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Scientists found a distinct gut microbiome pattern in people with symptomatic diverticular disease

A multicenter Japanese study found that symptomatic uncomplicated diverticular disease (SUDD) was associated with reduced gut microbial diversity, increased abundance of the Ruminococcus gnavus group, and depletion of Coprococcus and other butyrate-producing bacteria. Predictive microbiome analysis also identified enrichment of pathways linked to exopolysaccharide biosynthesis and the cell cycle, although the observational design means these associations cannot establish causality.

25 Aug 2026

Researchers map DNA's physical code using large-scale simulations

Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different genes. For regulatory proteins to reach these genes, DNA must be accessible.

20 Aug 2026

Pediatric rheumatic diseases have unique genetic architecture compared to adults

Researchers from Children's Hospital of Philadelphia (CHOP) have found that pediatric-onset rheumatic and inflammatory diseases have distinct genetic architecture compared with adults.

12 Aug 2026

Genetic study explains global spread of invasive longhorned ticks

The Asian longhorned tick, Haemaphysalis longicornis, spreads serious pathogens, including severe fever with thrombocytopenia syndrome (SFTS) virus, Rickettsia, and Theileria, and its bite can cause a meat allergy in humans.

4 Aug 2026

Genetic variants interact to increase early-onset atrial fibrillation risk

An estimated 10 million Americans have atrial fibrillation (AFib), according to the National Institutes of Health's National Heart, Lung, and Blood Institute.

31 Jul 2026

Scientists create programmable immune receptors for disease-resistant crops

Crop production faces threats from plant pathogens. Traditional disease-resistance breeding relies heavily on natural plant resistance genes that encode immune receptors adapted to particular pathogens.

23 Jul 2026

Higher neuroticism may curb strenuous exercise, genetic analysis suggests

Researchers used a UK survey and genetic data to examine whether higher neuroticism is associated with lower exercise engagement. Under the study’s Mendelian randomization assumptions, higher neuroticism was estimated to reduce participation in moderate and vigorous physical activity, while conscientiousness may lessen this effect.

23 Jul 2026

ddPCR and NGS for viral surveillance in antiviral drug development

hVIVO explains how ddPCR and NGS support viral surveillance in antiviral trials, from detection and quantification to resistance sequencing.

From hVIVO 20 Jul 2026

New approach enhances radiotherapy by disabling cancer's DNA repair machinery

Cancer treatments like radiation and chemotherapy work by doing one main thing: shredding the DNA of cancer cells so they can no longer multiply.

16 Jul 2026

Flavonoid-rich foods may blunt breast cancer risk tied to genetics

Higher flavodiet scores were associated with lower breast cancer risk among 93,271 UK Biobank females followed for a median of 11.8 years. The inverse association was particularly evident in women with high genetic risk, but the observational study cannot prove causation.

1 Jul 2026

Scientists discover 70 existing drugs that block deadly hantavirus infections

Researchers screened over 5,000 compounds and successfully pinpointed 70 existing drugs, including unexpected beta-lactam antibiotics, that effectively suppress Puumala orthohantavirus infection in human cells. This milestone drug-repurposing study provides an immediate, fast-tracked pipeline for developing the first approved treatments against life-threatening hantavirus diseases.

28 Jun 2026

Could your birth characteristics influence colorectal cancer risk?

A California study links birth and parental factors to early-onset colorectal cancer risk, highlighting male sex and Hispanic ethnicity as key contributors.

26 Jun 2026

Base editing technique reveals crucial gene for early human development

Research led by the University of Cambridge Loke Centre for Trophoblast Research has shown that a genome editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled detail.

25 Jun 2026

Statins may trigger muscle side effects by activating inflammatory danger signals

An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote low-level muscle myopathy by reducing isoprenoid-dependent protein prenylation rather than by cholesterol lowering. In primed muscle cells and mouse models, impaired YAP signaling, reduced glycolysis, NLRP3/caspase-1 activation, and nuclear FOXO accumulation increased atrogin-1, reduced protein synthesis, and weakened muscle function.

22 Jun 2026

Using the mathematics of quantum mechanics to improve neuroblastoma outcomes

For a child diagnosed with neuroblastoma-the most common infant cancer, occurring when early nerve cells grow out of control-the path to treatment isn't simple.

22 Jun 2026

Australia’s diphtheria outbreak shows why boosters, antibiotics, and better housing all matter

A 131-case diphtheria outbreak in Australia’s Northern Territory showed how toxigenic Corynebacterium diphtheriae can re-emerge even in highly vaccinated populations. Genomic and epidemiological evidence linked most cases to a dominant ST381 strain, with transmission shaped by overcrowding, poor skin health, and persistent health inequities.

15 Jun 2026