Mood Disorder News and Research

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Scientists map how chronic stress alters somatostatin levels in the brain

Consider the brake. Not the engine, which gets all the attention, but the brake, the quiet thing that decides how fast a system is allowed to go.

1 Jul 2026

Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care

A US electronic health record study found that adults with obesity who started semaglutide or tirzepatide had lower recorded hazards of anxiety and depression than matched patients using naltrexone-bupropion. However, among adults without type 2 diabetes, tirzepatide was linked to higher recorded hazards of anxiety and insomnia than semaglutide, underscoring the need for cautious monitoring.

1 Jul 2026

Cellular aging in immune cells signals early onset of cognitive depression

Blood tests measuring the aging of certain white blood cells can predict cognitive and mood-related symptoms of depression, rather than physical symptoms.

4 May 2026

Transcranial magnetic stimulation can be a cost-effective treatment option for depression

A major new study has found that transcranial magnetic stimulation (TMS), which applies magnetic energy to the brain, can be a cost-effective treatment option for the NHS in treating moderate and severe forms of depression that have not responded to other treatments.

27 Jan 2026

Short-term nitrous oxide treatment could benefit patients with major depressive disorder

Patients with major depressive disorder, including those who have not responded to first-line antidepressants, may benefit from short-term nitrous oxide treatment, a major meta-analysis led by the University of Birmingham has found.

1 Dec 2025

High-potassium diets show consistent mental health benefits

Higher intakes of certain dietary minerals are linked to lower depression risk, with potassium showing consistent benefits in both U.S. and Korean adults. Patterns differ by country, sex, and age, highlighting the role of cultural diets and nutrient bioavailability in mental health.

12 Aug 2025

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

Multiple chatbots simulate group therapy to help women manage premenstrual syndrome

A research team has designed and implemented a group motivational interviewing system using multiple chatbots to support premenstrual syndrome (PMS), a common disorder among women.

2 Jun 2025

Maternal medications linked to changes in protein and fat levels in human milk

The impact of maternal antidepressant and anti-inflammatory use on breast milk composition shows reduced protein and fat levels, affecting infant nutrition.

9 Jan 2025

Stimulant users are caught in fatal ‘fourth wave’ of opioid epidemic

In Pawtucket, Rhode Island, near a storefront advertising "free" cellphones, J.R. sat in an empty back stairwell and showed a reporter how he tries to avoid overdosing when he smokes crack cocaine.

3 Jan 2025

Predicting mood episodes with sleep data: A breakthrough for mental health care

Researchers developed a machine-learning model that uses only sleep-wake patterns to predict mood episodes in patients with mood disorders, achieving high accuracy. This approach simplifies real-world mental health monitoring using data from wearables or smartphones.

21 Nov 2024

Researchers uncover genetic link between bipolar disorder type I and epilepsy

A team of researchers from the Chinese Academy of Sciences has uncovered compelling evidence of a genetic link between bipolar disorder type I (BD-I) and epilepsy, potentially revolutionizing our understanding of these complex neuropsychiatric conditions.

30 Sep 2024

Type 1 diabetes in children linked to increased risk of mental health problems

Children diagnosed with type 1 diabetes are at significantly higher risk of a number of mental health issues, including mood and anxiety disorders, a study from a team in the UK and the Czech Republic has found.

18 Jul 2024

Innovative aiTBS therapy shortens treatment duration for bipolar disorder

A potential new treatment for bipolar disorder (BP) that significantly shortens treatment time has emerged, following a randomized clinical trial using accelerated intermittent theta burst stimulation (aiTBS).

11 Jul 2024

New study links COVID-19 to lasting neuropsychiatric issues, highlights vaccination benefits

COVID-19 survivors face significantly higher risks of developing neuropsychiatric conditions, but vaccination reduces these risks over time.

27 Jun 2024

CAMH research suggests potential targets for prevention and early identification of psychotic disorders

A new study by the Centre for Addiction and Mental Health (CAMH), entitled Mental Health Service Use Before First Diagnosis of a Psychotic Disorder and published in JAMA Psychiatry, found that nearly 75 per cent of young Ontarians with a psychotic disorder had at least one mental health service visit within the three years prior to their first diagnosis of the disorder.

21 Jun 2024

Emotional dysregulation identified as core symptom of ADHD

Cambridge scientists have shown that problems regulating emotions – which can manifest as depression, anxiety and explosive outbursts – may be a core symptom of attention deficit hyperactivity disorder (ADHD).

22 May 2024

Study: Omega-6 fatty acids could reduce the risk of bipolar disorder

Omega-6 fatty acids, commonly found in eggs, poultry, and seafood, could reduce the risk of bipolar disorder, according to a world-first study from the University of South Australia.

6 May 2024

Anger damages blood vessel function, raising heart disease risk

A recent study in the Journal of the American Heart Association reveals that provoked anger, but not sadness or anxiety, acutely impairs endothelial function, shedding light on the link between anger and cardiovascular events.

2 May 2024

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found to be linked with a lower risk for bipolar disorder, according to a new study in Biological Psychiatry, published by Elsevier.

30 Apr 2024