Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Evidence remains insufficient to support routine use of lumbar braces for chronic low back pain

A new Cochrane review finds very low-quality evidence on lumbar supports for chronic low back pain, meaning that no strong recommendations can be made either for or against their use.

1 Sep 2026

ANESTHESIOLOGY 2026 to highlight latest advances in anesthesia care

Ketamine given during C-sections could help ease early symptoms of postpartum depression. Common pain relievers, such as ibuprofen, may reduce the risk of delirium after surgery.

11 Aug 2026

Lung tumors hack the nervous system to cause severe cachexia

Cachexia is a condition in which patients affected by cancer or other chronic diseases become sick and lose weight.

9 Jul 2026

Can ibuprofen improve drug-resistant tuberculosis treatment?

While ibuprofen reduced inflammatory markers in drug-resistant TB patients, it did not enhance treatment outcomes, indicating the need for further research.

3 Jul 2026

Lung tumors hijack nervous system to drive cancer-related cachexia

According to the Cleveland Clinic, a quarter of cancer deaths can be attributed to one source: cachexia. Cachexia is a syndrome that accompanies underlying chronic illness and causes unwanted muscle and fat loss, reducing quality of life and sometimes even limiting treatment options.

2 Jul 2026

New research reassures mothers on NSAID safety during the first trimester

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, taken during the first trimester of pregnancy are not associated with an increased risk of major birth defects, according to a new study published May 14th in the open-access journal PLOS Medicine by Sharon Daniel of Ben-Gurion University of the Negev and Clalit Health Services, Beer-Sheva, Israel, and colleagues.

15 May 2026

Can exercise or ibuprofen fight chemo brain?

This study suggests exercise can mitigate cancer-related cognitive impairment, but combining it with ibuprofen offers no additional cognitive benefits.

23 Apr 2026

Ibuprofen shown to improve cognitive function in patients undergoing chemotherapy

Researchers have already shown that mild to moderate exercise can reduce "chemo brain," and a new study suggests that a low dose of an over-the-counter anti-inflammatory, ibuprofen, can also achieve positive results for cancer patients.

21 Apr 2026

Exercise and ibuprofen help reduce cognitive impairment during chemotherapy

Up to 80% of people who receive chemotherapy experience cancer-related cognitive impairment, which most commonly involves mild-to-moderate changes such as difficulty paying attention, memory lapses, and struggles with multitasking.

20 Apr 2026

Drug-releasing stitches aim to reduce inflammation and improve healing

Deep cuts from accidents or surgeries require stitches, typically followed by oral anti-inflammatory medications like ibuprofen. While these medications help with pain, they don't act specifically on the wounds.

24 Mar 2026

Daily aspirin not reliable for preventing bowel cancer

Daily aspirin use does not offer a quick or reliable way to prevent bowel cancer in the general population and carries immediate risks of serious bleeding, a new Cochrane review finds.

25 Feb 2026

Solvent-free method improves drug solubility using mesoporous silica

A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water.

31 Jan 2026

The role of school health services in adolescent wellness

She has written a doctoral thesis on health-related quality of life among children and young people in Agder.

30 Jan 2026

Study finds no safety or efficacy gap between paracetamol and ibuprofen for neonatal PDA

In a UK pilot randomized trial, intravenous paracetamol and ibuprofen showed no statistically significant differences in short-term efficacy or safety when used as rescue therapy for hemodynamically significant patent ductus arteriosus in very preterm infants. The study demonstrated high feasibility but was not powered to determine clinical superiority or equivalence between treatments.

21 Jan 2026

Evidence shows no autism risk from paracetamol in pregnancy

Evidence from a comprehensive review shows no link between paracetamol in pregnancy and neurodevelopmental issues, supporting its safe use for pain management.

21 Jan 2026

THC products provide small improvements in pain but carry side effects

A new systematic evidence review finds that cannabis products that carry relatively high levels of the psychoactive compound tetrahydrocannabinol, commonly known as THC, may provide short-term improvements in pain and function.

22 Dec 2025

Blood test identifies colon cancer patients who benefit from anti-inflammatory medication

A blood test could help doctors decide which patients with colon cancer should receive anti-inflammatory medication along with chemotherapy after surgery, according to new study in JAMA Oncology.

15 Dec 2025

TikTok videos about gout often contain misleading information

A new paper in Rheumatology Advances in Practice, published by Oxford University Press, indicates that TikTok videos about gout are commonly misleading, inconsistent, or inaccurate.

11 Dec 2025

Fever-resistant bird flu viruses pose a significant threat to humans

Bird flu viruses are a particular threat to humans because they can replicate at temperatures higher than a typical fever, one of the body's ways of stopping viruses in their tracks, according to new research led by the universities of Cambridge and Glasgow.

28 Nov 2025

Chronic pain in adults linked to increased risk of developing high blood pressure

Chronic pain in adults may increase their risk of high blood pressure, and the location and extent of pain and if they also had depression were contributing factors, according to new research published today in Hypertension, an American Heart Association journal.

17 Nov 2025