Fluoroquinolone News and Research

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Fluoroquinolone is a type of drug used to prevent and treat infections. Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture. This risk is further increased in those over age 60, in kidney, heart, and lung transplant recipients, and with use of concomitant steroid therapy.

How do common painkillers drive stronger E. coli resistance?

Research shows that non-antibiotic medications like ibuprofen can enhance E. coli mutations, raising concerns about antimicrobial resistance in older adults.

29 Aug 2025

Study shows probiotics help preterm babies fight antibiotic-resistant bacteria

Researchers found that probiotics help reduce antibiotic-resistant bacteria in the guts of very-low-birth-weight preterm infants, but cannot fully prevent resistance genes from spreading. Antibiotic use still promotes gene swapping, highlighting the limits of probiotics alone in neonatal care.

17 Aug 2025

endTB-Q trial highlights importance of individualized regimens

Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs while others may warrant more aggressive therapy, according to the findings of a new study led by an international group of researchers including scientists from Harvard Medical School and conducted across six countries in Asia, Africa, and South America.

17 Jul 2025

TMP-SMX in early pregnancy increases risk of birth defects, new study shows

A large US cohort study found that using trimethoprim-sulfamethoxazole (TMP-SMX) for UTI in the first trimester of pregnancy was associated with a higher risk of congenital malformations compared to β-lactam antibiotics. No increased risk was seen with nitrofurantoin or fluoroquinolones.

10 Jul 2025

Maternal exposure to metals rewires infants’ gut and resistance genes

Prenatal exposure to trace elements like selenium, copper, and arsenic can significantly alter the infant gut microbiome, metabolism, and antibiotic resistance gene patterns. These changes appear as early as three months and evolve during the first year of life.

5 Jun 2025

Global analysis of antimicrobial resistance in Campylobacter

Announcing a new article publication for Zoonoses journal. The zoonotic pathogen Campylobacter is a major foodborne bacterial species worldwide. The distribution and drivers of antimicrobial resistance (AMR) in global Campylobacter strains remain largely unknown. Therefore, a comprehensive analysis of longitudinal trends and driving factors of AMR in Campylobacter is necessary at a global level.

26 Mar 2025

Three new drug regimens offer hope for drug-resistant tuberculosis

Tuberculosis remains one of the top infectious disease killers worldwide, a challenge amplified by drug-resistant forms of the disease.

29 Jan 2025

Study projects global antibiotic use to rise by over 50% by 2030

A study reveals a 20.9% rise in global antibiotic use from 2016 to 2023, with middle-income countries leading the increase and highlighting resistance issues.

21 Nov 2024

New small molecule offers hope in combating antibiotic resistance

Researchers from the University of Oxford have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.

24 May 2024

WHO updates Bacterial Priority Pathogens List to combat antimicrobial resistance

The World Health Organization (WHO) today released its updated Bacterial Priority Pathogens List (BPPL) 2024, featuring 15 families of antibiotic-resistant bacteria grouped into critical, high and medium categories for prioritization.

20 May 2024

Study reveals high levels of antibiotic resistance in meat sold for consumption

New research presented at the ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) has found substantial levels of resistance to critically important antibiotics in meat sold for human and animal consumption.

28 Apr 2024

Rising antimicrobial resistance in STIs: A call for global action

Review delves into the rising challenge of antimicrobial resistance in sexually transmitted infections, underscoring the need for innovative treatments and the critical role of global surveillance in managing diseases like gonorrhea and syphilis.

21 Mar 2024

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

20 Dec 2023

Breakthrough in tuberculosis treatment: TB-PRACTECAL trial reveals efficacy of new oral regimen

The TB-PRACTECAL clinical trial outcomes, which evaluated the efficacy and safety of oral bedaquiline.

20 Nov 2023

Does your gut microbiome play a role in therapeutic outcomes?

The role of the gut microbiome and its metabolites in altering the therapeutic outcomes

12 Oct 2023

The relationship between the burden of antibiotic resistance in humans and community access to drinking water and sanitation

Researchers determined the link between improved access to sanitation and better water quality and the human intestines' antibiotic resistance gene frequency.

5 Jul 2023

Beyond expectations: study finds treatment success gap in drug-resistant Tuberculosis

Researchers performed a review of global treatment outcomes of drug-resistant Tuberculosis.

27 Jun 2023

Rapid spread of antibiotic-resistant E. coli across Europe raises concerns

Research paper highlights the swift cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area from 2012 to June 2022. The findings emphasize the need for continued surveillance and effective measures to combat the spread of antibiotic-resistant bacteria.

15 May 2023

Study reveals alarming global burden of antimicrobial resistance in bacterial infections

The paper presents a systematic analysis of the global burden of bacterial antimicrobial resistance in 2019. The authors highlight the urgent need for action to address this growing public health threat.

23 Apr 2023

Antibiotic-resistant strains of typhoid bacteria continue to spread out of South Asia

Antibiotic-resistant strains of Salmonella Typhi, the typhoid bacteria, have spread from South Asia to other countries nearly 200 times since 1990, new research suggests.

29 Jun 2022