Glutamine News and Research

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Glutamine is an amino acid used in nutrition therapy. It is also being studied for the treatment of diarrhea caused by radiation therapy to the pelvis.

Review highlights how altered metabolism drives kidney cancer growth

Clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer, is increasingly understood as a malignancy shaped by profound changes in cellular metabolism.

24 Sep 2026

New discovery paves way for highly personalized breast cancer therapies

MYC is a common oncogene that regulates tumor growth and spread, yet no approved drugs exist to target it.

28 Aug 2026

Reversing macrophage metabolism may improve cancer immunotherapy outcomes

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment.

1 Jul 2026

Targeting metabolic pathways could prevent relapse in KRAS-mutant cancers

Our cells rely on tightly regulated signaling pathways to control when they grow, divide, and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous.

25 Jun 2026

New review highlights how glutamine metabolism shapes the complex tumor microenvironment

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progression and therapeutic response

25 May 2026

Engineered gut bacteria successfully treat metabolic drivers of liver disease

When the liver fails, toxins - such as ammonia - that should be filtered from the blood build up and reach the brain.

28 Apr 2026

Targeting glutamine metabolism enhances CAR-macrophage cancer therapy

Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function.

20 Apr 2026

Gut-derived blood markers may help predict who develops coronary heart disease

Researchers used five prospective cohorts from the US and China to identify circulating gut microbiota-related metabolites linked to future coronary heart disease, then tested the findings through discovery, in silico validation, and targeted quantitative validation. The study ultimately highlighted nine metabolites associated with incident CHD, supporting a potential role for microbial metabolism in heart disease risk while not proving causation

18 Mar 2026

Targeting glutamine metabolism offers new hope for synovial sarcoma treatment

Synovial sarcoma is an aggressive malignant tumor that primarily affects the limbs of teenagers and young adults.

26 Feb 2026

New 3D liver reconstructions show how cirrhosis reshapes organ architecture

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians capture the spatial microstructure of multiple lobes of this multitasking organ.

23 Feb 2026

Study explores how reversible RNA editing could transform future cardiovascular medicine

This mini-review synthesises evidence showing that adenosine-to-inosine RNA editing plays an important regulatory role in cardiovascular development, cellular homeostasis, and disease biology. It highlights emerging links between dysregulated RNA editing and cardiovascular conditions while outlining biomarker potential and reversible RNA-editing therapeutic strategies that remain under investigation.

15 Feb 2026

Study elucidates key steps in the ubiquitin tagging of mutated huntingtin protein

Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future therapies.

5 Feb 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

BATF2: A novel tumor suppressor silenced by glutamine in head and neck cancer

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to researchers from The University of Texas MD Anderson Cancer Center.

7 Jan 2026

Immune cell energy metabolism shapes the progression of atherosclerosis

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis - and how this knowledge could lead to better diagnostics and future therapies.

30 Dec 2025

Study shows glial cells actively shape addictive responses to nicotine

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult.

4 Dec 2025

AI model ranks genetic variants from severe to mild disease mutations

popEVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant scoring for rare diseases.

3 Dec 2025

Plant-based oat protein hybrid doubles iron absorption in women

Research on oat protein nanofibril-iron hybrids highlights their potential to significantly improve iron absorption, tackling global nutritional deficiencies.

12 Nov 2025

New drug combination shows promise in treating colorectal cancer

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

22 Oct 2025

Scientists discover why a powerful leukemia drug fails in most patients

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients – and found a potential way to overcome that resistance.

17 Oct 2025