Hand Foot and Mouth Disease News and Research

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Hand-foot-mouth disease is an infectious disease caused by a virus and it often affects the throat first.

Not serious enough to turn on the siren, toddler’s 39-mile ambulance ride still cost over $9,000

Elisabeth Yoder's son, Darragh, was 15 months old in August when he developed what at first looked to his parents like hand, foot, and mouth disease.

25 Nov 2025

New AI approach speeds up antiviral discovery for human enterovirus 71

Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.

6 May 2025

Machine learning uncovers promising drug leads against human enterovirus 71

Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.

29 Apr 2025

Study reveals impact of climate change on enterovirus outbreaks

Outbreaks of hand, foot and mouth disease (HFMD), which causes fever and rash in young children, typically occur in the summer months.

6 Aug 2024

Study demonstrates prolonged persistence of enteroviruses on commonly encountered surfaces

Hand, foot, and mouth disease (HFMD) is a contagious disease that mainly affects young children in the Asia-Pacific region.

23 Nov 2023

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Peruvoside, a plant-based compound that is commonly used to treat heart failure, has been discovered to be able to prevent up to 12 medically important viruses, all originating from different virus families.

22 Jun 2023

False positive monkeypox tests in low-risk patients with no exposures

Researchers reported three monkeypox diagnoses presenting atypical rashes.

13 Sep 2022

Hand, foot and mouth disease afflicting children hyped up as 'tomato flu'

Leading clinicians and medical researchers in India say they are aghast at the media reports that portray hand, foot and mouth disease (HFMD) — a common, relatively mild, viral infection afflicting children — as caused by a new virus responsible for what is dubbed as 'tomato flu'.

5 Sep 2022

Complex RNA structures could have untapped therapeutic potential in the fight against COVID-19

To the untrained eye, the loops, kinks and folds in the single strand of RNA that makes up the coronavirus genome look like a jumble of spaghetti or tangled yarn. But to researchers like Amanda Hargrove, a chemistry professor at Duke University, the complex shapes that RNA takes on as it folds upon itself could have untapped therapeutic potential in the fight against COVID-19.

26 Nov 2021

Enterovirus 71 vaccine candidate strains exhibit good immunogenicity and cross-neutralization activity

Announcing a new article publication for Zoonoses journal. In this commentary researchers from Beijing Minhai Biotechnology Co., Ltd., Beijing, China, Hubei Provincial Center for Disease Control and Prevention, Wuhan, China, Guangdong Provincial Institute of Biological Products and Drugs, Guangzhou, China, Gaozhou Center for Disease Control and Prevention, Guangdong, China and the Yangchun Center for Disease Control and Prevention, Guangdong, China consider immungenicity and cross-neutralizing activity of enterovirus 71 vaccine candidate strains.

27 Sep 2021

Novel broad-spectrum antiviral compounds effective against Zika and SARS-CoV-2

A research team at the University of Alberta, Canada, led by Dr. Daniel Limonta, has described two novel molecules with broad antiviral properties that are effective against a range of virus types, including SARS-CoV-2.

21 May 2021

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

Researchers report on a Chicken-derived antibody against SARS-CoV-2, offering preliminary data on a potential therapeutic for COVID-19 warranting further research.

19 Feb 2021

Study finds surprising defensive functions of the immune system against new viral attacks

Scientists are opening new windows into understanding more about the constantly shifting evolutionary arms race between viruses and the hosts they seek to infect.

29 Jan 2021

Researchers uncover the role of protein in identifying common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

1 Dec 2020

Early interferon therapy may mitigate COVID-19 severity

A recent review of COVID-19 therapies explores the utility of interferons in the battle against severe COVID-19, and concludes that they deserve further development.

26 Nov 2020

Researchers identify acrylamides that inhibit SARS-CoV-2 main protease

A new study in the preprint server bioRxiv published in November 2020 describes the discovery of acrylamide fragments that can effectively disable key enzymes in both the hand, foot and mouth virus and SARS-CoV-2 virus.

11 Nov 2020

Researchers identify a potential drug candidate for hand, foot and mouth disease

A study appearing next week in the journal Nature Communications offers some good news in the search for antiviral drugs for hard-to-treat diseases. Researchers have identified a potential new drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children

22 Sep 2020

New Vietnamese enterovirus C4 strains possibly more virulent than B5 strains

A new study published in January 2020 in the journal Scientific Reports reports the presence of a new lineage of enterovirus responsible for the hand-foot-and-mouth disease (HFMD). They think this could be more virulent than the earlier B5 subtype.

12 Apr 2020

Deaths of Chinese children, adolescents from infectious diseases prior to COVID-19 found to be rare

Deaths of children and adolescents in China due to infectious diseases were becoming rare prior to the COVID-19 pandemic, according to a new study.

3 Apr 2020

Video images offer real-time view into the kinetics of viral assembly

For the first time, researchers have captured images of the formation of individual viruses, offering a real-time view into the kinetics of viral assembly. The research provides new insights into how to fight viruses and engineer self-assembling particles.

4 Oct 2019