Erythropoietin News and Research

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Erythropoietin, or its alternative erythropoetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow.

Casdatifan demonstrates durable responses in advanced kidney cancer trial

A new multi-center clinical study is shedding light on a potential new approach for patients with advanced kidney cancer, offering measurable clinical responses alongside a clearer view into how the disease operates beneath the surface.

27 Jul 2026

Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles

Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during physical activity.

13 Jul 2026

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and TaiGen Biotechnology, a listed discovery-based and market-focused pharmaceutical company, as well as TaiGen Biopharmaceuticals, its wholly-owned Beijing subsidiary (both referred to as "TaiGen"), today announced an exclusive pipeline out-licensing collaboration.

12 Dec 2025

Erythropoietin fails to improve outcomes for newborns with hypoxic-ischemic encephalopathy

Erythropoietin, a treatment for newborns with critically low levels of oxygen or blood supply to the brain at birth, does not prevent death or disability, according to a new multinational study.

25 Apr 2025

Manipulating a master regulator prevents tumor growth in mice

A protein identified nearly 40 years ago for its ability to stimulate the production of red blood cells plays a surprising, critical role in dampening the immune system's response to cancer.

24 Apr 2025

Study identifies genetic changes in blood stem cells of frequent blood donors

Researchers at the Francis Crick Institute have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells.

11 Mar 2025

A new strategy for enhancing the production of protein-based drugs

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

15 Jan 2025

Scientists link proteins to Alzheimer’s through cutting-edge genetic method

Researchers have developed MR-SPI, a novel method integrated with AlphaFold3, to identify causal protein biomarkers and predict their 3D structural changes in Alzheimer’s disease. This breakthrough offers insights into disease mechanisms and potential therapeutic targets.

5 Dec 2024

Lipid metabolism plays a critical role in red blood cell recovery from acute anemia

Red blood cells are the most abundant cells in the body. It has long been known that when red blood cells break down or anemia occurs due to bleeding, the hormone erythropoietin (EPO) increases, leading to the proliferation of immature cells (erythroblasts) that eventually become red blood cells, thus restoring the red blood cell count.

20 Sep 2024

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia.

29 Jul 2024

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Researchers trace the 60-year evolution of lipid nanoparticles (LNPs) for nucleic acid delivery, highlighting their potential to revolutionize gene therapy with safer and more effective treatments.

10 Jul 2024

Researchers leverage machine-learning techniques to predict future risk of pressure injuries

Bedsores - also known as pressure injuries - are the fastest rising hospital-acquired condition, according to the U.S. Agency for Healthcare Research in Quality, and as a result have become the second most common reason for medical malpractice suits in the United States.

9 Apr 2024

New custom-designed proteins can efficiently reach intramembrane targets

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently reach these "intramembrane" targets.

13 Mar 2024

Erythropoietin News and Research

Casdatifan demonstrates durable responses in advanced kidney cancer trial

Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Erythropoietin fails to improve outcomes for newborns with hypoxic-ischemic encephalopathy

Manipulating a master regulator prevents tumor growth in mice

Study identifies genetic changes in blood stem cells of frequent blood donors

A new strategy for enhancing the production of protein-based drugs

Scientists link proteins to Alzheimer’s through cutting-edge genetic method

Lipid metabolism plays a critical role in red blood cell recovery from acute anemia

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Researchers leverage machine-learning techniques to predict future risk of pressure injuries

New custom-designed proteins can efficiently reach intramembrane targets

Using near-infrared spectroscopy to study how infant brains respond to touch

New implantable device carries insulin-producing islet cells to control diabetes

Riboswitch may be the key to advance gene therapy, regenerative medicine

Circulating microparticle proteins predict placenta accreta spectrum before delivery

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Adding erythropoietin to cooling therapy shows no added benefits for newborns with birth asphyxia

New regulatory code of protein glycosylation

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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