific backing

As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body's immune response.

24 Nov 2025

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

New study highlights the impact of pediatric integrative medicine services

A new study conducted by University Hospitals Connor Whole Health highlights the impact of pediatric integrative medicine services.

5 Nov 2025

First-generation antihistamines increase delirium risk in older hospitalized patients

An analysis in the Journal of the American Geriatrics Society reveals that older inpatients admitted to physicians who prescribe higher amounts of first-generation antihistamines face an elevated risk of delirium while in the hospital.

22 Oct 2025

Rising misuse of over-the-counter antihistamines puts teens at serious health risk

Adolescents and young adults are misusing common over-the-counter antihistamines, putting them at risk of severe health outcomes including heart arrythmias, seizures or death, according to research presented during the American Academy of Pediatrics 2025 National Conference & Exhibition at the Colorado Convention Center from Sept. 26-30.

26 Sep 2025

Why are more older people dying after falls?

For a while, walking the dog felt hazardous. Earl Vickers was accustomed to taking Molly, his shepherd-boxer-something-else mix, for strolls on the beach or around his neighborhood in Seaside, California. A few years ago, though, he started to experience problems staying upright.

15 Sep 2025

Can an allergy spray help prevent COVID-19?

Researchers determine the efficacy and safety of azelastine nasal spray for preventing SARS-CoV-2 infection in healthy adults.

8 Sep 2025

Gut mast cells produce key molecules driving food allergy anaphylaxis

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause difficulty breathing, a dangerous drop in blood pressure and even death.

28 Aug 2025