MALDI TOF News and Research

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Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry is a soft ionization method used in the detection of various chemical compounds with a broad mass range. MALDI-TOF can be applied in biology to the study of nucleic acids and proteins.

Europe has a new mosquito problem, but it may not be the one you think

A scoping review of 91 studies, combined with a workshop involving 41 experts from six European countries, mapped the spread, biology, surveillance challenges, and potential disease relevance of the invasive mosquito Aedes koreicus. The researchers identified major gaps in species identification, vector competence, ecology, genetics, and long-term surveillance that must be addressed as the cold-tolerant mosquito expands across Europe.

2 Sep 2026

New non invasive way to diagnose childhood epilepsy through blood sugar patterns

A study published in Engineering has demonstrated that the N-glycome of serum-derived extracellular vesicles (EVs) can serve as a non-invasive biosignature for the diagnosis and classification of childhood epilepsy, offering a new tool for precision and longitudinal monitoring in clinical settings.

14 May 2026

New technique finds bacteria to increase the vitamin B2 content of soya drinks

Researchers at DTU have developed a new method that can reduce the time needed to find new bacteria for fermentation.

10 Apr 2026

Expert guidelines for fungal endophthalmitis in the Asia-Pacific region

Fungal eye infections affect millions globally, with an especially high incidence in South and Southeast Asia.

1 Dec 2025

Researchers map the complex sugar chains attached to rat serum proteins

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent variations with clear cell-type specificity.

24 Oct 2025

New strategies to tackle resistant foodborne pathogens

Innovative approaches in food and beverage analysis are transforming pathogen detection and control, emphasizing the role of natural compounds and sequencing.

19 Aug 2025

MALDI-TOF mass spectrometry proves effective for diagnosing onychomycosis in nail psoriasis

Nail psoriasis is common in patients with plaque psoriasis and is associated with morbidity, including onychomycosis, which can complicate psoriasis treatments and be difficult to differentiate.

26 Oct 2024

New breath-based test for lower respiratory tract infections shows 100% sensitivity in critical care settings

Researchers have developed a breath-based in vitro assay that accurately detects lower respiratory tract infections (LRTIs) by measuring neutrophil elastase activity. This non-invasive test offers high diagnostic sensitivity and could revolutionize LRTI detection.

29 Sep 2024

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Researchers discuss current evidence on Candida auris, an emerging multidrug-resistant yeast.

6 May 2024

Muscles in microgravity: Spaceflight duration impacts muscle protein stress markers

Study explores the differential effects of short and long-duration space missions on muscle protein nitrosylation in astronauts, indicating adaptations and potential impairments in muscle function due to microgravity, and highlights the role of inflight exercise in mitigating some negative effects on muscle health.

3 Apr 2024

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

Researchers developed the NOVA algorithm to systematically analyze bacterial isolates unidentified using traditional methods such as matrix-assisted laser desorption ionization-time of flight mass spectrometry and partial 16S rRNA gene sequencing using whole genome sequencing.

10 Jan 2024

First study to report isolation of M. saskatchewanense from medical devices

Researchers reported the first isolation of M. saskatchewanense from medical-grade equipment.

12 Dec 2023

Researchers develop new rapid and reliable method for SARS-CoV-2 detection

Commercially available mass spectrometers can reliably detect the SARS-CoV-2 coronavirus. In the journal "Clinical proteomics" researchers from the Martin Luther University Halle-Wittenberg (MLU) present a new method which employs equipment that is already being used in hospitals and laboratories to detect bacterial and fungal infections.

16 Aug 2023

Food preservative nisin: A gut game changer that safely alters microbiome composition

Nisin, a powerful bacteriocin, influences the gut microbiota and its functionality by modulating the abundance of specific bacterial groups and altering short-chain fatty acid synthesis.

18 May 2023

Study indicates that the planetary health diet increases probiotic-associated bacteria in the gut microbiome

Researchers analyzed whole-genome data from fecal samples of healthy volunteers following three diets

18 Apr 2023

A highly efficient platform for detection of SARS-CoV-2 variants

The recent outbreak of the coronavirus disease 2019 (COVID-19) pandemic and the continuous evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have highlighted the significance of new detection methods for global monitoring and prevention.

17 Apr 2023

Study details bacterial agents in 418 ticks extracted from humans in France

In a recent study published in the journal Emerging Infectious Diseases, researchers analyzed ticks that bit humans between January 2014 and March 2021 in France for the presence of bacterial pathogens.

27 Mar 2023

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

In a recent case report published in the U.S. Centers for Disease Control and Prevention’s (CDC) journal Emerging Infectious Diseases, researchers reported a case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Nocardia pseudobrasiliensis concomitant infection.

27 Mar 2023

Demographic, geographic, and temporal variables associated with C. auris cases in Italy

A recent study reported growing cases of Candida auris in North Italy.

27 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

MALDI TOF News and Research

Further Reading

Europe has a new mosquito problem, but it may not be the one you think

New non invasive way to diagnose childhood epilepsy through blood sugar patterns

New technique finds bacteria to increase the vitamin B2 content of soya drinks

Expert guidelines for fungal endophthalmitis in the Asia-Pacific region

Researchers map the complex sugar chains attached to rat serum proteins

New strategies to tackle resistant foodborne pathogens

MALDI-TOF mass spectrometry proves effective for diagnosing onychomycosis in nail psoriasis

New breath-based test for lower respiratory tract infections shows 100% sensitivity in critical care settings

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Muscles in microgravity: Spaceflight duration impacts muscle protein stress markers

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

First study to report isolation of M. saskatchewanense from medical devices

Researchers develop new rapid and reliable method for SARS-CoV-2 detection

Food preservative nisin: A gut game changer that safely alters microbiome composition

Study indicates that the planetary health diet increases probiotic-associated bacteria in the gut microbiome

A highly efficient platform for detection of SARS-CoV-2 variants

Study details bacterial agents in 418 ticks extracted from humans in France

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

Demographic, geographic, and temporal variables associated with C. auris cases in Italy

High-resolution mass spectrometric rapid identification of Candida auris

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