Coeliac Disease News and Research

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Immune cell defects may drive celiac disease development

New research from the Snow Centre for Immune Health is challenging long-held assumptions about autoimmune disease, revealing that coeliac disease may be driven not just by an overactive immune system, but by subtle defects in how immune cells function.

9 Jun 2026

Body weight and genes directly alter gut microbiota composition

Your body weight and genes influence the types of bacteria you have in your gut. In turn, this appears to affect the risk of developing conditions such as coeliac disease and haemorrhoids.

18 May 2026

A breakthrough molecular discovery could neutralize gluten and protect coeliac patients

A research project led by the Institute for Research in Nutrition and Food Safety (INSA) and the Faculty of Pharmacy and Food Sciences at the University of Barcelona, together with the Molecular Biology Institute of Barcelona (IBMB) of the CSIC (which stands for Consejo Superior de Investigaciones Científicas), has successfully designed and tested a gluten-degrading molecule that is a promising ally in the management of coeliac disease, an autoimmune disease whose symptoms are triggered by the consumption of gluten and other prolamins found in cereals.

14 May 2026

Experimental drug ZED1227 protects the whole body from gluten damage

An experimental drug may in future provide a new form of protection for people with celiac disease.

28 Apr 2026

Viral RNA modifications trigger celiac inflammation

An EHU study indicates that a drug already approved for use in humans could help to reduce the inflammation associated with celiac disease.

24 Feb 2026

Dietary intervention eases celiac symptoms in children but not quality of life

The Gluten3S research group launched a dietary intervention with children who had recently been diagnosed with celiac disease.

14 Jan 2026

Fructans and ATIs impact digestive health in beer

The GLUTEN3S research group of the University of the Basque Country (EHU) has identified the presence of fructans and amylase/trypsin inhibitor (ATI) proteins in gluten-free beers made from barley, compounds that can cause digestive symptoms in sensitive individuals. Its content is comparable to that of traditional beers containing gluten, according to a study published in the Journal of Food Composition and Analysis.

16 Dec 2025

New findings show why the human intestine uniquely presents gluten to T cells

Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity and specialized machinery for processing gluten. Their ability to deamidate and present gliadin peptides positions them as key initiators of immune responses relevant to coeliac disease.

11 Dec 2025

White bread vs wholegrain: which one is actually better for your health?

This review dispels common myths about white and wholegrain bread by examining their composition processing and health effects. It concludes that while wholegrain breads offer added benefits white bread remains a safe affordable and nutritionally meaningful staple when fortified.

11 Dec 2025

Study shows gluten sensitivity is driven by gut–brain interactions rather than gluten

A landmark study has revealed that gluten sensitivity, which affects approximately 10 per cent of the global population, is not actually about gluten but part of the way the gut and brain interact.

21 Nov 2025

Study highlights high prevalence of non-coeliac gluten sensitivity lacking clear markers

Around one in ten people worldwide report gastrointestinal and other symptoms such as fatigue and headache after eating foods containing gluten or wheat despite not having a diagnosis of either coeliac disease or wheat allergy, finds a large systematic review and meta-analysis published online in Gut.

29 Oct 2025

Night shift work may raise risk of irritable bowel syndrome

The study indicates that night shift work increases irritable bowel syndrome risk, particularly among those with obesity, due to circadian rhythm disturbances.

22 Oct 2025

Study: More expectant mothers begin pregnancy with autoimmune conditions

Thousands more UK women who are having children have been diagnosed with an autoimmune condition now compared to the beginning of the millennium.

2 Jun 2025

$Discovery of mutated immune cell clones could point to improved treatment for refractory celiac disease$

Discovery of mutated immune cell clones could point to improved treatment for refractory celiac disease

Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease.

15 May 2025

AI matches pathologists in diagnosing celiac disease

A machine learning algorithm developed by Cambridge scientists was able to correctly identify in 97 cases out of 100 whether or not an individual had coeliac disease based on their biopsy, new research has shown.

27 Mar 2025

AI is as good as pathologists at diagnosing coeliac disease, study finds

26 Mar 2025

BIOHIT secures European distribution rights for Biomedal’s gluten immunogenic peptide tests

BIOHIT is excited to announce an agreement with Biomedal to supply its iVYLISA, iVYCHECK and GlutenDetect gluten immunogenic peptide (GIP) tests.

17 Jan 2025

Dexter software platform reveals connection between early life trauma and immune disorders

University of Birmingham venture Dexter has demonstrated the power of its Dexter software platform in a study showing that people whose childhoods featured abuse, neglect or domestic abuse carry a significantly increased risk of developing rheumatoid arthritis or psoriasis in later life.

15 Jan 2025

MRI study offers new insights into celiac disease treatment

Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with coeliac disease, which could be the first step towards finding new ways of treating the condition.

6 Dec 2024

Genetic and environmental drivers shape early type 1 diabetes risk in children

Researchers from the TEDDY study highlight how specific genetic and environmental factors may drive early autoimmunity linked to type 1 diabetes in children, emphasizing distinct patterns for different autoantibodies.

5 Nov 2024