Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Space station study tests colorectal cancer tumor avatars in microgravity

Researchers from Wake Forest Institute for Regenerative Medicine (WFIRM) are studying how microgravity affects how models of colorectal cancer cells respond to chemotherapy aboard the International Space Station.

9 Nov 2026

Immune cell differences may explain sex-specific obesity responses

University of California, Riverside scientists have an explanation for why males and females respond differently to obesity.

6 Nov 2026

Review examines translational bottlenecks for plant-derived anti-inflammatory compounds

A review led by Professor Weidong Zhang at the School of Pharmacy, Naval Medical University, was published in Volume 2 of the journal Immunity & Inflammation on October 27, 2026. The article systematically examines the translational bottlenecks and potential solutions for plant-derived anti-inflammatory compounds.

5 Nov 2026

Organoid coculture platforms enhance preclinical prediction of drug efficacy

Three‐dimensional cancer organoids cultured in vitro closely recapitulate the phenotypic and genetic features of parental tumor tissues, making them powerful tools for cancer research, drug screening, and personalized medicine.

5 Nov 2026

Deep learning method maps spatial architecture of brain cancer cells

Glioblastoma is the deadliest and most common type of malignant brain tumour in adults. One of the reasons it's almost always incurable is that individual tumour cells are very different from one another and shift dynamically between various 'states'.

4 Nov 2026

Natural plant extract reduces cisplatin-induced kidney injury in mice

Acute kidney injury is common in hospitalized patients and rises sharply in intensive care, yet treatment options remain largely supportive.

3 Nov 2026

Spaceflight research opens new avenues for studying rare pediatric diseases

Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis rather than oxidative phosphorylation (OXPHOS), and incomplete tissue architecture.

3 Nov 2026

Skin organoids reveal how herpes simplex virus spreads between cells

Researchers at the Max Delbrück Center and University Medical Center Hamburg-Eppendorf have traced in skin organoids, how herpes simplex virus 1 infection progresses among neighboring skin cells, deepening our understanding.

30 Oct 2026

Space-grown organoids better replicate aggressive glioblastoma tumors

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and is one of the most aggressive and deadly forms of cancer.

30 Oct 2026

Atelerix and Frontier Space partner to enable biological sample preservation for space missions

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced a partnership with Frontier Space, a UK based space biotechnology company building platform technology for in-orbit R&D and biomanufacturing.

From Atelerix Ltd 28 Oct 2026

Ancient virus may help explain differences in human and chimpanzee brains

Pandemics can arise wherever animal or human populations are sufficiently large, and they are not confined to the modern age.

23 Oct 2026

Stem cell therapies may need new protein quality control standards

Current Good Manufacturing Practice (GMP) standards for cell therapies assess identity, viability, sterility, and genetic stability. For extracellular vesicle (EV) products, Minimal Information for Studies of Extracellular Vesicles (MISEV2023) guidance adds particle size, concentration, markers, morphology, contaminants, endotoxin, and assays.

22 Oct 2026

Maladaptive brain-state locking framework redefines chronic brain disorders

Neurodevelopmental, psychiatric, and neurodegenerative disorders are traditionally studied separately yet show overlapping disturbances in neural regulation and resilience.

21 Oct 2026

Cell Painting method reveals drug differences in 3D cancer cells

Researchers at Uppsala University have adapted Cell Painting, a widely used imaging method in drug discovery, to look at individual cells inside small 3D clusters of cancer cells.

21 Oct 2026

Bisphenol mixtures alter breast tissue development in lab-grown human models

Exposure to common chemicals may alter how normal human breast tissue develops, according to a new study from researchers at Tufts University School of Medicine and Boston University

15 Oct 2026

CSHL researchers find way to make immunotherapy effective against colorectal cancer

Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.

14 Oct 2026

Scientists identify the neuroblastoma cells that signal poor outcomes

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood.

10 Oct 2026

UCLA scientist develops new way to map cellular metabolism

Nutrition advice is everywhere. Eat more protein. Cut back on sugar. Get more fiber. But beneath all that advice is a surprisingly basic gap in our understanding: Scientists still have a limited view of what happens when specific nutrients reach individual cells inside the body.

6 Oct 2026

Cigarette smoke alters lung stem cells to drive specific cancers

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene alterations and ultimately helps determine the type of lung cancer that develops.

6 Oct 2026

Lab-grown human pituitary cells work and survive after transplantation into a primate

Researchers in Japan have transplanted pituitary tissue grown from human stem cells into a primate whose pituitary gland had been surgically removed, successfully restoring critical hormone signals.

1 Oct 2026