Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Refractory lichen planus-like lesions reveal underlying systemic T-cell lymphoma

A 61-year-old man had a 2-year history of painful mucosal lesions and pruritic violaceous plaques on the trunk and extremities.

6 Nov 2026

Women with DCIS may not need routine imaging after double mastectomy

Women who have undergone a double mastectomy to treat ductal carcinoma in situ (DCIS), a noninvasive form of breast cancer also known as stage 0 breast cancer, may not benefit from routine mammograms or other breast imaging after surgery, according to a new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.

4 Nov 2026

Advanced imaging tool improves detection of residual multiple myeloma disease

A targeted immunoPET scan detected active multiple myeloma that standard PET/CT scans and blood tests missed, a finding that could help doctors more accurately map disease, guide treatment decisions and confirm whether cancer remains after therapy.

3 Nov 2026

Gene therapy successfully corrects genetic defect in alpha-1 antitrypsin deficiency

In a landmark achievement in the field of genetic medicine, researchers have reported the very first published case in a peer-reviewed journal of a successful clinical treatment of a patient with alpha-1 antitrypsin deficiency (PiZZ) using in vivo gene therapy.

2 Nov 2026

New pediatric consensus standardizes surgical management of Wilms tumor

WT outcomes have improved substantially through progress in molecular diagnosis, chemotherapy, radiotherapy, and surgery. Yet surgical management remains inconsistent, especially for large tumors, adjacent-organ invasion, intravascular extension, nephron-sparing surgery (NSS), and lymph node biopsy.

2 Nov 2026

Major studies identify accurate non-invasive tests for liver disease

Two major international studies have delivered the strongest evidence to date on which non-invasive tests can accurately diagnose and measure the severity of metabolic dysfunction-associated steatotic liver disease (MASLD) and its more severe form, MASH, reducing reliance on liver biopsy.

29 Oct 2026

Soft robotic enteroscope offers a new approach to small intestine examination

An innovative robotic device inspired by snake movement could someday help gastroenterologists diagnose and treat inflammatory bowel disease (IBD) and other disorders of the small intestine and remove small polyps while reducing trauma to the organ's delicate tissues.

28 Oct 2026

Landmark studies map how genetic differences drive human diseases

In three landmark studies published in Nature today, Australian researchers have made major advances in our understanding of how genetic differences between people influence disease.

28 Oct 2026

Cerebrospinal fluid liquid biopsy detects tumor DNA in complex brain cases

A Mayo Clinic study published in the Journal of Neuro-Oncology suggests that analyzing DNA in cerebrospinal fluid could provide another source of information when MRI cannot provide a clear brain tumor diagnosis or obtaining tissue through biopsy is difficult or potentially unsafe.

27 Oct 2026

Doctors explain why breast cancer screening should start at age 40

Advances in breast cancer screening and treatment are helping doctors detect the disease earlier, tailor therapies to individual patients and, in some cases, spare women from unnecessary chemotherapy, radiation and surgery.

24 Oct 2026

Standardized protocol enables safer kidney biopsies in high-risk patients

Results from a prospective study reveal that with standardized precautions, even high-risk patients may safely undergo a kidney biopsy, a cornerstone of kidney diagnostics that is often perceived as dangerous in certain vulnerable patient populations.

22 Oct 2026

AI scoring tool may guide skin biopsy decision

Mayo Clinic researchers have found that an artificial intelligence (AI) tool may provide dermatologists with additional information to help assess whether skin lesions are cancerous and inform their clinical decisions about whether to biopsy or monitor them, according to a study published in Mayo Clinic Proceedings.

22 Oct 2026

AGA/AASLD joint guideline evaluates newer medications for primary biliary cholangitis

For the first time, a joint guideline from the American Gastroenterological Association (AGA) and American Association for the Study of Liver Diseases (AASLD) evaluates newer medications for primary biliary cholangitis (PBC), the most common cholestatic disease in adults.

22 Oct 2026

Liquid biopsy reliably detects early-stage lung cancer recurrence risk

Despite advances in early-stage lung cancer treatment, a significant number of patients experience disease recurrence after surgery or initial therapy.

20 Oct 2026

New trial aims to test whether a blood test can detect breast cancer earlier than mammograms

Researchers at USC Norris Comprehensive Cancer Center, part of Keck Medicine of USC, have launched a clinical trial to evaluate whether a blood test can help detect breast cancer earlier than mammograms alone.

15 Oct 2026

New AI tool distinguishes Ewing sarcoma with high accuracy

A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated an artificial intelligence (AI) system capable of distinguishing Ewing sarcoma from other morphologically similar tumours with high accuracy.

13 Oct 2026

Mursla Bio publishes peer-reviewed validation of tissue-specific extracellular vesicle platform for liquid biopsy

Mursla Bio, a precision medicine and diagnostics company built on tissue-specific extracellular vesicles (TS-EVs), today announced publication of a peer-reviewed study in the Journal of Extracellular Vesicles (impact factor 21.7), the founding journal of the International Society for Extracellular Vesicles. This validates the TS-EV platform for a new class of liquid biopsy: the multiomic disease biology of living cells in a chosen tissue, read from blood, starting with the liver.

From Mursla Bio 13 Oct 2026

Study reveals continued care delays among patients with young-onset breast cancer

In an analysis of data on adolescents and young adults with breast cancer, lower income and younger age were linked with delays in care.

12 Oct 2026

Automated ultrasound offers reliable alternative for screening women with dense breasts

A new study in the Journal of the American College of Radiology, published by Elsevier, has found that automated breast ultrasound (ABUS) and handheld ultrasound (HHUS) had similar cancer detection rates in women with dense breasts, while ABUS had a lower false-positive rate.

8 Oct 2026

New AI model detects heart transplant rejection without biopsies

By analyzing heart rhythm recordings and blood tests, artificial intelligence may accurately flag when a transplant patient's body starts attacking a donated heart, a new study suggests.

6 Oct 2026

Biopsy News and Research

Further Reading

Refractory lichen planus-like lesions reveal underlying systemic T-cell lymphoma

Women with DCIS may not need routine imaging after double mastectomy

Advanced imaging tool improves detection of residual multiple myeloma disease

Gene therapy successfully corrects genetic defect in alpha-1 antitrypsin deficiency

New pediatric consensus standardizes surgical management of Wilms tumor

Major studies identify accurate non-invasive tests for liver disease

Soft robotic enteroscope offers a new approach to small intestine examination

Landmark studies map how genetic differences drive human diseases

Cerebrospinal fluid liquid biopsy detects tumor DNA in complex brain cases

Doctors explain why breast cancer screening should start at age 40

Standardized protocol enables safer kidney biopsies in high-risk patients

AI scoring tool may guide skin biopsy decision

AGA/AASLD joint guideline evaluates newer medications for primary biliary cholangitis

Liquid biopsy reliably detects early-stage lung cancer recurrence risk

New trial aims to test whether a blood test can detect breast cancer earlier than mammograms

New AI tool distinguishes Ewing sarcoma with high accuracy

Mursla Bio publishes peer-reviewed validation of tissue-specific extracellular vesicle platform for liquid biopsy

Study reveals continued care delays among patients with young-onset breast cancer

Automated ultrasound offers reliable alternative for screening women with dense breasts

New AI model detects heart transplant rejection without biopsies

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