Hemochromatosis News and Research

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Hemochromatosis is the most common form of iron overload disease. Primary hemochromatosis, also called hereditary hemochromatosis, is an inherited disease. Secondary hemochromatosis is caused by anemia, alcoholism, and other disorders.

Ion channel TPC1 identified as key regulator of iron homeostasis

Researchers have deciphered the role of an ion channel in iron homeostasis, opening up new possibilities for treating iron metabolism disorders.

6 Aug 2026

Osteoporosis drugs show promise against toxic iron accumulation

Researchers at the University of São Paulo (USP) in Brazil have discovered that two osteoporosis drugs (etidronate and tiludronate) may combat diseases caused by iron accumulation in the body.

23 Feb 2026

EULAR develops first classification criteria for hemochromatosis arthropathy

EULAR - The European Alliance of Associations for Rheumatology - has developed the first classification criteria for hemochromatosis arthropathy (HA) from a unique derivation cohort using rigorous methodology.

5 Nov 2025

Pain clinic CEO faced 20 years for making patients ‘human pin cushions.’ He got 18 months.

Federal prosecutors sought a maximum prison sentence of nearly 20 years for the CEO of Pain MD, a company found to have given hundreds of thousands of questionable injections to patients, many reliant on opioids.

15 May 2025

How blood iron levels shape the pace of biological aging

Researchers examine the role of blood iron levels in DNA methylation-based measurements of biological aging.

29 Apr 2025

Engineered fat cells starve tumors and prevent cancer growth

Scientists transformed energy-storing white fat cells into calorie-burning 'beige' fat. Once implanted, they outcompeted tumors for resources, beating back five different types of cancer in lab experiments.

4 Feb 2025

New research explores hidden health risks of hereditary hemochromatosis

A study links undetected diabetes in hemochromatosis patients to increased mortality, highlighting the need for early detection and revised clinical guidelines.

11 Dec 2024

Regulating iron overload: Liraglutide's potential benefits

Researchers assess the role of liraglutide in regulating iron metabolism in a mouse model of hereditary hemochromatosis.

30 Sep 2024

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia.

29 Jul 2024

Differing definitions of iron deficiency lead to divergent estimates of prevalence, study finds

How different ways of defining iron deficiency (ID) impact the prevalence estimates of this common disorder among women.

12 Jun 2024

USC study unveils iron as key driver of lung inflammation in allergic asthma

New USC research shows that iron serves as a gas pedal driving certain immune cells that cause inflammation in the lungs during an allergic asthma attack – and blocking or limiting iron may reduce the severity of symptoms.

8 May 2024

Renewed classification of primary iron overload syndromes based on Hep25/FP system

The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes (PIOSs).

29 Apr 2024

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Genomic screening to identify hemochromatosis - a disorder that causes iron levels in the body to rise to dangerous levels - encourages people with the condition to seek treatment and ongoing management, a Geisinger study found.

26 Oct 2023

Gene mutation responsible for hereditary hemochromatosis may be a risk factor for movement disorders

A disorder called hereditary hemochromatosis, caused by a gene mutation, results in the body absorbing too much iron, leading to tissue damage and conditions like liver disease, heart problems and diabetes.

1 Aug 2022

Molecular autopsy of dried blood spots can identify underlying cause of sudden cardiac death in a young person

The underlying cause of sudden cardiac death (SCD) in a young person is often difficult to identify. A genetic analysis could provide more information in many cases, but blood samples are not collected routinely at the time of death, and DNA extracted from the tissues collected at autopsy is damaged because of the way they are fixed in formalin and paraffin-embedded.

30 Aug 2021

UCLA professor honored for contributions to the field of hematology

Dr. Elizabeta Nemeth, professor of medicine and director of the Center for Iron Disorders at the David Geffen School of Medicine at UCLA, has been awarded the 2021 William Dameshek Prize by the American Society of Hematology (ASH) for her contributions to the field of hematology.

2 Jul 2021

Genetic variation that regulates iron metabolism may enhance endurance performance in athletes

A genetic variation that regulates iron metabolism may enhance athletes' endurance performance, researchers at the University of Toronto have shown.

24 Mar 2021

Novel nanoscale bio-probe could detect iron disorders

Chronic iron imbalances - having either too little or too much iron in the blood - can result in medical conditions ranging from anemia and hemochromatosis through to more severe diseases, such as cancer, Parkinson's Disease and Alzheimer's Disease.

29 Apr 2020

Iron overload, variant gene and malaria resistance linked in African study

A new study shows that a rare genetic mutation giving rise to a variant of the TP53 gene called P47S causes several linked biological processes.

24 Jan 2020

AMP announces recipients of 2019's Award for Excellence in Molecular Diagnostics

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostics professional society, today announced the recipients of this year's Award for Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership Award and Meritorious Service Award.

19 Sep 2019