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Study maps enzyme target for potential treatment of rare genetic disorder

Researchers at the Icahn School of Medicine at Mount Sinai have mapped an enzyme that could be targeted to develop new treatments for glutaric aciduria type 1 (GA1), a rare genetic disorder that can lead to brain damage, revealing new details about how the enzyme works and how its activity is controlled.

13 Nov 2026

Phage protein study opens new path for future antibiotics

Drug-resistant bacteria are becoming more common worldwide, posing a major public health challenge. Addressing this problem requires finding new ways to eliminate bacteria, which in turn requires analyzing essential cellular processes that could serve as targets for future antibiotics.

9 Nov 2026

Study uncovers translation control mechanisms driving tumor growth and therapy resistance

Decoding of messenger RNA (mRNA) occurs during translation, the vital cellular process that builds proteins. Errors in this process are known to lead to cancer growth.

3 Nov 2026

New study identifies potential targets for KRAS-related treatment resistance

Decoding of messenger RNA (mRNA) occurs during translation, the vital cellular process that builds proteins. Errors in this process are known to lead to cancer growth.

29 Oct 2026

New research center aims to accelerate hepatitis C vaccine development

The shifty hepatitis C virus (HCV) has a knack for outmaneuvering the immune system. Its secret is an especially high mutation rate, which has generated an abundance of viral variants with extreme genetic diversity.

27 Oct 2026

Amyloid fibers help sperm deliver RNA to mouse embryos

Researchers identified RNA-associated amyloid fibrils in human seminal fluid and demonstrated that synthetic PAP fibrils could enter mammalian sperm. In mouse IVF experiments, these fibrils helped sperm deliver RNA to embryos, where the detected reporter-protein signal was at least tenfold higher than without fibril exposure.

27 Oct 2026

The impact of vibration on microscopy

Environmental vibration affects microscopy image quality, experimental accuracy and reproducibility, and how isolation technologies can help.

From TMC Vibration Control 27 Oct 2026

Researchers capture clear images of complex cancer drug building enzyme

A joint research group led by Ryo Tanifuji and Hiroki Oguri from the University of Tokyo and Yoshikazu Tanaka from Tohoku University has successfully visualized SacC, an enzyme that plays a key role in building the complex five-ring core of safracin B.

19 Oct 2026

Light-activated experimental opioid eliminates dangerous side effects

Opioid painkillers are some of the strongest analgesic medicines, but they are also the riskiest owing to a range of side effects, including addiction.

15 Oct 2026

Scientists identify the neuroblastoma cells that signal poor outcomes

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood.

10 Oct 2026

Major global alliance invests billions to build predictive AI models of biology

Biohub, the U.S. Department of Energy, the National Institutes of Health, and new funding partners today announced a major expansion of an international effort to generate and make accessible the data enabling predictive AI models of biology.

7 Oct 2026

Before the first bite: A missing gut protein may set the stage for peanut allergy

For most people, a peanut butter sandwich poses no threat. But for the roughly 1.6 million children in the United States with peanut allergy, exposure can trigger a life-threatening reaction.

6 Oct 2026

Tau modifications shape filament structures in neurodegenerative diseases

In neurodegenerative diseases such as Alzheimer's disease, progressive neuronal damage is associated with the accumulation of abnormal tau filaments in the brain.

6 Oct 2026

Lipid signaling pathway helps cells survive bacterial toxin damage

Epithelial cells form the body's frontline barriers, helping keep microbes, toxins, and other harmful substances out.

5 Oct 2026

New study reveals how VEGF-C amplifies lymphangiogenic signaling

Lymphatic vessels act as the body's "drainage system," collecting excess fluid from tissues. When lymphatic drainage is impaired because lymphatic vessels are underdeveloped, damaged, or dysfunctional, lymphedema can develop, causing swelling, particularly in the arms and legs.

1 Oct 2026

New study uncovers breakthrough window to prevent brain metastasis

Metastasis, the process by which a tumor spreads throughout the body, is associated with the majority of cancer deaths.

29 Sep 2026

Mediterranean rockrose extract shows strong potential against skin fungi

A polyphenol-rich extract from Cistus salviifolius, a Mediterranean rockrose species traditionally used to treat skin conditions, has shown fungicidal activity against several dermatophytes, the fungi responsible for superficial infections of the skin, hair and nails.

28 Sep 2026

Scientists uncover molecular mechanism that tunes eye light sensitivity

Weill Cornell Medicine investigators have determined the mechanism by which a molecule within cells can help tune the light sensitivity of the eyes.

24 Sep 2026

NSF awards $19 million to build 3D biological observatory for revealing life's smallest structures

How does learning change the wiring of your brain? How does a shark's eye make sense of its underwater world? How does a single-celled parasite cross the barrier that protects the brain? What might neurodegeneration look like at ultra-magnified scale?

24 Sep 2026