Frontotemporal Dementia (FTD) News and Research

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FAU researchers create deep learning model that detects and evaluates Alzheimer's, FTD

Dementia is a group of disorders that gradually impair memory, thinking and daily functioning. Alzheimer's disease (AD), the most common form of dementia, affects about 7.2 million Americans aged 65 and older in 2025.

15 Dec 2025

New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples

Researchers have developed a new tool, FibrilPaint combined with the FibrilRuler test, that allows scientists to directly measure the length of toxic Tau amyloid fibrils in tiny fluid samples, from the earliest aggregation stages to mature fibrils and even at very low concentrations.

11 Dec 2025

Protein tied to ALS and dementia plays a role in regulating DNA mismatch repair

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA mismatch repair, a process essential for replicating genetic information and cell health.

2 Dec 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

UCSF receives historic $100 million gift for Memory and Aging Center

UC San Francisco today announced a $100 million gift to its renowned Memory and Aging Center (MAC). It is the first gift to name a UCSF division, which will now be the Edward and Pearl Fein Memory and Aging Center.

29 Oct 2025

APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s

Researchers discovered that people carrying the APOE ε4 gene variant share a unique immune-related protein signature across their blood, brain, and cerebrospinal fluid—regardless of neurodegenerative disease diagnosis. This signature reveals a fundamental, disease-independent vulnerability linked to APOE ε4, reframing our understanding of genetic risk in conditions like Alzheimer's, Parkinson’s, ALS, and FTD.

21 Jul 2025

Glycogen metabolism in neurons emerges as key to fighting Alzheimer's

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

1 Jul 2025

Epileptic seizures more common in frontotemporal dementia patients than previously known

According to a recent study, in patients with frontotemporal dementia (FTD), epileptic seizures are significantly more common than previously known.

2 Jun 2025

Stress granules play a protective role against neurodegenerative disease

Scientists from St. Jude Children's Research Hospital and Washington University in St. Louis report mechanistic insights into the role of biomolecular condensation in the development of neurodegenerative disease.

28 May 2025

Study offers new clues to early detection of frontotemporal dementia in middle age

Dementia usually affects older people, so when it occurs in middle age, it can be hard to recognize. The most common form is frontotemporal dementia (FTD), which is often mistaken for depression, schizophrenia, or Parkinson's disease before the correct diagnosis is reached.

16 May 2025

New approach may prevent neurotoxic protein aggregates in ALS

Researchers at Goethe University, Johannes Gutenberg University Mainz and Kiel University discover possible method for preventing protein aggregates – Cluster4Future PROXIDRUGS research project.

23 Apr 2025

New scientific clue could unlock key cellular pathway leading to neurodegenerative diseases

In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer's disease, and the progressive damage to the brain's frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).

14 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Promising ultrasound therapy for Alzheimer's disease licensed to new start-up

A promising ultrasound therapy to potentially restore brain function in people with Alzheimer's disease has been licenced to a new start-up spun out of The University of Queensland.

16 Dec 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

C-Path announces important leadership appointments in neurology and Alzheimer's research

Critical Path Institute (C-Path) today announced key leadership appointments: Diane Stephenson, Ph.D., has been promoted to Vice President of Neurology, and Nadine Tatton, Ph.D., has been welcomed as the new Executive Director of C-Path's Critical Path for Alzheimer's Disease (CPAD) Consortium.

7 Nov 2024

Frontotemporal Dementia (FTD) News and Research

FAU researchers create deep learning model that detects and evaluates Alzheimer's, FTD

New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples

Protein tied to ALS and dementia plays a role in regulating DNA mismatch repair

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

UCSF receives historic $100 million gift for Memory and Aging Center

APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s

Glycogen metabolism in neurons emerges as key to fighting Alzheimer's

Epileptic seizures more common in frontotemporal dementia patients than previously known

Stress granules play a protective role against neurodegenerative disease

Study offers new clues to early detection of frontotemporal dementia in middle age

New approach may prevent neurotoxic protein aggregates in ALS

New scientific clue could unlock key cellular pathway leading to neurodegenerative diseases

Stress granules as potential biomarkers for neurodegenerative diseases

Promising ultrasound therapy for Alzheimer's disease licensed to new start-up

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

C-Path announces important leadership appointments in neurology and Alzheimer's research

Study reveals shared and unique molecular markers across multiple forms of dementia

Does air pollution drive dementia?

Acute kidney injury doubles dementia risk, study finds

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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