Endocannabinoids News and Research

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Extreme long-distance running triggers major surge in body's cannabis-like molecules

A marathon, 100 kilometers or even 230 kilometers in one go: Anyone running such distances puts enormous strain on their body.

4 Sep 2026

Breastmilk from cannabis users showed differences, but cannabis may not be the whole story

A narrative review found that maternal cannabis use may be associated with differences in breastmilk fat, protein, lactose, and the immune factor secretory immunoglobulin A, but evidence comes primarily from only two human studies and remains limited and inconsistent. The authors stress that maternal diet, food security, socioeconomic circumstances, and other forms of adversity could confound these associations and should be incorporated into future research.

31 Aug 2026

Scientists discover how neutrophils travel to infection sites without damaging healthy tissue

UMass Chan Medical School scientist Beth McCormick, PhD, and her team collaborated with researchers at the University of Bath to discover how neutrophils, the body's most abundant type of white blood cells, travel to infection sites without damaging healthy tissue.

25 Aug 2026

Immune cell navigation breakthrough offers hope for better anti-inflammatory drugs

A scientific collaboration between the University of Bath (UK) and the UMass Chan Medical School (USA) have determined how a specific type of white blood cells, called neutrophils, move through the body.

31 Jul 2026

Onset of "the munchies" after cannabis use could offer clues to help people with appetite loss

The urgent onset of "the munchies" after cannabis use isn't imaginary – it's a cognitive response that occurs regardless of sex, age, weight or recent food consumption and could offer clues to help people struggling with appetite loss.

19 Feb 2026

Combination therapy improves cognition in Alzheimer’s models

In recent years, research into cannabis and its main psychoactive ingredient, Δ⁹-tetrahydrocannabinol (THC), has unearthed medical benefits including anti-inflammatory and neuroprotective properties.

28 Jan 2026

Study reveals how acetaminophen may actually relieve pain

A new study from Indiana University scientists may aid the pharmaceutical industry in better understanding a popular over-the-counter pain reliever: Tylenol.

16 May 2025

Hormones may offer new way to treat wrinkles and hair graying

Hormones may be leveraged to treat and prevent signs of aging such as wrinkles and hair graying, according to a new study published in the Endocrine Society journal Endocrine Reviews.

26 Feb 2025

Researchers uncover brain mechanisms that help overcome instinctive fears

Researchers at the Sainsbury Wellcome Centre (SWC) at UCL have unveiled the precise brain mechanisms that enable animals to overcome instinctive fears.

6 Feb 2025

Global cannabis boom brings unexpected cardiovascular risks to light

This review examines the cardiovascular risks associated with cannabis, revealing its potential to cause severe heart health issues and inform public policy.

27 Jan 2025

Targeting brain enzyme may offer new treatment for obesity

Endocannabinoids in the brain play a key role in food intake and energy use. Modulating the action of these molecules could help fight obesity, say researchers at Université de Montréal's affiliated hospital research center.

16 Dec 2024

Boosting endocannabinoids could reduce opioid addiction risk

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ability to relieve pain, according to Weill Cornell Medicine investigators working with researchers from The Center for Youth Mental Health at NewYork-Presbyterian.

2 Dec 2024

It's official! Men and women experience and manage pain differently

Researchers uncover sex-specific pain management mechanisms, revealing men rely on endogenous opioids while women use alternative pathways for pain relief.

21 Oct 2024

High linoleic acid intake during pregnancy may harm fetal growth and raise obesity risk

High maternal linoleic acid intake during pregnancy may impact fetal development and increase the risk of obesity and inflammation in offspring. However, more research is needed to fully understand these effects in humans.

10 Sep 2024

Study explores how cannabis use affects breast milk and lactation

Study reviews the impact of cannabis use during pregnancy and lactation, highlighting potential changes in breast milk composition and lactation due to cannabinoid effects.

3 Apr 2024

How does social adversity influence biomarkers of stress and inflammation in children?

A recent study assessed whether social adversity affected the biomarkers of inflammation and stress in children.

22 Jan 2024

Omega-3s in the spotlight: The impact of EPA and DHA on athlete health and performance

Research paper reviews the effects of omega-3 fatty acids, EPA, and DHA, on athletes, discussing their benefits in inflammation control, cognitive function, and muscle maintenance, and the need for further research to fully understand their impact. It also addresses the risks and optimal intake of these supplements, highlighting their potential to improve athletic performance and recovery with minimal adverse effects at recommended doses.

27 Nov 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

New genetic test reveals a person’s predisposition to happiness

Your happiness levels aren't only based on external events. Genome testing can reveal how happy and optimistic you are predisposed to be. A leading testing expert reveals how variations of a key gene, CNR1, may have a significant impact on your level of happiness.

15 Sep 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023