Coronary Disease News and Research

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TAVI-first strategy proves noninferior to PCI-first approach in new trial

A TAVI-first strategy was noninferior to a PCI-first strategy after one years' follow-up, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

30 Aug 2026

Trial shows antiplatelet therapy needs personalization after stent implantation

Antiplatelet monotherapy reduced bleeding but dual therapy provided greater cardiovascular event protection in patients at high ischemic risk who had undergone stent implantation 12 months earlier.

29 Aug 2026

Antiretroviral therapy reduces biological aging in people living with HIV

A major study presented today at ESCMID Global 2026 has found that antiretroviral therapy (ART) reduces accelerated biological ageing in people with HIV (PWH) by nearly four years, a finding that could transform how clinicians monitor HIV treatment and long-term health outcomes.

20 Apr 2026

Left-ventricular unloading during angioplasty fails to improve patient outcomes

The first randomized trial to compare standard percutaneous coronary intervention (PCI), also known as coronary angioplasty, with PCI accompanied by the use of a temporary, miniaturized pump to support the heart in patients with both severe coronary heart disease and moderate to severe heart failure found no significant difference between the two approaches.

29 Mar 2026

Predictive power of C-reactive protein shifts based on cirrhosis or coronary disease

A new study reveals that the predictive power of key inflammatory markers, such as C-reactive protein, shifts fundamentally depending on whether a patient suffers from cirrhosis or acute/chronic coronary disease.

18 Feb 2026

Frailty impacts heart attack survival differently by sex

Pioneering research from the University of Leicester and NIHR challenges the 'one-size-fits-all' approach to heart attack care, adding critical nuance to the debate on sex disparities.

18 Feb 2026

Men develop premature heart disease earlier than women

The study uncovers critical insights into sex-based heart disease risks, highlighting young adulthood as key for effective cardiovascular health interventions.

2 Feb 2026

New evidence supports ablation for high-risk patients with AFib and sleep apnea

Obstructive sleep apnea and atrial fibrillation are two conditions that share a potentially deadly link. Having one increases the odds of developing the other, and together, the breathing difficulties of sleep apnea combined with the irregular heartbeat of atrial fibrillation (AFib) can result in life-threatening cardiovascular risks.

1 Dec 2025

Comparative study finds higher rates of adverse events with ticagrelor

One year of treatment with either of two strong blood-thinning medications—ticagrelor and prasugrel—by people with type 1 or type 2 diabetes who had a drug-eluting stent placed in their heart to treat coronary artery blockages did not offer the same level of benefit to prevent stent clotting, heart attacks, and bleeding complications, according to findings presented during a preliminary late-breaking science session during the American Heart Association's Scientific Sessions 2025 in New Orleans on November 10.

10 Nov 2025

Prasugrel shows advantage over ticagrelor in diabetic patients after stent placement

One year of dual antiplatelet therapy with one of two potent P2Y12 inhibitors-ticagrelor or prasugrel-in people with Type 1 or Type 2 diabetes who had received a drug-eluting stent did not offer the same level of benefit at preventing stent clotting, heart attacks and bleeding complications, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease, according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

29 Aug 2025

Harnessing saliva for precision medicine and early disease diagnosis

A research team led by the University of the Basque Country (Euskal Herriko Unibertsitatea, EHU) has identified hundreds of molecular markers in saliva that could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases.

26 Jun 2025

Study finds fewer H. pylori infections among Parkinson’s patients

A large case-control study from China found that people with Parkinson’s disease were significantly less likely to test positive for Helicobacter pylori infection compared to controls. The findings suggest a potential protective link between this common stomach bacterium and Parkinson’s disease, though causality remains unproven.

15 May 2025

Palliative care for cardiovascular conditions may help relieve symptoms and improve quality of life

Palliative care may help relieve symptoms and improve quality of life for people with cardiovascular disease and ensure that treatment is aligned with the patient's personal beliefs and values throughout all stages of illness, whether they are hospitalized in a cardiac intensive care unit or receiving outpatient care, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

15 May 2025

Study aims to determine best method for statin prescription in coronary heart disease

A new study by researchers at Intermountain Health in Salt Lake City aims to determine the best method to screen and evaluate patients who are at risk of developing coronary heart disease and which patients would benefit from taking a statin medication to lower cholesterol.

29 Mar 2025

New guidelines allow select athletes with heart abnormalities to participate in competitive sports

Recent research suggests that select athletes with cardiovascular abnormalities may be able to safely participate in competitive sports after shared decision-making with their clinicians about potential risks, according to a joint scientific statement published today in the American Heart Association's flagship, peer-reviewed journal Circulation and simultaneously in JACC, the flagship journal of the American College of Cardiology.

21 Feb 2025

New risk score accurately predicts cardiovascular events in women

A new risk score accurately predicts and categorizes the risk of major adverse cardiovascular events, such as heart attack, in women. The findings were published today in Radiology: Cardiothoracic Imaging, a journal of the Radiological Society of North America (RSNA).

5 Dec 2024

AI tool detects heart disease in CT scans originally meant for other purposes

With the help of an artificial intelligence (AI) tool, computed tomography (CT) scans taken to look for tumors or bleeding or infections, also revealed calcium buildup in arteries, a sign of worsening cardiovascular disease.

4 Dec 2024

Air pollution spurs inflammation in heart failure patients

A new study by heart researchers at Intermountain Health in Salt Lake City finds that patients with heart disease, specifically those with heart failure, are especially vulnerable to the impacts of air pollution and poor air quality and can take steps to protect themselves.

18 Nov 2024

Socioeconomic disadvantage predicts poorer outcomes for heart transplant patients

Heart transplant patients who live in socioeconomically disadvantaged areas are more likely to experience post-surgical complications and die within five years than patients who live in more advantaged areas, even when those patients were transplanted at topnotch high-volume hospitals, new UCLA research suggests.

1 Oct 2024