Liquid Chromatography Mass Spectrometry (LC MS) News and Research

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Why protein powders can secretly cause doping bans

Adulterated protein supplements can lead to unintentional doping. This review outlines detection strategies and protective measures for athletes and clinicians.

9 Oct 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Synthetic Psychedelics: A Growing Public Health Concern

In this interview, Jonathan Ferguson discusses how knowledge of an emerging public health concern identified at Pittcon 2024 has evolved a year on.

From Pittcon 26 Aug 2025

Study shows promising anti-diabetic potential of coffee's functional components

Three of the compounds demonstrated significant inhibitory effects on α-glucosidase, a key enzyme in carbohydrate digestion. The findings could pave the way for new functional food ingredients targeting type 2 diabetes.

18 Aug 2025

Why Mānuka isn't the only healing honey from New Zealand anymore

New research from Auckland University of Technology reveals that eight native New Zealand honeys, beyond mānuka, possess unique antioxidant, antibacterial, and bioactive properties. Thyme and beech honeydew stood out for their vitamin C and polyphenol content.

25 Mar 2025

Breastfeeding after COVID-19 vaccination is safe, with minimal changes to milk composition

This study reveals how SARS-CoV-2 infection significantly alters human milk composition, while COVID-19 vaccination causes minimal, transient changes, underscoring the safety of breastfeeding during vaccination.

19 Dec 2024

Liver conversion of fructose fuels cancer growth by supplying lipids for tumor proliferation

This research highlights the indirect role of fructose in cancer, revealing how liver metabolism enhances tumor growth through lipid-mediated mechanisms.

5 Dec 2024

Gut transit time and pH shape microbiome individuality and dietary responses

Scientists reveal gut transit time and pH as key drivers of microbiome and metabolic individuality, paving the way for personalized dietary strategies.

1 Dec 2024

Fermented kimchi may help combat obesity by regulating gut microbiota

Kimchi consumption significantly reduces body fat and enhances metabolic indicators in overweight individuals, highlighting its role in obesity management.

22 Nov 2024

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option in combination with temozolomide.

21 Nov 2024

Sapio Sciences Collaborates with Waters Corporation to Improve Efficiency of Laboratory Operations

The advanced connectivity of Sapio LIMS with waters_connect for Quantitation liquid chromatography mass spectrometry (LC-MS) software.

From Sapio Sciences 18 Nov 2024

Key reason why some cancers do not respond to immunotherapy identified

Research reveals SLC13A3's role in tumor cell survival and immune therapy resistance, highlighting its potential as a target for improved cancer treatments.

12 Nov 2024

P-stalk ribosomes identified as key regulators of immune evasion in cancer

Research uncovers how P-stalk ribosomes regulate cytokine responses, driving immune evasion in tumors across multiple cancer types. It offers new insights into post-translational mechanisms influencing immunotherapy success.

23 Oct 2024

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Researchers identify distinct gut microbiome metabolites in women with endometriosis, offering potential for non-invasive diagnosis and new therapies.

14 Oct 2024

Early lifestyle changes lead to lasting impacts on metabolism

A new study from the University of Eastern Finland (UEF) uncovers how early lifestyle changes can have long-lasting impacts.

12 Sep 2024

Is semaglutide use during breastfeeding safe?

Researchers found no detectable levels of semaglutide in breast milk, suggesting minimal risk to breastfed infants, but highlighted the need for monitoring maternal nutrition and milk production.

2 Sep 2024

Study investigates the link between an exposome score and metabolic health across childhood

The combined effect of environmental exposures and unhealthy lifestyle habits can affect children's cardiometabolic health in a way that exceeds their separate effects.

23 Jul 2024

Proteins in blood may help to predict Parkinson’s disease up to seven years before the onset of motor symptoms

Researchers combined mass spectrometry-based proteomic phenotyping with machine learning to identify blood biomarkers in early Parkinson's disease.

20 Jun 2024

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024