Multimorbidity News and Research

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Real-world data reveals higher reported GLP-1 side effects in female patients

The second of a Series of papers presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Obstetrics, Gynaecology & Women's Health discusses the wide-ranging issues relating to use of GLP-1 RA drug use in women.

1 Oct 2026

New study tracks rising heart and kidney risks in people with type 2 diabetes

The risk of developing chronic kidney disease (CKD) or heart failure (HF), or dying, following a type 2 diabetes (T2D) diagnosis increases substantially over time, according to new research being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

27 Sep 2026

Higher ultra-processed food intake linked to multiple health risks

A higher ultra processed food (UPF) intake is linked to a heightened risk of several major chronic health issues, such as digestive diseases, high blood pressure, and metabolic syndrome/diabetes, as well as death, finds a pooled data analysis of the available evidence, published in the open access journal Family Medicine and Community Health.

22 Sep 2026

Why frailty and heart health may be more closely connected than we thought

A narrative review proposes cardiovascular frailty as a distinct phenotype that brings together blood pressure regulation, vascular aging, oxi-inflammaging, and clinical frailty deficits. The authors argue that a validated cardiovascular frailty index could support earlier detection and personalized care, although longitudinal studies are needed before the concept can be used clinically.

15 Sep 2026

What your gut microbes may have to do with how your brain ages

This review examines how diet-driven changes in the gut microbiota and microbial metabolites may influence cognitive aging through immune, metabolic, neural, endocrine, and barrier-related pathways. It highlights SCFAs, tryptophan-derived metabolites, and bile acids as key signaling mediators while emphasizing that much of the mechanistic evidence remains preclinical and human evidence is largely associative.

3 Sep 2026

Study identifies three distinct BMI trajectories among people with type 2 diabetes

A recent study by the University of Eastern Finland identified three distinct body mass index (BMI) trajectories among people with type 2 diabetes.

1 Sep 2026

Multimorbidity linked to shorter lifespans in aging dogs

As dogs age, many develop more than one chronic health condition. New research from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) shows those conditions can dramatically shorten a dog's lifespan, highlighting the importance of managing multiple diseases together rather than individually.

31 Aug 2026

Diabetes study reveals differing health risks for men and women

In the years following type 2 diabetes diagnosis, women are more likely to develop mental health conditions, while men are more likely to develop cardiovascular and renal complications, according to a study published August 25th in the open access journal PLOS Medicine by Fabiola Eto from Queen Mary University of London, UK, and colleagues.

25 Aug 2026

These simple fitness tests revealed which older adults had the lowest death risk

Objective fitness tests in 13,423 Taiwanese adults aged 65 years or older linked better balance, agility, lower-body strength, and cardiorespiratory fitness with lower all-cause mortality over a median seven years. A multidomain fitness index showed the strongest association, suggesting that simple performance tests may add useful information to conventional geriatric risk assessment.

24 Aug 2026

Longer intervals between meals associated with faster accumulation of chronic diseases

Older adults who typically had longer intervals between meals accumulated chronic diseases more rapidly over time than those with shorter intervals, according to a study from Karolinska Institutet published in the Journal of Internal Medicine.

20 Aug 2026

The healthiest super-agers may have one thing in common: stable cognition

A 10-year study of 1,003 older adults linked cognitive super-aging to fewer emergency visits, unplanned hospital admissions, delirium episodes, dementia diagnoses, and residential aged care placements. Maintaining cognitive performance over time showed the strongest overall association with favorable health outcomes and was linked to a 46% lower mortality risk.

5 Aug 2026

Study links lower vitamin D to mood and cognitive health in adults over 85 with diabetes

Researchers studying 188 adults aged 85 years or older with type 2 diabetes found the lowest serum 25(OH)D concentrations among those with both depressive symptoms and mild cognitive impairment. Lower levels remained associated with having both conditions after adjustment for selected factors, but the cross-sectional study cannot establish causation or a benefit from supplementation.

3 Aug 2026

Two British birth cohorts find no added health burden from a coastal childhood

Researchers analyzing two British birth cohorts found no association between coastal residence in adolescence and midlife multimorbidity, while an unadjusted association in the 1958 cohort weakened after accounting for neighborhood deprivation.

3 Aug 2026

Coastal residents more likely to have worse midlife health

People who live by the coast in midlife are more likely to have worse health, finds a new study in England and Wales led by UCL researchers.

30 Jul 2026

Most hospital readmissions after heart failure are not heart-related

A study reveals that non-cardiovascular medications increase hospital readmission risks in heart failure patients, highlighting the need for better management.

8 Jul 2026

Scientists map blood chemistry links to hundreds of diseases

A UK Biobank study of nearly 390,000 people mapped 251 NMR-derived plasma metabolic traits against hundreds of health traits, prevalent diseases, and future disease outcomes. The atlas revealed tens of thousands of replicated associations, showed stronger prediction for selected short-term and cardiometabolic outcomes, and identified putative causal links that may guide future precision medicine research.

24 Jun 2026

England faces widening obesity inequalities across regions and communities

This study is the first to analyse obesity trends from 2019 to 2025, using NHS England electronic health records covering nearly 55 million adults.

24 Jun 2026

Frailty flags poorer blood pressure control in older women

In 1,038 older adults with hypertension attending outpatient clinics in Vietnam, frailty was more common in women than men, while overall rates of suboptimal blood pressure were similar by sex. Frailty was associated with about twice the odds of suboptimal blood pressure in women, but not in men, highlighting the need to study sex-specific and frailty-informed hypertension care.

8 Jun 2026

Scientists uncover shared gene signatures that reveal how mammals age

Researchers mapped more than 11,000 transcriptomes across mice, rats, macaques, and humans, revealing conserved molecular signatures of aging and mortality across tissues, species, and cell types. The study developed interpretable transcriptomic clocks that track age, mortality-related molecular change, chronic disease signals and responses to lifespan-altering interventions.

29 May 2026

Longevity science and public health must unite for aging populations

A new editorial was published in Volume 18 of Aging-US on May 18, 2026, titled "Public health in the age of longevity interventions: from prevention to system-wide resilience."

20 May 2026