Glucose Metabolism News and Research

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Study links protein interaction to senescent cell survival

Senescent cells - cells that have stopped dividing but remain metabolically active - can accumulate with age and contribute to chronic inflammation and tissue dysfunction

1 Sep 2026

Artificial sweetener xylitol associated with higher risk of adverse cardiovascular events

A study to be presented at ESC Congress 2026 will show that high blood levels of the artificial sweetener, xylitol, were associated with increased risk of major adverse cardiovascular events.

26 Aug 2026

What decades of wine research can, and cannot, tell us about health

A narrative review found that moderate wine intake has repeatedly been associated with lower all-cause and cardiovascular mortality, with proposed mechanisms involving ethanol and grape-derived polyphenols, but the evidence remains largely observational and cannot establish causation. The authors argue that drinking pattern, beverage type, age, cancer risk, and risk-modeling choices all influence how the J-shaped association should be interpreted and how alcohol guidelines are developed.

25 Aug 2026

Study provides a more nuanced picture of biological mechanisms linked to autism

How does autism manifest in the brain? Researchers from the University of Southern Denmark and Odense University Hospital have investigated this question in a new study involving 60 adults.

21 Aug 2026

Sprinters and non-athletes had similar gut diversity, but one key difference emerged

College sprint athletes showed a distinct gut microbial community structure, including higher abundance of Segatella copri and Bifidobacterium adolescentis, compared with non-athletic students. Their microbiomes also showed predicted enrichment of carbohydrate and amino acid metabolism pathways, while exploratory analyses linked several dietary factors with the signature bacteria.

20 Aug 2026

Whole grains, legumes and vegetables stand out in a major review of diabetes diets

Healthy plant-based diets rich in whole grains, legumes, fruits, vegetables, nuts, and seeds are associated with better glycemic control and a lower risk of type 2 diabetes. The review finds that food quality and processing matter more than simply avoiding animal foods, while unhealthy plant-based patterns and higher red and processed meat intake are associated with greater metabolic risk.

18 Aug 2026

Your social life may leave a mark on how fast you age

Positive social experiences were associated with longer survival, while childhood adversity predicted shorter survival in a 1,309-person longitudinal cohort followed for nearly 15 years. Epigenetic aging, particularly GrimAge2, emerged as the strongest potential pathway linking social experiences with mortality risk.

12 Aug 2026

Thinning cancer cells' sugar coating could expose tumors to immune attack

Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat of sugar-derived molecules that throws the proverbial hounds of our immune systems off the scent.

7 Aug 2026

Type 2 diabetes linked to more severe menopause symptoms

The type of menopause symptoms, as well as their severity, can differ greatly among women. A number of earlier studies have suggested various reasons for those differences.

5 Aug 2026

Daily tomatoes lowered a key marker of liver fat in MASLD trial

An exploratory randomized trial found that 200 g of raw tomatoes plus 50 g of tomato sauce daily for six weeks produced a greater reduction in CAP-defined hepatic steatosis than a tomato-free diet in adults with MASLD. The improvement occurred without major weight or metabolic changes, but larger and longer trials are needed to confirm its clinical significance.

2 Aug 2026

Heatwave exposure associated with accelerated biological aging in middle-aged and older adults

As global climate change intensifies, heatwaves are becoming more frequent, longer, and more severe, emerging as an important environmental stressor for human health.

28 Jul 2026

Moderate coffee intake may support heart health, AHA says

The American Heart Association finds that habitual coffee consumption is associated with lower risks of several cardiovascular outcomes, although most evidence comes from observational studies. Moderate intake is generally safe for most adults, while energy drinks and individual caffeine sensitivity may increase cardiovascular concerns.

21 Jul 2026

Evening chronotype links later eating with higher body fat

Research shows evening chronotypes in women consume more energy later, leading to higher body fat and metabolic issues, highlighting chrono-nutrition's role.

16 Jul 2026

Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles

Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during physical activity.

13 Jul 2026

Breaking up long periods of sitting is linked to lower cancer risk

The study highlights that how sedentary time is accumulated affects cancer risk, with prolonged sitting linked to higher risk and activity offering protection.

7 Jul 2026

Reversing macrophage metabolism may improve cancer immunotherapy outcomes

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment.

1 Jul 2026

Simple blood test could identify the most effective obesity drug

Fasting blood tests measuring GLP-1 and GIP levels may predict obesity treatment response to semaglutide and tirzepatide, enhancing personalized therapy.

29 Jun 2026

Longer hormone exposure linked to healthier brain aging in women

Research indicates that hormonal therapies and later menopause are associated with increased brain volume and thickness, promoting healthier aging.

26 Jun 2026

Gut microbes may help explain why obesity and type 2 diabetes become harder to reverse

This review describes how gut microbial messengers, including SCFAs, microbiota-modified bile acids, neuroactive metabolites, and extracellular vesicles, may shape obesity and type 2 diabetes through the microbiota-gut-brain axis.

17 Jun 2026

Glucosamine may worsen Alzheimer’s by fueling abnormal brain glycosylation

A Nature Metabolism study identifies brain hyperglycosylation as a metabolic driver of Alzheimer’s disease, with increased N-glycan biosynthesis seen in human AD tissue and mouse models. Reducing glycosylation improved memory in AD mice, while glucosamine worsened memory deficits in 5xFAD mice and was associated with poorer outcomes in dementia patients.

14 Jun 2026