Electron Microscopy News and Research

RSS

Scientists uncover molecular mechanism that tunes eye light sensitivity

Weill Cornell Medicine investigators have determined the mechanism by which a molecule within cells can help tune the light sensitivity of the eyes.

24 Sep 2026

NSF awards $19 million to build 3D biological observatory for revealing life's smallest structures

How does learning change the wiring of your brain? How does a shark's eye make sense of its underwater world? How does a single-celled parasite cross the barrier that protects the brain? What might neurodegeneration look like at ultra-magnified scale?

24 Sep 2026

Structural insights into synchronous calcium channel gating in muscle cells

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously.

24 Sep 2026

Scientists map a giant parasite machine to fight tropical diseases

A study conducted between the University of Liège and Rockefeller University reveals, with near-atomic precision, the three-dimensional structure and function of a gigantic molecular machine essential to the survival of trypanosomatid parasites, which cause serious diseases in humans, animals and plants.

23 Sep 2026

New 3D structure reveals how cancer-linked BRD4 protein binds to chromosomes

A new 3D-structure of a cancer-linked protein bound to its cellular partner reveals details of how the protein binds to chromosomes and could offer insights for future disease treatments.

15 Sep 2026

Cannabis-derived nanovesicles showed early antitumor potential in mice

Researchers developed a Cannabis sativa hairy root culture system that produced stable plant-derived nanovesicles capable of promoting dendritic cell maturation and activating T-cell responses through TLR2- and TLR4-associated signaling. Oral administration also restored selected immune responses in immunosuppressed mice and suppressed tumor growth in an E.G7 lymphoma model, providing preliminary evidence for their immunomodulatory and antitumor potential.

15 Sep 2026

New structural insights could improve treatments for neurological disorders

Metabotropic glutamate receptors, which are important but difficult drug targets, interact in surprisingly varied ways with their principal regulatory proteins, according to two new studies led by Weill Cornell Medicine investigators.

15 Sep 2026

New dendritic constrictions reveal hidden complexity in neuronal signaling

Neurons receive thousands of signals via tree-like extensions called dendrites. Until now, these dendrites were thought to be relatively smooth cables that conduct electrical signals to the cell body.

11 Sep 2026

Scientists discover tiny protein region that shapes tooth enamel

Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.

11 Sep 2026

Giant-nucleus cells form the foundation of early-stage cancer

Iron is an essential micronutrient, but excess iron can damage cells and increase cancer risk. While many cells die from iron-induced oxidative stress, a subset survives and may become cancerous.

11 Sep 2026

Rituximab alters T-cell metabolism in patients with nephrotic syndrome

Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.

10 Sep 2026

Review highlights solute carriers as targets for central nervous system disorders

Solute carriers (SLCs) are specialized transport proteins that control the movement of nutrients, ions and neurotransmitters across cell membranes and are essential for brain metabolism and neuronal communication.

10 Sep 2026

Scientists discover new mechanism for bacterial fosfomycin resistance

Bacteria can survive antibiotics in several ways, including by pumping the drugs out of their cells before they can take effect.

7 Sep 2026

Psilocybin protects sensory nerves from chemotherapy damage in preclinical study

In mouse models, prophylactic psilocybin prevented or reduced multiple features of chemotherapy-induced peripheral neuropathy, with cycle-matched dosing sustaining protection during repeated cisplatin exposure without measurably affecting tumor growth. Experiments in human-derived sensory neurons and ex vivo peripheral nerves linked the effect to 5-HT2A-dependent preservation of mitochondrial trafficking and local axonal energy supply, while a nonhallucinogenic 5-HT2A agonist reproduced protection against mechanical hypersensitivity.

6 Sep 2026

Scientists capture how bacteria build their protective antibiotic-resistant barriers

Gram-negative bacteria are responsible for causing several infections that are hard to treat, owing to their high resistance to antibiotics.

4 Sep 2026

Research reveals how natural enzymes transcribe expanded eight-letter genetic code

All known life on earth utilizes the same genetic alphabet, consisting of four letters. Now, researchers at University of California San Diego have demonstrated that one of biology's most essential enzymes can accurately read and transcribe an expanded, eight-letter genetic alphabet.

4 Sep 2026

New brain map shows how electric fish manage noise

The brain cells help an African fish decode electric signals to spot prey, scan its murky surroundings and communicate with its fellows.

2 Sep 2026

Faulty myelin-making brain cells may help drive cognitive decline with age

Researchers found that greater age-related cognitive decline was associated with more dysfunctional oligodendrocytes, reduced NRF2 expression, smaller myelinated axons, and abnormally thicker myelin in human white matter. Experiments in mice showed that deleting NRF2 specifically from oligodendrocytes reproduced key white matter abnormalities and reduced cognitive improvement over time, implicating this pathway in cognitive aging.

26 Aug 2026

Gut bacteria may send different biological signals in Parkinson’s disease

A new study from the University of Oulu suggests that gut bacteria may send different biological signals in Parkinson’s disease.

26 Aug 2026

Cryo-EM provides real-time glimpse of cellular machinery reading DNA inside living organisms

All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the molecules responsible for helping build proteins that keep organisms alive.

20 Aug 2026